Truncated Protein Phosphatase GLC7 Restores Translational Activation of GCN4 Expression in Yeast Mutants Defective for the eIF-2α Kinase GCN2

Molecular cloning: A laboratory manual

1990 • 85,659 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains

1988 • 5,115 citations

Methods in Yeast Genetics

1988 • 4,905 citations

THE STRUCTURE AND REGULATION OF PROTEIN PHOSPHATASES

1989 • 2,518 citations

A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformaion of Escherichia coli

1987 • 2,493 citations

A positive selection for mutants lacking orotidine-5′-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance

1984 • 2,401 citations

PROTEIN SERINE/THREONINE KINASES

1987 • 1,457 citations

In yeast, RAS proteins are controlling elements of adenylate cyclase

1985 • 1,142 citations

TRANSLATIONAL CONTROL IN MAMMALIAN CELLS

1991 • 1,041 citations

Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

1990 • 1,003 citations

Sterile host yeasts (SHY): A eukaryotic system of biological containment for recombinant DNA experiments

1979 • 967 citations

Phosphorylation of initiation factor 2α by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast

1992 • 768 citations

Multiple upstream AUG codons mediate translational control of GCN4

1986 • 654 citations

The fission yeast dis2+ gene required for chromosome disjoining encodes one of two putative type 1 protein phosphatases

1989 • 486 citations

The Protein Phosphatases Involved in Cellular Regulation. 1. Classification and Substrate Specificities

1983 • 471 citations

Mechanisms of gene regulation in the general control of amino acid biosynthesis in Saccharomyces cerevisiae

1988 • 449 citations

The structure of transposable yeast mating type loci

1980 • 439 citations

The role of protein phosphorylation in the hormonal control of enzyme activity

1985 • 377 citations

Distinct, essential roles of type 1 and 2A protein phosphatases in the control of the fission yeast cell division cycle

1990 • 339 citations

Autophosphorylation of the protein kinase dependent on double-stranded RNA.

1987 • 301 citations

Positive regulation in the general amino acid control of Saccharomyces cerevisiae.

1983 • 279 citations

Juxtaposition of domains homologous to protein kinases and histidyl-tRNA synthetases in GCN2 protein suggests a mechanism for coupling GCN4 expression to amino acid availability.

1989 • 278 citations

Vector systems for the expression, analysis and cloning of DNA sequence in S. cerevisiae

1985 • 265 citations

Translational Regulation of Gene Expression 2

1993 • 202 citations

Yeast translation initiation suppressor sui2 encodes the alpha subunit of eukaryotic initiation factor 2 and shares sequence identity with the human alpha subunit.

1989 • 201 citations

Cloning of the cDNA of the heme-regulated eukaryotic initiation factor 2 alpha (eIF-2 alpha) kinase of rabbit reticulocytes: homology to yeast GCN2 protein kinase and human double-stranded-RNA-dependent eIF-2 alpha kinase.

1991 • 200 citations

The ras oncogene--an important regulatory element in lower eucaryotic organisms

1989 • 189 citations

RAS2 of Saccharomyces cerevisiae is required for gluconeogenic growth and proper response to nutrient limitation.

1985 • 168 citations

GAC1 may encode a regulatory subunit for protein phosphatase type 1 in Saccharomyces cerevisiae.

1992 • 158 citations

Two glycogen synthase isoforms in Saccharomyces cerevisiae are coded by distinct genes that are differentially controlled

1991 • 154 citations

The yeast GLC7 gene required for glycogen accumulation encodes a type 1 protein phosphatase.

1991 • 153 citations

Isolation and sequence analysis of a cDNA clone encoding a type‐1 protein phosphatase catalytic subunit: Homology with protein phosphatase 2A

1987 • 128 citations

A Tn 10-lacZ-kanR-URA3 Gene Fusion Transposon for Insertion Mutagenesis and Fusion Analysis of Yeast and Bacterial Genes

1987 • 100 citations

The translational activator GCN3 functions downstream from GCN1 and GCN2 in the regulatory pathway that couples GCN4 expression to amino acid availability in Saccharomyces cerevisiae.

1990 • 99 citations

SUPPRESSORS OF THE ras2 MUTATION OF SACCHAROMYCES CEREVISIAE

1986 • 98 citations

Heritable Glycogen-storage Deficiency in Yeast and its Induction by Ultra-violet Light

1968 • 93 citations

Activity of protein phosphatases against initiation factor-2 and elongation factor-2

1990 • 80 citations

Purification and characterization of glycogen synthase from a glycogen-deficient strain of Saccharomyces cerevisiae.

1990 • 62 citations

Role of Transfer Ribonucleic Acids in the Regulation of Several Biosyntheses in Saccharomyces cerevisiae

1976 • 54 citations

A type 1 phosphoprotein phosphatase active with phosphorylated Mr = 68,000 initiation factor 2 kinase

1989 • 47 citations

Separation and identification of type 1 and type 2 protein phosphatases from rabbit reticulocyte lysates.

1983 • 45 citations

The gene DIS2S1 is essential in Saccharomyces cerevisiae and is involved in glycogen phosphorylase activation

1991 • 43 citations

Effects of skeletal muscle protein phosphatase inhibitor-2 on protein synthesis and protein phosphorylation in rabbit reticulocyte lysates

1982 • 38 citations

The histidine tRNA genes of yeast.

1983 • 21 citations