A role for the p34cdc2 kinase and phosphatases in the regulation of phosphorylation and disassembly of lamin B2 during the cell cycle.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Universal control mechanism regulating onset of M-phase

1990 • 2,882 citations

Okadaic acid: a new probe for the study of cellular regulation

1990 • 1,396 citations

Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis

1989 • 1,237 citations

The nuclear lamina is a meshwork of intermediate-type filaments

1986 • 957 citations

The nuclear envelope lamina is reversibly depolymerized during mitosis

1980 • 956 citations

Isolation of a human cyclin cDNA: Evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2

1989 • 920 citations

Purified maturation-promoting factor contains the product of a Xenopus homolog of the fission yeast cell cycle control gene cdc2+

1988 • 885 citations

Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism

1989 • 848 citations

Homologies in both primary and secondary structure between nuclear envelope and intermediate filament proteins

1986 • 836 citations

In vitro disassembly of the nuclear lamina and M phase-specific phosphorylation of lamins by cdc2 kinase

1990 • 783 citations

cdc2 protein kinase is complexed with both cyclin A and B: Evidence for proteolytic inactivation of MPF

1989 • 666 citations

Mutations of phosphorylation sites in lamin A that prevent nuclear lamina disassembly in mitosis

1990 • 642 citations

Purification of maturation-promoting factor, an intracellular regulator of early mitotic events.

1988 • 640 citations

Protein phosphatases come of age

1989 • 616 citations

Functional Organization Of The Nuclear Envelope

1988 • 593 citations

Immunocytochemical localization of the major polypeptides of the nuclear pore complex-lamina fraction. Interphase and mitotic distribution.

1978 • 527 citations

The nuclear lamins

1986 • 488 citations

Reversible tyrosine phosphorylation of cdc2: Dephosphorylation accompanies activation during entry into mitosis

1989 • 453 citations

Continuous tissue culture cell lines derived from chemically induced tumors of Japanese quail

1977 • 443 citations

Identification of cell cycle-regulated phosphorylation sites on nuclear lamin C

1990 • 425 citations

The fission yeast cdc2/cdc13/suc1 protein kinase: Regulation of catalytic activity and nuclear localization

1989 • 392 citations

Production of large numbers of mitotic mammalian cells by use of the reversible microtubule inhibitor Nocodazole

1980 • 389 citations

A cell free system to study reassembly of the nuclear envelope at the end of mitosis

1986 • 382 citations

Purification of MPF from starfish: Identification as the H1 histone kinase p34cdc2 and a possible mechanism for its periodic activation

1989 • 366 citations

Phosphorylation of the nuclear lamins during interphase and mitosis.

1985 • 354 citations

Disassembly of the nucleus in mitotic extracts: Membrane vesicularization, lamin disassembly, and chromosome condensation are independent processes

1987 • 349 citations

Teratocarcinoma stem cells and early mouse embryos contain only a single major lamin polypeptide closely resembling lamin B

1987 • 347 citations

Identification of major nucleolar proteins as candidate mitotic substrates of cdc2 kinase

1990 • 344 citations

THE NUCLEUS: STRUCTURE, FUNCTION, AND DYNAMICS

1987 • 333 citations

Fission yeast p13 blocks mitotic activation and tyrosine dephosphorylation of the Xenopus cdc2 protein kinase

1989 • 327 citations

Purified maturation promoting factor phosphorylates pp60c-src at the sites phosphorylated during fibroblast mitosis

1989 • 319 citations

Activation at M-phase of a protein kinase encoded by a starfish homologue of the cell cycle control gene cdc2+

1988 • 314 citations

Dephosphorylation and activation of Xenopusp34cdc2 protein kinase during the cell cycle

1989 • 300 citations

Myc oncoproteins are phosphorylated by casein kinase II.

1989 • 287 citations

Phosphorylation of RNA polymerase by the murine homologue of the cell-cycle control protein cdc2

1989 • 270 citations

Mammalian growth-associated H1 histone kinase: a homolog of cdc2+/CDC28 protein kinases controlling mitotic entry in yeast and frog cells.

1989 • 265 citations

A 60 kd cdc2-associated polypeptide complexes with the E1A proteins in adenovirus-infected cells

1989 • 262 citations

Altered phosphorylation and activation of PP60c-src during fibroblast mitosis

1988 • 249 citations

Phosphorylation of large tumour antigen by cdc2 stimulates SV40 DNA replication

1989 • 242 citations

Mitosis-specific phosphorylation of p60c-src by p34cdc2-associated protein kinase

1989 • 239 citations

Nuclear lamins and cytoplasmic intermediate filament proteins: A growing multigene family

1987 • 235 citations

V-myc- and c-myc-encoded proteins are associated with the nuclear matrix.

1985 • 222 citations

Mutations in the nuclear lamin proteins resulting in their aberrant assembly in the cytoplasm.

1988 • 217 citations

Differential expression of nuclear lamin proteins during chicken development.

1987 • 205 citations

Okadaic acid mimics the action of insulin in stimulating protein kinase activity in isolated adipocytes. The role of protein phosphatase 2a in attenuation of the signal.

1990 • 183 citations

Protein kinase C mediates platelet-derived growth factor-induced tyrosine phosphorylation of p42.

1988 • 166 citations

Differential Phosphorylation of c-Abl in Cell Cycle Determined by cdc 2 Kinase and Phosphatase Activity

1990 • 157 citations

Activation of human CDC2 protein as a histone H1 kinase is associated with complex formation with the p62 subunit.

1989 • 148 citations

Involvement of protein phosphatases 1 and 2A in the control of M phase-promoting factor activity in starfish.

1989 • 141 citations

The nuclear lamin protein family in higher vertebrates. Identification of quantitatively minor lamin proteins by monoclonal antibodies.

1986 • 134 citations

Autoimmune response directed against conserved determinants of nuclear envelope proteins in a patient with linear scleroderma.

1983 • 133 citations

Drosophila nuclear lamin precursor Dm0 is translated from either of two developmentally regulated mRNA species apparently encoded by a single gene [published erratum appears in J Cell Biol 1988 Jun;106(6):2225]

1988 • 130 citations

Cloning and sequencing of cDNA clones encoding chicken lamins A and B1 and comparison of the primary structures of vertebrate A- and B-type lamins

1989 • 115 citations

The fates of chicken nuclear lamin proteins during mitosis: evidence for a reversible redistribution of lamin B2 between inner nuclear membrane and elements of the endoplasmic reticulum.

1988 • 110 citations

A role for the p34cdc2 kinase and phosphatases in the regulation of phosphorylation and disassembly of lamin B2 during the cell cycle.

1991 • 108 citations

A second higher vertebrate B-type lamin

1989 • 102 citations

A human T lymphoblastic cell line lacks lamins A and C.

1987 • 93 citations

Nuclear Function and Organization: The Potential of Immunochemical Approaches

1988 • 79 citations

A fractionated cell-free system for analysis of prophase nuclear disassembly.

1986 • 75 citations

Mammalian Growth-Associated H1 Histone Kinase: a Homolog of cdc2⁺/CDC28 Protein Kinases Controlling Mitotic Entry in Yeast and Frog Cells

1989 • 70 citations

V-myc- and c-myc-Encoded Proteins Are Associated with the Nuclear Matrix

1985 • 69 citations

Establishment of tumor cell lines cultured from chickens with avian lymphoid leukosis.

1974 • 59 citations