MANAGEMENT OF SMALL-CELL LUNG CANCER

Reduction by Granulocyte Colony-Stimulating Factor of Fever and Neutropenia Induced by Chemotherapy in Patients with Small-Cell Lung Cancer

1991 • 1,401 citations

Does thoracic irradiation improve survival and local control in limited-stage small-cell carcinoma of the lung? A meta-analysis.

1992 • 802 citations

The World Health Organization Histological Typing of Lung Tumours: Second Edition

1982 • 658 citations

Randomized study of cyclophosphamide, doxorubicin, and vincristine versus etoposide and cisplatin versus alternation of these two regimens in extensive small-cell lung cancer: a phase III trial of the Southeastern Cancer Study Group.

1992 • 532 citations

MEDICAL RESEARCH COUNCIL COMPARATIVE TRIAL OF SURGERY AND RADIOTHERAPY FOR PRIMARY TREATMENT OF SMALL-CELLED OR OAT-CELLED CARCINOMA OF BRONCHUS

1973 • 528 citations

Chemotherapy with or without Radiation Therapy in Limited Small-Cell Carcinoma of the Lung

1987 • 484 citations

Keynote address on biostatistics and data retrieval.

1973 • 476 citations

A randomized trial to evaluate the effect of schedule on the activity of etoposide in small-cell lung cancer.

1989 • 467 citations

Randomized Trial of Cyclophosphamide, Doxorubicin, and Vincristine Versus Cisplatin and Etoposide Versus Alternation of These Regimens in Small-Cell Lung Cancer

1991 • 444 citations

Determinants of improved outcome in small-cell lung cancer: an analysis of the 2,580-patient Southwest Oncology Group data base.

1990 • 385 citations

QUANTAL COMPONENTS OF END‐PLATE POTENTIALS IN THE MYASTHENIC SYNDROME*

1971 • 304 citations

Staging and prognostic factors in small cell lung cancer: a consensus report

1989 • 256 citations

Surgical resection in the management of small cell carcinoma of the lung

1982 • 255 citations

Cancer-Associated Retinopathy (CAR Syndrome) with Antibodies Reacting with Retinal, Optic-Nerve, and Cancer Cells

1989 • 240 citations

Prognostic factors in small-cell carcinoma of the lung: an analysis of 1,521 patients.

1989 • 230 citations

Superiority of Alternating Non-Cross-Resistant Chemotherapy in Extensive Small Cell Lung Cancer

1987 • 227 citations

Chemotherapy Alone or Chemotherapy with Chest Radiation Therapy in Limited Stage Small Cell Lung Cancer

1987 • 225 citations

Histopathologic classification of small cell lung cancer changing concepts and terminology

1988 • 220 citations

Prognostic factors in small cell lung cancer: Multivariate model based on 778 patients treated with chemotherapy with or without irradiation

1987 • 218 citations

Prolonged administration of oral etoposide in patients with relapsed or refractory small-cell lung cancer: a phase II trial.

1990 • 217 citations

The syndrome of inappropriate secretion of antidiuretic hormone (SIADH) in small-cell lung cancer.

1986 • 211 citations

An overview of prognostic factors in small cell lung cancer

1990 • 206 citations

Late intensification chemotherapy with autologous bone marrow transplantation in selected small-cell carcinoma of the lung: a randomized study.

1987 • 204 citations

Gender and Histologic Type Variations in Smoking-Related Risk of Lung Cancer

1992 • 196 citations

Concurrent chemotherapy/radiotherapy for limited small-cell lung carcinoma: a Southwest Oncology Group Study.

1990 • 195 citations

Etoposide (VP-16) and cisplatin: an effective treatment for relapse in small-cell lung cancer.

1985 • 188 citations

The nature of the “oat‐celled sarcoma” of the mediastinum

1926 • 187 citations

Duration of chemotherapy in small cell lung cancer: a Cancer Research Campaign trial

1989 • 170 citations

VP-16-213 monotherapy for remission induction of small cell lung cancer: a randomized trial using three dosage schedules.

1978 • 166 citations

Presenting conditions of 1539 population-based lung cancer patients by cell type and stage in new hampshire and vermont

1985 • 157 citations

Clinical biology of small cell carcinoma: relationship to surgical therapy.

1978 • 152 citations

Canadian multicenter randomized trial comparing sequential and alternating administration of two non-cross-resistant chemotherapy combinations in patients with limited small-cell carcinoma of the lung.

1987 • 146 citations

Role of chemotherapy in small cell lung cancer: a consensus report of the International Association for the Study of Lung Cancer workshop.

1983 • 145 citations

Small-cell carcinoma of the lung: derivation of a prognostic staging system.

1991 • 143 citations

Neurologic, computed cranial tomographic, and magnetic resonance imaging abnormalities in patients with small-cell lung cancer: further follow-up of 6- to 13-year survivors.

