Low level expression of glycine receptor beta subunit transgene is sufficient for phenotype correction in spastic mice.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family

1985 • 2,145 citations

Widespread expression of glycine receptor subunit mRNAs in the adult and developing rat brain.

1991 • 548 citations

Mutations in the α1 subunit of the inhibitory glycine receptor cause the dominant neurologic disorder, hyperekplexia

1993 • 540 citations

Expression and regulation of Escherichia coli lacZ gene fusions in mammalian cells.

1983 • 471 citations

Identification of a gephyrin binding motif on the glycine receptor β subunit

1995 • 410 citations

Conserved quaternary structure of ligand-gated ion channels: the postsynaptic glycine receptor is a pentamer.

1988 • 388 citations

Glycine receptor heterogeneity in rat spinal cord during postnatal development.

1988 • 383 citations

Purification by affinity chromatography of the glycine receptor of rat spinal cord.

1982 • 370 citations

Transgenic mice expressing β-galactosidase in mature neurons under neuron-specific enolase promoter control

1990 • 360 citations

Monoclonal antibodies and peptide mapping reveal structural similarities between the subunits of the glycine receptor of rat spinal cord.

1984 • 335 citations

Glycine immunoreactivity localized in the cochlear nucleus and superior olivary complex

1987 • 310 citations

Alpha subunit variants of the human glycine receptor: primary structures, functional expression and chromosomal localization of the corresponding genes.

1990 • 272 citations

Residues within transmembrane segment M2 determine chloride conductance of glycine receptor homo- and hetero-oligomers.

1993 • 239 citations

Cloning and expression of the 58 kd β subunit of the inhibitory glycine receptor

1990 • 237 citations

Glycine receptor β–subunit gene mutation in spastic mouse associated with LINE–1 element insertion

1994 • 208 citations

The inhibitory glycine receptor: architecture, synaptic localization and molecular pathology of a postsynaptic ion-channel complex

1995 • 205 citations

Functional expression in Xenopus oocytes of the strychnine binding 48 kd subunit of the glycine receptor.

1989 • 192 citations

A missense mutation in the gene encoding the α1 subunit of the inhibitory glycine receptor in the spasmodic mouse

1994 • 191 citations

The spastic mouse: Aberrant splicing of glycine receptor β subunit mRNA caused by intronic insertion of Ll element

1994 • 185 citations

Assembly of the inhibitory glycine receptor: Identification of amino acid sequence motifs governing subunit stoichiometry

1993 • 183 citations

Decreased agonist affinity and chloride conductance of mutant glycine receptors associated with human hereditary hyperekplexia.

1994 • 168 citations

Functional chloride channels by mammalian cell expression of rat glycine receptor subunit

1989 • 159 citations

Neuroanatomical distribution of receptors for three potential inhibitory neurotransmitters in the brainstem auditory nuclei of the cat

1988 • 158 citations

Expression of interstitial collagenase during skeletal development of the mouse is restricted to osteoblast-like cells and hypertrophic chondrocytes.

1995 • 150 citations

Evidence for recessive as well as dominant forms of startle disease (hyperekplexia) caused by mutations in the α₁ subunit of the inhibitory glycine receptor

1994 • 141 citations

Structural analysis of mouse glycine receptor alpha subunit genes. Identification and chromosomal localization of a novel variant.

1994 • 136 citations

Targeting of Glycine Receptor Subunits to Gephyrin-Rich Domains in Transfected Human Embryonic Kidney Cells

1995 • 132 citations

Isoform-selective deficit of glycine receptors in the mouse mutant spastic

1992 • 125 citations

The glycine receptor deficiency of the mutant mouse spastic: evidence for normal glycine receptor structure and localization

1986 • 125 citations

Startle disease mutations reduce the agonist sensitivity of the human inhibitory glycine receptor.

1994 • 120 citations

Glycine receptor alteration in the mutant mouse spastic

1982 • 117 citations

A frameshift mutation in the mouse α₁ glycine receptor gene (Gira1) results in progressive neurological symptoms and juvenile death

1994 • 117 citations

Point mutation of glycine receptor α1 subunit in the spasmodic mouse affects agonist responses

1994 • 98 citations

Regional distribution of the cells expressing glycine receptor β subunit mRNA in the rat brain

1991 • 74 citations

Deficit of Spinal Cord Glycine/Strychnine Receptors in Inherited Myoclonus of Poll Hereford Calves

1988 • 63 citations

Deficit of inhibitory glycine receptors in spinal cord from Peruvian Pasos: evidence for an equine form of inherited myoclonus

1993 • 33 citations

Influence of Aminooxyacetic Acid, a -Aminobutyrate Transaminase Inhibitor, on Hereditary Spastic Defect in the Mouse.

1962 • 31 citations

An additional family with Startle disease and a G1192A mutation at the α1 subunit of the inhibitory glycine receptor gene

1994 • 23 citations

Behavior, genetics and biochemistry of an allele of the mutant mouse spastic, sp^alb

1987 • 5 citations

Behavior, genetics and biochemistry of an allele of the mutant mouse spastic,spa^Alb

1987 • 1 citations