Human Thymidine Kinase Gene: Molecular Cloning and Nucleotide Sequence of a cDNA Expressible in Mammalian Cells

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

The pUC plasmids, an M13mp7-derived system for insertion mutagenesis and sequencing with synthetic universal primers

1982 • 6,153 citations

A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments

1982 • 3,041 citations

Nonchromosomal Antibiotic Resistance in Bacteria: Genetic Transformation of Escherichia coli by R-Factor DNA

1972 • 2,842 citations

Plasmid screening at high colony density

1980 • 1,100 citations

Random subcloning of sonicated DNA: Application to shotgun DNA sequence analysis

1983 • 605 citations

A simple method to recover intact high molecular weight RNA and DNA after electrophoretic separation in low gelling temperature agarose gels

1979 • 460 citations

Nucleotide sequence of the thymidine kinase gene of herpes simplex virus type 1.

1981 • 388 citations

Isolation and characterization of a full-length expressible cDNA for human hypoxanthine phosphoribosyl transferase.

1983 • 299 citations

Functional relationships between transcriptional control signals of the thymidine kinase gene of herpes simplex virus

1982 • 253 citations

Regulation of thymidine kinase synthesis in human cells*1

1974 • 215 citations

Isolation of the chicken thymidine kinase gene by plasmid rescue

1980 • 208 citations

Construction and characterization of a recombinant plasmid encoding the gene for the thymidine kinase of herpes simplex type 1 virus

1979 • 189 citations

A rapid and efficient procedure for the purification of DNA from agarose gels

1980 • 174 citations

Molecular cloning and cell cycle-specific regulation of a functional human thymidine kinase gene.

1983 • 84 citations

The nucleotide sequence of the chicken thymidine kinase gene and the relationship of its predicted polypeptide to that of the vaccinia virus thymidine kinase

1984 • 76 citations

Direct isolation of the functional human thymidine kinase gene with a cosmid shuttle vector.

1984 • 68 citations

Approaches to rapid DNA sequence analysis

1983 • 66 citations

A cDNA Cloning Vector That Permits Expression of cDNA Inserts in Mammalian Cells

1983 • 55 citations

Genomic cloning and preliminary characterization of the human thymidine kinase gene.

1983 • 50 citations

DNA synthesis and DNA enzymes in terminally differentiating cardiac muscle cells

1979 • 44 citations

Isolation and Preliminary Characterization of the Chinese Hamster Thymidine Kinase Gene

1983 • 40 citations

tk Enzyme Expression in Differentiating Muscle Cells Is Regulated Through an Internal Segment of the Cellular tk Gene

1984 • 38 citations

Human thymidine kinase. Purification and properties of the cytosolic enzyme of placenta.

1983 • 32 citations

Partial purification and characterization of the mRNA for human thymidine kinase and hypoxanthine/guanine phosphoribosyltransferase.

1982 • 20 citations

Biochemical and immunological characterization of deoxythymidine kinase of thymidine kinaseless HeLa cells biochemically transformed by herpes simplex virus type

1977 • 17 citations

Genetic and Physical Analysis of the Chicken tk Gene

1984 • 16 citations