Termination and Pausing of RNA Polymerase II Downstream of Yeast Polyadenylation Sites

Methods in Yeast Genetics

1988 • 4,905 citations

Current protocols in molecular biology

1988 • 4,543 citations

Activators and targets

1990 • 582 citations

How the messenger got its tail: addition of poly(A) in the nucleus

1990 • 390 citations

A functional mRNA polyadenylation signal is required for transcription termination by RNA polymerase II.

1988 • 370 citations

Transcriptional interference and termination between duplicated α-globin gene constructs suggests a novel mechanism for gene regulation

1986 • 312 citations

Selective inhibition of activated but not basal transcription by the acidic activation domain of VP16: Evidence for transcriptional adaptors

1990 • 312 citations

How RNA polymerase II terminates transcription in higher eukaryotes

1989 • 301 citations

Definition of an efficient synthetic poly(A) site.

1989 • 285 citations

A poly(A) addition site and a downstream termination region are required for efficient cessation of transcription by RNA polymerase II in the mouse beta maj-globin gene.

1987 • 247 citations

Evidence for the biochemical role of an internal sequence in yeast nuclear mRNA introns: Implications for U1 RNA and metazoan mRNA splicing

1983 • 239 citations

Site-specific polyadenylation in a cell-free reaction

1984 • 223 citations

Nucleotide sequence of the yeast alcohol dehydrogenase II gene.

1983 • 208 citations

Expression of a beta-galactosidase gene containing the ribosomal protein 51 intron is sensitive to the rna2 mutation of yeast.

1983 • 180 citations

Accurate initiation at RNA polymerase II promoters in extracts from Saccharomyces cerevisiae.

1987 • 141 citations

RNA Processing Generates the Mature 3′ End of Yeast CYC1 Messenger RNA in Vitro

1988 • 129 citations

Distinct cis-acting signals enhance 3′ endpoint formation of CYC1 mRNA in the yeast Saccharomyces cerevisiae.

1991 • 128 citations

RNA polymerase: regulation of transcript elongation and termination

1991 • 127 citations

Analysis of the signals for transcription termination by purified RNA polymerase II

1990 • 113 citations

A pause site for RNA polymerase II is associated with termination of transcription.

1991 • 110 citations

Translational inactivation of ribosomal protein mRNAs during Xenopus oocyte maturation.

1988 • 106 citations

Transcription terminates near the poly(A) site in the CYC1 gene of the yeast Saccharomyces cerevisiae.

1989 • 82 citations

Transcription by RNA polymerase II induces changes of DNA topology in yeast.

1988 • 82 citations

Transcriptional termination between the closely linked human complement genes C2 and factor B: common termination factor for C2 and c-myc?

1991 • 77 citations

Signal sequence for generation of mRNA 3′ end in the Saccharomyces cerevisiae GAL7 gene.

1990 • 66 citations

Splice site selection dominates over poly(A) site choice in RNA production from complex adenovirus transcription units.

1988 • 64 citations

Conservation and evolution of transcriptional mechanisms in eukaryotes

1992 • 64 citations

The yeast actin intron contains a cryptic promoter that can be switched on by preventing transcriptional interference

1992 • 30 citations

Polymerase chain reaction mapping of yeastGAL7mRNA polyadenylation sites demonstrates that 3′ end processing invitrofaithfully reproduces the 3′ ends observedin vivo

1991 • 27 citations

Orientation-dependent function of a short CYC1 DNA fragment in directing mRNA 3' end formation in yeast.

1988 • 24 citations