1990 • 143 citations

A preliminary report: Concurrent twice-daily radiotherapy plus platinum-etoposide chemotherapy for limited small cell lung cancer

1988 • 142 citations

Cushing's syndrome associated with ectopic corticotropin production and small-cell lung cancer.

1992 • 137 citations

SPECIFICITY OF CALCIUM CHANNEL AUTOANTIBODIES IN LAMBERT-EATON MYASTHENIC SYNDROME

1989 • 133 citations

A randomized comparison of high-dose versus conventional-dose cyclophosphamide, doxorubicin, and vincristine for extensive-stage small-cell lung cancer: a phase III trial of the Southeastern Cancer Study Group.

1987 • 129 citations

Biosynthesis of Vasopressin In Vitro and Ultrastructure of a Bronchogenic Carcinoma

1972 • 127 citations

The role of prophylactic brain irradiation in limited stage small cell lung cancer: Clinical, neuropsychologic, and ct sequelae

1988 • 127 citations

Cisplatin plus etoposide consolidation following cyclophosphamide, doxorubicin, and vincristine in limited small-cell lung cancer.

1988 • 125 citations

Surgical treatment for limited small-cell lung cancer

1991 • 123 citations

Ten-year survival of patients with small-cell lung cancer treated with combination chemotherapy with or without irradiation.

1990 • 118 citations

Autoantibodies Bind Solubilized Calcium Channel-ω-Conotoxin Complexes From Small Cell Lung Carcinoma: A Diagnostic Aid for Lambert-Eaton Myasthenic Syndrome

1989 • 117 citations

Carboplatin (CBDCA, JM-8) and VP-16-213 in previously untreated patients with small-cell lung cancer.

1987 • 114 citations

Primary chemotherapy of brain metastasis in small-cell lung cancer.

1989 • 112 citations

Intensive weekly chemotherapy for the treatment of extensive-stage small-cell lung cancer.

1991 • 112 citations

Significant changes in the distribution of histologic types of lung cancer a review of 4928 cases

1990 • 112 citations

Patients with Small-Cell Lung Cancer Treated with Combination Chemotherapy with or without Irradiation

1985 • 111 citations

Controlled trial of twelve versus six courses of chemotherapy in the treatment of small-cell lung cancer

1989 • 104 citations

Co-trimoxazole prophylaxis during high-dose chemotherapy of small-cell lung cancer.

1985 • 104 citations

A randomized comparison of standard chemotherapy versus alternating chemotherapy and maintenance versus no maintenance therapy for extensive-stage small-cell lung cancer: a phase III study of the Eastern Cooperative Oncology Group.

1990 • 103 citations

The frequency and clinical biology of the ectopic hormone syndromes of small cell carcinoma

1982 • 96 citations

Carboplatin (Paraplatin; JM8) and etoposide (VP-16) as first-line combination therapy for small-cell lung cancer.

1987 • 96 citations

Late neurological complications after prophylactic cranial irradiation in patients with small-cell lung cancer: the Toronto experience.

1990 • 95 citations

Predictors of radiation response in lung cancer.A clinico-pathobiological analysis

1976 • 95 citations

Survival after resection of small cell carcinoma of the bronchus.

1980 • 93 citations

High-dose intensification therapy with autologous bone marrow support for limited small-cell bronchogenic carcinoma.

1986 • 87 citations

Cisplatin/etoposide versus ifosfamide/etoposide combination chemotherapy in small-cell lung cancer: a multicenter German randomized trial.

1987 • 87 citations

Female patients with small cell lung cancer live longer than male patients

1988 • 84 citations

National survey of the pattern of care for carcinoma of the lung

1990 • 82 citations

The importance of surgical and multimodality treatment for small cell bronchial carcinoma

1989 • 77 citations

Histopathologic classification of small cell carcinoma of the lung. Comments based on an interobserver examination

1982 • 76 citations

Bronchogenic Carcinoma with Inappropriate Antidiuretic Activity in Plasma and Tumor

1964 • 74 citations

Long-term survival and toxicity in small cell lung cancer

1984 • 72 citations

Cisplatin and etoposide combination chemotherapy for refractory small cell carcinoma of the lung

1986 • 72 citations

Late intensive combined modality therapy followed by autologous bone marrow infusion in extensive-stage small-cell lung cancer.

1986 • 72 citations

Single-agent chemotherapy trials in small-cell lung cancer, 1970 to 1990: the case for studies in previously treated patients.

1992 • 67 citations

Outcome of patients with small-cell lung cancer: effect of changes in staging procedures and imaging technology on prognostic factors over 14 years.

1990 • 67 citations

High-dose cyclophosphamide in small-cell carcinoma of the lung.

1985 • 65 citations

Prophylactic cranial irradiation and small cell lung cancer

1988 • 64 citations

Mortality and morbidity in long-term surviving patients treated with chemotherapy with or without irradiation for small-cell lung cancer.

