Prophylactic cranial irradiation and small cell lung cancer

Therapeutic irradiation and brain injury

1980 • 985 citations

The palliation of brain metastases: Final results of the first two studies by the radiation therapy oncology group

1980 • 968 citations

Immunocompromised animal models for the study of antibiotic combinations.

1986 • 291 citations

Lung Cancer: Progress in Therapeutic Research

1979 • 253 citations

Sensory neuronopathy and small cell lung cancer

1986 • 236 citations

Small cell lung cancer 1973–1983: Early progress and recent obstacles

1984 • 219 citations

A randomized combined modality trial in small cell carcinoma of the lung comparison of combination chemotherapy-radiation therapy versus cyclophosphamide-radiation therapy effects of maintenance chemotherapy and prophylactic whole brain irradiation

1980 • 210 citations

Randomized trial of radiotherapy to the thorax in limited small-cell carcinoma of the lung treated with multiagent chemotherapy and elective brain irradiation: a preliminary report.

1984 • 206 citations

Neurologic, neuropsychologic, and computed cranial tomography scan abnormalities in 2- to 10-year survivors of small-cell lung cancer.

1985 • 194 citations

Risk of brain metastasis from small cell carcinoma of the lung related to length of survival and prophylactic irradiation.

1981 • 153 citations

Role of prophylactic cranial irradiation in prevention of central nervous system metastases in small cell lung cancer

1983 • 126 citations

Central nervous system metastases in small cell bronchogenic carcinoma.

1978 • 126 citations

Neurotoxicity in long-term survivors of small cell lung cancer

1986 • 115 citations

Follow-up neurological evaluation in patients with small cell lung carcinoma treated with prophylactic cranial irradiation and chemotherapy

1981 • 109 citations

Value of prophylactic cranial irradiation given at complete remission in small cell lung carcinoma.

1983 • 109 citations

Prophylactic irradiation in bronchogenic small cell anaplastic carcinoma. A comparative trial of localized versus extensive radiotherapy including prophylactic brain irradiation in patients receiving combination chemotherapy

1980 • 109 citations

Role of radiation therapy in small cell anaplastic carcinoma of the lung.

1983 • 107 citations

Metastatic patterns in small-cell lung cancer: correlation of autopsy findings with clinical parameters in 537 patients.

1987 • 103 citations

Should initial treatment of small cell carcinoma include systemic chemotherapy and brain irradiation?

1973 • 97 citations

Low dose elective brain irradiation in small cell carcinoma of the lung

1979 • 93 citations

Prophylactic cranial irradiation in patients with inoperable carcinoma of the lung.Preliminary report of a cooperative trial

1978 • 89 citations

Comparison of symptomatic and prophylactic irradiation of brain metastases from oat cell carcinoma of the lung

1981 • 86 citations

Intracranial metastases in small cell carcinoma of the lung prognostic aspects

1983 • 84 citations

Thoracic and elective brain irradiation with concomitant or delayed multiagent chemotherapy in the treatment of localized small cell carcinoma of the lung: A randomized prospective study by the southeastern cancer study group

1981 • 80 citations

Anticerebellar antibodies in serum and cerebrospinal fluid of a patient with oat cell carcinoma of the lung and paraneoplastic cerebellar degeneration

1986 • 78 citations

“Total” Therapy for Small Cell Carcinoma of the Lung

1978 • 74 citations

Long-term survival and toxicity in small cell lung cancer

1984 • 72 citations

Central nervous system prophylactic treatment for childhood leukemia: Neuropsychological outcome studies

1986 • 72 citations

The effect of CNS metastases on the survival of patients with small cell cancer of the lung

1983 • 72 citations

Prospective evaluation of changes in computed cranial tomography in patients with small cell lung carcinoma treated with chemotherapy and prophylactic cranial irradiation.

1984 • 71 citations

Lung Cancer: Basic and Clinical Aspects

1986 • 66 citations

Prophylactic versus no brain irradiation in regional small cell lung carcinoma

1985 • 65 citations

Results of whole-brain irradiation for metastases from small cell carcinoma of the lung.

1980 • 64 citations

Mortality and morbidity in long-term surviving patients treated with chemotherapy with or without irradiation for small-cell lung cancer.

1986 • 59 citations

A case for preplanned thoracic and prophylactic whole brain radiation therapy in limited small-cell lung cancer.

1981 • 59 citations

Morbidity in long-term survivors of small cell carcinoma of the lung

1984 • 56 citations

Morbidity of cranial relapse in small cell lung cancer and the impact of radiation therapy

1987 • 56 citations

Brain metastases from small cell lung cancer treated with combination chemotherapy

1988 • 55 citations

Improved quality of life of patients with small-cell carcinoma of the lung by elective irradiation of the brain

1982 • 53 citations

Social consequences of brain or liver relapse in small cell carcinoma of the bronchus

1985 • 52 citations

Prophylactic cranial irradiation in small cell carcinoma of the lung.

1982 • 50 citations

Prophylactic irradiation in bronchogenic small cell anaplastic carcinoma

1980 • 45 citations

Neurologic dysfunction in patients treated for small cell carcinoma of the lung: A clinical and radiological study

1986 • 43 citations

Patterns of failure in small cell carcinoma of the lung

1982 • 41 citations

What is the lowest effective biologic dose for prophylactic cranial irradiation?

1985 • 35 citations

Disturbing central nervous system complications following combination chemotherapy and prophylactic whole-brain irradiation in patients with small cell lung cancer.

1985 • 29 citations

Treatment of small cell carcinoma of lung with combined high dose mediastinal irradiation, whole brain prophylaxis and chemotherapy

1981 • 29 citations

Risk factors in long‐term sequelae of central nervous system prophylaxis in successfully treated children with acute lymphocytic leukemia

1985 • 26 citations

Changes in the relative risk and sites of central nervous system metastasis with effective combined chemotherapy and radiation therapy for small cell carcinoma of the lung*

1983 • 26 citations

Glycoconjugates in nervous tissue and small cell lung cancer share immunologically cross-reactive carbohydrate determinants

1986 • 23 citations

Extensive disease small cell carcinoma of the lung. Trial of non-cross resistant chemotherapy and consolidation radiotherapy

1982 • 22 citations

Prognostic Factors in Small Cell Lung Cancer: An Analysis of 874 Consecutive Patients

1986 • 22 citations

Survival of patients with pleural involvement by breast carcinoma

1983 • 18 citations

Short course prophylactic cranial irradiation for small cell lung cancer

1985 • 17 citations

Etoposide, cisplatin and doxorubicin in patients with small cell lung cancer: Tumor response and long term survival

1986 • 17 citations

Effects of brain irradiation and chemotherapy on myelosuppression in small-cell lung cancer.

1986 • 15 citations