Decreased agonist affinity and chloride conductance of mutant glycine receptors associated with human hereditary hyperekplexia.

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

The Time Course of Glutamate in the Synaptic Cleft

1992 • 1,071 citations

Widespread expression of glycine receptor subunit mRNAs in the adult and developing rat brain.

1991 • 548 citations

Mutations in the α1 subunit of the inhibitory glycine receptor cause the dominant neurologic disorder, hyperekplexia

1993 • 540 citations

Interaction at end-plate receptors between different choline derivatives

1957 • 477 citations

GABAA receptor needs two homologous domains of the & beta;-subunit for activation by GABA but not by pentobarbital

1993 • 417 citations

Strychnine Binding Associated with Glycine Receptors of the Central Nervous System

1973 • 388 citations

Conserved quaternary structure of ligand-gated ion channels: the postsynaptic glycine receptor is a pentamer.

1988 • 388 citations

Alpha subunit variants of the human glycine receptor: primary structures, functional expression and chromosomal localization of the corresponding genes.

1990 • 272 citations

Functional expression in Xenopus oocytes of the strychnine binding 48 kd subunit of the glycine receptor.

1989 • 192 citations

Assembly of the inhibitory glycine receptor: Identification of amino acid sequence motifs governing subunit stoichiometry

1993 • 183 citations

A single amino acid exchange alters the pharmacology of neonatal rat glycine receptor subunit

1990 • 183 citations

Agonist pharmacology of neonatal and adult glycine receptor alpha subunits: identification of amino acid residues involved in taurine activation.

1992 • 177 citations

Structure and function of inhibitory glycine receptors

1992 • 162 citations

Functional chloride channels by mammalian cell expression of rat glycine receptor subunit

1989 • 159 citations

Practical Electrophysiological Methods

1993 • 159 citations

Mutation of Glycine Receptor Subunit Creates β-Alanine Receptor Responsive to GABA

1993 • 147 citations

Distinct agonist- and antagonist-binding sites on the glycine receptor

1992 • 132 citations

Antagonism of ligand-gated ion channel receptors: two domains of the glycine receptor alpha subunit form the strychnine-binding site.

1992 • 111 citations

Localization of glycine receptor α1 subunit mRNA-containing neurons in the rat brain: An analysis using in situ hybridization histochemistry

1991 • 107 citations

Localization of the strychnine binding site on the 48-kilodalton subunit of the glycine receptor

1990 • 57 citations

Importance of Arg‐219 for correct biogenesis of α1 homooligomeric glycine receptors

1993 • 36 citations

Glycine receptors: a startling connection

1993 • 19 citations