1986 • 59 citations

Non-small-cell lung cancer. Major cause of late mortality in patients with small cell lung cancer

1986 • 57 citations

Treatment of limited-stage small-cell lung cancer with cyclophosphamide, doxorubicin, and vincristine with or without etoposide: a randomized trial of the North Central Cancer Treatment Group.

1990 • 57 citations

Effect of tobacco smoking on various histological types of lung cancer

1992 • 56 citations

Etoposide combined with cyclophosphamide plus vincristine compared with doxorubicin plus cyclophosphamide plus vincristine and with high-dose cyclophosphamide plus vincristine in the treatment of small-cell carcinoma of the lung: a randomized trial of the Bristol Lung Cancer Study Group.

1989 • 55 citations

Brain metastases from small cell lung cancer treated with combination chemotherapy

1988 • 55 citations

Intensive weekly chemotherapy for good-prognosis patients with small-cell lung cancer.

1991 • 54 citations

Expression of the Atrial Natriuretic Factor Gene in small Cell Lung Cancer Tumors and Tumor Cell Lines

1990 • 53 citations

Alternating radiotherapy and chemotherapy in 173 consecutive patients with limited small cell lung carcinoma

1990 • 53 citations

Teniposide and etoposide in previously untreated small-cell lung cancer: a randomized study.

1991 • 48 citations

Paraneoplastic syndromes in lung cancer

1992 • 47 citations

Influence of surgical resection prior to chemotherapy on the long-term results in small cell lung cancer. A study of 150 operable patients

1986 • 46 citations

Combination chemotherapy in small cell lung carcinoma: A randomized study of two intensive regimens

1984 • 45 citations

Survival in small cell lung carcinoma after surgery.

1986 • 44 citations

Addition of etoposide to cyclophosphamide, doxorubicin and vincristine for remission induction and survival in patients with small cell lung cancer

1987 • 40 citations

Improvement of long-term survival in extensive small-cell lung cancer.

1988 • 39 citations

Extensive-stage small-cell bronchogenic carcinoma: intensive induction chemotherapy with high-dose cyclophosphamide plus high-dose etoposide.

1985 • 38 citations

Etoposide and cisplatin salvage chemotherapy for small cell lung cancer

1985 • 38 citations

Hyponatremia in small cell lung cancer. Mechanisms not involving inappropriate ADH secretion

1987 • 37 citations

"Salvage" radiation therapy for intrathoracic small cell carcinoma of the lung progressing on combination chemotherapy.

1983 • 37 citations

Prospective study of etoposide scheduling in combination chemotherapy for limited disease small cell lung carcinoma

1991 • 36 citations

Ectopic adrenocorticotrophic (ACTH) syndrome and small cell carcinoma of the lung—assessment of clinical implications in patients on combination chemotherapy

1981 • 35 citations

Bronchogenic Carcinoma

1979 • 35 citations

Single-agent oral etoposide for elderly small cell lung cancer patients

1990 • 34 citations

Small cell lung cancer cell lines secrete predominantly ACTH precursor peptides not ACTH

1989 • 34 citations

Diagnosis and significance of liver metastases in small cell carcinoma of the lung.

1984 • 33 citations

Phase II trial of daily oral VP-16 in refractory small cell lung cancer: a Hoosier Oncology Group study

1990 • 33 citations

Serial Fiberoptic Bronchoscopy during Chemotherapy for Small Cell Carcinoma of the Lung

1978 • 33 citations

Treatment of small-cell lung cancer with an alternating chemotherapy regimen given at weekly intervals: a Southwest Oncology Group pilot study.

1990 • 30 citations

A phase II trial of cisplatin and prolonged administration of oral etoposide in extensive-stage small cell lung cancer

1992 • 28 citations

Ectopic atrial natriuretic peptide production in small cell lung cancer with the syndrome of inappropriate antidiuretic hormone secretion

1991 • 28 citations

Intensive therapy for small-cell lung cancer using carboplatin alternating with cisplatin, ifosfamide, etoposide, mid-cycle vincristine, and radiotherapy.

1991 • 27 citations

Treatment of limited small-cell lung cancer with concurrent etoposide/cisplatin and radiotherapy followed by intensification with high-dose cyclophosphamide: a Southwest Oncology Group study.

1991 • 20 citations

A retrospective study of thirty-two patients with small-cell bronchogenic carcinoma and inappropriate secretion of antidiuretic hormone

1986 • 19 citations

Radiation therapy for chest recurrences following induction chemotherapy in small cell lung cancer

1991 • 18 citations

COMMENTARY: Phase II Trial Design Considerations for Small-Cell Lung Cancer

1992 • 15 citations

High-dose etoposide therapy for extensive small cell lung cancer: a Cancer and Leukemia Group B Study.

1987 • 8 citations

Small-Cell Lung Cancer: Importance of Fiberoptic Bronchoscopy in the Evaluation of Complete Remission

1989 • 8 citations