Transfection of the EJ rasHa gene into keratinocytes derived from carcinogen-induced mouse papillomas causes malignant progression.

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

1983 • 2,871 citations

Calcium regulation of growth and differentiation of mouse epidermal cells in culture

1980 • 1,810 citations

Cancer Epidemiology and Prevention

1997 • 1,433 citations

Mechanism of activation of a human oncogene

1982 • 1,417 citations

Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture

1983 • 1,358 citations

Transforming genes of human bladder and lung carcinoma cell lines are homologous to the ras genes of Harvey and Kirsten sarcoma viruses.

1982 • 775 citations

Activation of the mouse cellular Harvey-ras gene in chemically induced benign skin papillomas

1984 • 550 citations

Fibroblast immortality is a prerequisite for transformation by EJ c-Ha-ras oncogene

1983 • 446 citations

Malignant conversion of mouse skin tumours is increased by tumour initiators and unaffected by tumour promoters

1983 • 325 citations

A survey of transformation markers in differentiating epidermal cell lines in culture.

1980 • 320 citations

Mouse skin cells resistant to terminal differentiation associated with initiation of carcinogenesis

1981 • 228 citations

Neoplastic Transformation of Human Epidermal Keratinocytes by AD12-SV40 and Kirsten Sarcoma Viruses

1985 • 223 citations

Enhancing the efficiency of DNA-mediated gene transfer in mammalian cells

1981 • 208 citations

Induction of papillomas with a high probability of conversion to malignancy

1985 • 132 citations

Keratinocytes blocked in phorbol ester-responsive early stage of terminal differentiation by sarcoma viruses

1985 • 112 citations

Papillomas induced by initiation–promotion differ from those induced by carcinogen alone

1983 • 90 citations

Quantitative assay for carcinogen altered differentiation in mouse epidermal cells

1980 • 88 citations

Regression kinetics of mouse skin papillomas.

1976 • 77 citations

Two-stage tumor promotion in mouse skin: An alternative interpretation

1985 • 75 citations

Members of the src and ras oncogene families supplant the epidermal growth factor requirement of BALB/MK-2 keratinocytes and induce distinct alterations in their terminal differentiation program.

1985 • 74 citations

Definition of the 5′ and 3′ ends of transcripts of the ovalbumin gene

1980 • 62 citations

Evidence for multiple steps in neoplastic transformation of normal and preneoplastic Syrian hamster embryo cells following transfection with Harvey murine sarcoma virus oncogene (v-Ha-ras).

1985 • 60 citations

Association of resistance to terminal differentiation with initiation of carcinogenesis in adult mouse epidermal cells.

1985 • 58 citations

Evidence for a new model of tumor progression from carcinogenesis and tumor promotion studies with 7-bromomethylbenz[a]anthracene.

1983 • 37 citations

Proto-oncogene expression during two-stage carcinogenesis in mouse skin

1985 • 35 citations

Correlation of initiating potency of skin carcinogens with potency to induce resistance to terminal differentiation in cultured mouse keratinocytes.

1985 • 30 citations

Cellular and molecular changes during chemical carcinogenesis in mouse skin cells.

1985 • 16 citations