Antibodies Specific for the Human Retinoblastoma Protein Identify a Family of Related Polypeptides

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Film Detection Method for Tritium‐Labelled Proteins and Nucleic Acids in Polyacrylamide Gels

1974 • 8,693 citations

Antibodies: A laboratory manual

1989 • 4,532 citations

The Human Papilloma Virus-16 E7 Oncoprotein Is Able to Bind to the Retinoblastoma Gene Product

1989 • 3,036 citations

Expression of recessive alleles by chromosomal mechanisms in retinoblastoma

1983 • 1,952 citations

Molecular themes in oncogenesis

1991 • 1,663 citations

SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene

1988 • 1,490 citations

Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

1988 • 1,440 citations

Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product.

1989 • 1,186 citations

Monoclonal antibodies specific for simian virus 40 tumor antigens

1981 • 1,110 citations

Abnormalities in Structure and Expression of the Human Retinoblastoma Gene in SCLC

1988 • 905 citations

Suppression of the Neoplastic Phenotype by Replacement of the RB Gene in Human Cancer Cells

1988 • 832 citations

Tumor suppressor genes

1991 • 775 citations

Cellular targets for transformation by the adenovirus E1A proteins

1989 • 747 citations

Inactivation of the Retinoblastoma Susceptibility Gene in Human Breast Cancers

1988 • 608 citations

Suppression of Tumorigenicity of Human Prostate Carcinoma Cells by Replacing a Mutated RB Gene

1990 • 606 citations

Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells.

1990 • 543 citations

Retinoblastoma: Clues to Human Oncogenesis

1984 • 495 citations

Deletions of a DNA sequence in retinoblastomas and mesenchymal tumors: organization of the sequence and its encoded protein.

1987 • 432 citations

Point Mutational Inactivation of the Retinoblastoma Antioncogene

1989 • 427 citations

Structural Rearrangement of the Retinoblastoma Gene in Human Breast Carcinoma

1988 • 423 citations

Monoclonal antibodies specific for adenovirus early region 1A proteins: extensive heterogeneity in early region 1A products

1985 • 417 citations

Promoter deletion and loss of retinoblastoma gene expression in human prostate carcinoma.

1990 • 342 citations

The regions of the retinoblastoma protein needed for binding to adenovirus E1A or SV40 large T antigen are common sites for mutations.

1990 • 327 citations

The cellular 107K protein that binds to adenovirus E1A also associates with the large T antigens of SV40 and JC virus

1989 • 307 citations

Oncogenic Point Mutations in the Human Retinoblastoma Gene: Their Application to Genetic Counseling

1989 • 288 citations

An N-Terminal transformation-governing sequence of SV40 large T antigen contributes to the binding of both p110 and a second cellular protein, p120

1989 • 235 citations

Two regions of the adenovirus early region 1A proteins are required for transformation

1988 • 232 citations

Detection of cellular proteins associated with human adenovirus type 5 early region 1A polypeptides

1985 • 227 citations

Preferential mutation of paternally derived RB gene as the initial event in sporadic osteosarcoma

1989 • 221 citations

Two distinct and frequently mutated regions of retinoblastoma protein are required for binding to SV40 T antigen.

1990 • 204 citations

A region of SV40 large T antigen can substitute for a transforming domain of the adenovirus E1A products

1988 • 167 citations

Some retinoblastomas, osteosarcomas, and soft tissue sarcomas may share a common etiology.

1988 • 137 citations

The retinoblastoma gene and cell growth control

1990 • 91 citations