Analysis in Cos-1 Cells of Processing and Polyadenylation Signals by Using Derivatives of the Herpes Simplex Virus Type 1 Thymidine Kinase Gene

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

1980 • 8,711 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

Construction and characterization of new cloning vehicle. II. A multipurpose cloning system

1977 • 3,829 citations

RNA molecular weight determinations by gel electrophoresis under denaturing conditions, a critical reexamination

1977 • 3,548 citations

Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.

1979 • 3,525 citations

Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids

1977 • 3,019 citations

3′ Non-coding region sequences in eukaryotic messenger RNA

1976 • 3,001 citations

Calcium-dependent bacteriophage DNA infection

1970 • 2,743 citations

SV40-transformed simian cells support the replication of early SV40 mutants

1981 • 2,564 citations

Why genes in pieces?

1978 • 2,256 citations

The isolation of structural genes from libraries of eucaryotic DNA

1978 • 1,877 citations

[68] Transcription maps of polyoma virus-specific RNA: Analysis by two-dimensional nuclease S1 gel mapping

1980 • 1,430 citations

Spliced segments at the 5′ terminus of adenovirus 2 late mRNA

1977 • 1,301 citations

Capping of eucaryotic mRNAs

1976 • 1,141 citations

Complete nucleotide sequence of SV40 DNA

1978 • 1,050 citations

The ovalbumin gene - sequence of putative control regions

1980 • 996 citations

The Genome of Simian Virus 40

1978 • 948 citations

Resolution of Multiple Ribonucleic Acid Species by Polyacrylamide Gel Electrophoresis^*

1967 • 866 citations

The sequence 5′-AAUAAA-3′ forms part of the recognition site for polyadenylation of late SV40 mRNAs

1981 • 819 citations

Nucleotide sequence of the ampicillin resistance gene of Escherichia coli plasmid pBR322.

1978 • 791 citations

Properties of a supercoiled deoxyribonucleic acid-protein relaxation complex and strand specificity of the relaxation event

1970 • 770 citations

Identification of DNA sequences required for transcription of the human α1-globin gene in a new SV40 host-vector system

1981 • 624 citations

Steps in the processing of Ad2 mRNA: Poly(A)+ Nuclear sequences are conserved and poly(A) addition precedes splicing

1978 • 478 citations

Efficient infection of monkey cells with DNA of simian virus 40.

1981 • 419 citations

Nucleotide sequence of the thymidine kinase gene of herpes simplex virus type 1.

1981 • 388 citations

Coding potential and regulatory signals of the polyoma virus genome

1980 • 369 citations

The primary transcription unit of the mouse β-Major globin gene

1981 • 358 citations

A Protein of Molecular Weight 78,000 Bound to the Polyadenylate Region of Eukaryotic Messenger RNAs

1973 • 347 citations

SV40 gene expression is modulated by the cooperative binding of T antigen to DNA

1981 • 300 citations

Exons encode functional and structural units of chicken lysozyme.

1980 • 273 citations

Tissue-specific expression of mouse α-amylase genes: Nucleotide sequence of isoenzyme mRNAs from pancreas and salivary gland

1980 • 259 citations

The Role of the Poly(A) Sequence in Mammalian Messenger RN

1981 • 254 citations

Transcripts from the Cellular Homologs of Retroviral Oncogenes: Distribution Among Chicken Tissues

1982 • 241 citations

Transcripts from the adenovirus-2 major late promoter yield a single early family of 3′ coterminal mRNAs and five late families

1980 • 235 citations

Structure and genomic organization of the mouse dihydrofolate reductase gene

1980 • 218 citations

Recent developments in the molecular genetics of human hemoglobin

1979 • 199 citations

Mapping the spliced and unspliced late lytic SV40 RNAs

1978 • 193 citations

Construction and characterization of a recombinant plasmid encoding the gene for the thymidine kinase of herpes simplex type 1 virus

1979 • 189 citations

Globin mRNA Species Containing Poly(A) Segments of Different Lengths

1976 • 183 citations

Controls of RNA splicing and termination in the major late adenovirus transcription unit

1981 • 169 citations

The major late adenovirus type-2 transcription unit: Termination is downstream from the last poly(A) site

1979 • 141 citations

Transcription pattern of in vivo-labeled late simian virus 40 RNA: equimolar transcription beyond the mRNA 3' terminus

1978 • 140 citations

The association of protein with the polyadenylic acid of HeLa cell messenger RNA: Evidence for a “Transport” role of a 75,000 molecular weight polypeptide

1976 • 118 citations

Isolation and Characterization of Simian Virus 40 Ribonucleic Acid

1972 • 118 citations

Posttranscriptional Selection of Simian Virus 40-Specific RNA

1975 • 112 citations

Structure of two adenovirus type 12 transforming polypeptides and their evolutionary implications

1980 • 97 citations

Transcription units of adenovirus type 2

1980 • 96 citations

Expression of simian virus 40-rat preproinsulin recombinants in monkey kidney cells: use of preproinsulin RNA processing signals.

1981 • 94 citations

Biochemical procedure for production of small deletions in simian virus 40 DNA.

1975 • 93 citations

Nuclear RNA is spliced in the absence of poly(A) addition

1981 • 84 citations

The Regulatory Function of Poly(A) and Adjacent 3' Sequences in Translated RNA

1982 • 80 citations

Amplification in the leader sequence of late polyoma virus mRNAs

1979 • 78 citations

Polyoma virus giant RNAs contain tandem repeats of the nucleotide sequence of the entire viral genome.

1978 • 73 citations

Adenovirus type 2 late mRNA's: structural evidence for 3'-coterminal species

1978 • 72 citations

Translational stability of native and deadenylylated rabbit globin mRNA injected into HeLa cells.

1981 • 70 citations

Control of breakdown of the polyadenylate sequence in mammalian polyribosomes: role of poly(adenylic acid)-protein interactions

1977 • 68 citations

Two regions of the adenovirus 2 genome specify families of late polysomal RNAs containing common sequences.

1978 • 60 citations

Strand-Specific Transcription of Polyoma Virus DNA Early in Productive Infection and in Transformed Cells

1976 • 51 citations

Addition of poly(A) to nuclear RNA occurs soon after RNA synthesis.

1980 • 46 citations

Poly(A) sites of adenovirus serotype 2 transcription units

1982 • 36 citations

Construction and Characterization of Viable Deletion Mutants of Simian Virus 40 Lacking Sequences near the 3′ End of the Early Region

1982 • 36 citations

Loss of the polyadenylate segment from mammalian messenger RNA

1980 • 35 citations

Nucleotide Sequence about the 3' Terminus of SV40 DNA Transcripts and the Region Where DNA Synthesis Is Initiated

1974 • 35 citations

Simian virus 40-rabbit beta-globin recombinants lacking late mRNA splice sites express cytoplasmic RNAs with altered structures

1982 • 29 citations

Viral gene expression in polyoma virus-transformed rat cells and their cured revertants

1981 • 24 citations

Extent of Transcription of the E Strand of Polyoma Virus DNA During the Early Phase of Productive Infection

1978 • 22 citations