An immunogenetic analysis of the T-cell recognition of the major house dust mite allergen Der p 2: identification of high- and low-responder HLA-DQ alleles and localization of T-cell epitopes.

T-Lymphocyte Recognition of Antigen in Association with Gene Products of the Major Histocompatibility Complex

1985 • 942 citations

Sequence analysis of cDNA coding for a major house dust mite allergen, Der p 1. Homology with cysteine proteases.

1988 • 469 citations

The natural immune response to inhaled soluble protein antigens involves major histocompatibility complex (MHC) class I-restricted CD8+ T cell-mediated but MHC class II-restricted CD4+ T cell-dependent immune deviation resulting in selective suppression of immunoglobulin E production.

1993 • 317 citations

Regulation of IgE Synthesis

1984 • 301 citations

T cell activation-inducing epitopes of the house dust mite allergen Der p I. Proliferation and lymphokine production patterns by Der p I-specific CD4+ T cell clones.

1992 • 244 citations

Monoclonal immunoassay for major dust mite () allergens, I and I, and quantitative analysis of the allergen content of mite and house dust extracts

1987 • 219 citations

Sequence analysis of cDNA coding for a major house dust mite allergen, Der f I

1991 • 215 citations

HLA-DQ is epistatic to HLA-DR in controlling the immune response to schistosomal antigen in humans

1987 • 212 citations

The Atomic Mobility Component of Protein Antigenicity

1985 • 201 citations

HLA‐DR and HLA‐DP genotypes and immunoglobulin E responses to common major allergens

1994 • 158 citations

Isolation of cDNA Coding for the Major Mite Allergen <i>Der </i><i>p</i> II by IgE Plaque Immunoassay

1990 • 151 citations

The Specificity and Regulation of T-Cell Responsiveness to Allergens

1991 • 135 citations

T cell epitopes of house dust mite major allergen Der p II.

1993 • 124 citations

Skin tests and histamine release with P-depleted body extracts and purified P

1988 • 110 citations

Immunological suppression by human CD8+ T cells is receptor dependent and HLA-DQ restricted.

1991 • 103 citations

Analysis of human T cell responses to the group II allergen of Dermatophagoides species: Localization of major antigenic sites

1993 • 94 citations

HLA-linked nonresponsiveness to Cryptomeria japonica pollen antigen. I. Nonresponsiveness is mediated by antigen-specific suppressor T cell.

1987 • 88 citations

IgE and IgG binding of peptides expressed from fragments of cDNA encoding the major house dust mite allergen Der p I.

1991 • 87 citations

Peptide-induced nonresponsiveness of HLA-DP restricted human T cells reactive with spp. (house dust mite)

1992 • 79 citations

T cell responses to the purified major allergens from the house dust mite

1992 • 64 citations

HLA-DR4-associated nonresponsiveness to mountain-cedar allergen

1992 • 57 citations

An immunogenetic analysis of T-cell reactive regions on the major allergen from the house dust mite, Der p I, with recombinant truncated fragments

1994 • 45 citations

DR7 and DQ2 are positively associated with immunoglobulin-E response to the main antigen of olive pollen (Ole e I) in allergic patients

1993 • 45 citations

Immune reactivity to Der p I and Der p II in house dust mite sensitive patients attending paediatric and adult allergy clinics

1994 • 37 citations

Frequency of DPB1 ∗0401 is significantly decreased in patients with allergic asthma in a Mulatto population

1991 • 32 citations

Identification of an HLA-DQ2 peptide binding motif and HLA-DPw3-bound self-peptide by pool sequencing

1994 • 30 citations

T lymphocyte subset abnormalities and HLA antigens in scleroderma (systemic sclerosis).

1989 • 21 citations

Role of HLA Class II Products in Proliferative T‐Lymphocyte Responses to PPD

1984 • 19 citations

Newly generated IgE antibodies to in children are directed against components distinct from I and II

1991 • 12 citations