PERITRANSPLANT TOLERANCE INDUCTION WITH ANTI-CD3-IMMUNOTOXIN

The Dendritic Cell System and its Role in Immunogenicity

1991 • 4,733 citations

Function and Activation of NF-kappaB in the Immune System

1994 • 4,698 citations

Nuclear Factor-κB — A Pivotal Transcription Factor in Chronic Inflammatory Diseases

1997 • 4,661 citations

Interleukin-12: A Proinflammatory Cytokine with Immunoregulatory Functions that Bridge Innate Resistance and Antigen-Specific Adaptive Immunity

1995 • 2,437 citations

Immunosuppression by Glucocorticoids: Inhibition of NF-κB Activity Through Induction of IκB Synthesis

1995 • 2,386 citations

Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways

1996 • 1,457 citations

Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells

1997 • 1,143 citations

Regulation of the Interleukin (IL)-12R β2 Subunit Expression in Developing T Helper 1 (Th1) and Th2 Cells

1997 • 1,022 citations

Selective Expression of an Interleukin-12 Receptor Component by Human T Helper 1 Cells

1997 • 783 citations

Neonatal Tolerance Revisited: Turning on Newborn T Cells with Dendritic Cells

1996 • 770 citations

Developmental regulation of MHC class II transport in mouse dendritic cells

1997 • 754 citations

Inhibition of Angiogenesis In Vivo by Interleukin 12

1995 • 734 citations

Mixed Allogeneic Chimerism And Renal Allograft Tolerance In Cynomolgus Monkeys

1995 • 552 citations

Developmental commitment to the Th2 lineage by extinction of IL-12 signaling

1995 • 429 citations

Administration of recombinant IL-12 to normal mice enhances cytolytic lymphocyte activity and induces production of IFN-γ in vivo

1994 • 373 citations

Induction of high levels of allogeneic hematopoietic reconstitution and donor-specific tolerance without myelosuppressive conditioning

1997 • 317 citations

The Th1/Th2 paradigm and the allograft response

1996 • 262 citations

FN18-CRM9 IMMUNOTOXIN PROMOTES TOLERANCE IN PRIMATE RENAL ALLOGRAFTS1

1997 • 212 citations

Mechanisms of Peripheral Tolerance and Suppression Induced by Monoclonal Antibodies to CD4 and CD8

1996 • 195 citations

MODIFICATIONS OF THE CONDITIONING REGIMEN FOR ACHIEVING MIXED CHIMERISM AND DONOR-SPECIFIC TOLERANCE IN CYNOMOLGUS MONKEYS1

1997 • 187 citations

Mixed allogeneic chimerism as an approach to transplantation tolerance

1988 • 173 citations

ARE Th2 HELPER T LYMPHOCYTES BENEFICIAL, DELETERIOUS, OR IRRELEVANT IN PROMOTING ALLOGRAFT SURVIVAL?1

1997 • 170 citations

KIDNEY ALLOGRAFT TOLERANCE IN PRIMATES WITHOUT CHRONIC IMMUNOSUPPRESSION-THE ROLE OF VETO CELLS

1991 • 140 citations

FURTHER STUDIES OF VETO ACTIVITY IN RHESUS MONKEY BONE MARROW IN RELATION TO ALLOGRAFT TOLERANCE AND CHIMERISM

1994 • 130 citations

PRECLINICAL STUDIES OF ALLOGRAFT TOLERANCE IN RHESUS MONKEYS

1997 • 129 citations

ACUTE REJECTION OF VASCULARIZED HEART ALLOGRAFTS IN THE ABSENCE OF IFN??1,2

1996 • 112 citations

PROMOTION OF INCOMPATIBLE ALLOGRAFT ACCEPTANCE IN RHESUS MONKEYS GIVEN POSTTRANSPLANT ANTITHYMOCYTE GLOBULIN AND DONOR BONE MARROW

1987 • 101 citations

MANIPULATION OF CYTOKINE NETWORKS IN TRANSPLANTATION

1997 • 99 citations

Evolutionary stability of transspecies major histocompatibility complex class II DRB lineages in humans and rhesus monkeys

1992 • 88 citations

A New Reagent for the Induction of T-Cell Depletion, Anti-CD3-CRM9

1996 • 84 citations

Chimerism and central tolerance

1996 • 82 citations

Heart transplants in interferon-gamma, interleukin 4, and interleukin 10 knockout mice. Recipient environment alters graft rejection.

1997 • 66 citations

Induction of tolerance by intrathymic inoculation of alloantigen

1996 • 64 citations

In vivo T-cell ablation by a holo-immunotoxin directed at human CD3.

1992 • 59 citations

Prevention of immunotoxin-mediated vascular leak syndrome in rats with retention of antitumor activity.

1994 • 58 citations

Elucidating the Mechanism of Action of the Immunosuppressant 15-Deoxyspergualin

1995 • 48 citations

The Facilitating Effect Of One-Dr Antigen Sharing In Renal Allograft Tolerance Induced By Donor Bone Marrow In Rhesus Monkeys

1995 • 48 citations

THE DEVELOPMENT OF A POSTTRANSPLANT TLI TREATMENT STRATEGY THAT PROMOTES ORGAN ALLOGRAFT ACCEPTANCE WITHOUT CHRONIC IMMUNOSUPPRESSION>

1992 • 44 citations

SURVIVAL OF PRIMATES FOLLOWING ORTHOTOPIC CARDIAC TRANSPLANTATION TREATED WITH TOTAL LYMPHOID IRRADIATION AND CHEMICAL IMMUNE SUPPRESSION

1981 • 44 citations

CARDIAC ALLOGRAFT SURVIVAL IN RHESUS PRIMATES TREATED WITH COMBINED TOTAL LYMPHOID IRRADIATION AND RABBIT ANTITHYMOCYTE GLOBULIN

1979 • 43 citations

PROMOTION OF INCOMPATIBLE ALLOGRAFT ACCEPTANCE IN RHESUS MONKEYS GIVEN POSTTRANSPLANT ANTITHYMOCYTE GLOBULIN AND DONOR BONE MARROW

1989 • 41 citations

Regulation of Interleukin-12 Signalling During T Helper Phenotype Development

1996 • 33 citations

TRANSPLANTATION TOLERANCE IN PRIMATES FOLLOWING TOTAL LYMPHOID IRRADIATION AND ALLOGENEIC BONE MARROW INJECTION II. RENAL ALLOGRAFTS

1980 • 30 citations

COMPLETE WITHDRAWAL OF IMMUNOSUPPRESSION IN ALLOGRAFT RECIPIENTS

1996 • 21 citations

Role of the type I interferons in allograft rejection

1996 • 19 citations

Anti-T cell immunotoxins: a look at post-endocytotic receptor-mediated routing

1993 • 12 citations

CARDIAC ALLOGRAFT SURVIVAL ACROSS MAJOR HISTOCOMPATIBILITY COMPLEX BARRIERS IN THE RHESUS AUTOLOGOUS MARROW TRANSPLANTATION MONKEY FOLLOWING T LYMPHOCYTE-DEPLETED

1989 • 11 citations