Sera from patients with heparin-induced thrombocytopenia generate platelet-derived microparticles with procoagulant activity: an explanation for the thrombotic complications of heparin-induced thrombocytopenia

Mechanism by which cyanine dyes measure membrane potential in red blood cells and phosphatidylcholine vesicles

1974 • 949 citations

A diagnostic test for heparin-induced thrombocytopenia

1986 • 706 citations

Complement proteins C5b-9 cause release of membrane vesicles from the platelet surface that are enriched in the membrane receptor for coagulation factor Va and express prothrombinase activity.

1988 • 663 citations

Assembly of the Platelet Prothrombinase Complex Is Linked to Vesiculation of the Platelet Plasma Membrane

1989 • 597 citations

Antibodies from patients with heparin-induced thrombocytopenia/thrombosis are specific for platelet factor 4 complexed with heparin or bound to endothelial cells.

1994 • 557 citations

Heparin-induced thrombocytopenia: laboratory studies

1988 • 423 citations

Immune Endothelial-Cell Injury in Heparin-Associated Thrombocytopenia

1987 • 390 citations

Determinants of donor platelet variability when testing for heparin-induced thrombocytopenia.

1992 • 190 citations

Heparin‐induced thrombocytopenia and thrombosis: clinical and laboratory studies

1993 • 182 citations

Platelet procoagulant activity: physiological significance and mechanisms of exposure

1991 • 177 citations

Heparin-induced thrombocytopenia

2013 • 146 citations

Vesiculation of platelets during in vitro aging

1991 • 145 citations

Contribution of platelet microparticle formation and granule secretion to the transmembrane migration of phosphatidylserine.

1993 • 143 citations

Investigation of the mechanisms of monoclonal antibody-induced platelet activation

1991 • 118 citations

Drug-Induced Platelet Destruction

1982 • 106 citations

Molecular characterization of quinine/quinidine drug-dependent antibody platelet interaction using monoclonal antibodies

1985 • 94 citations

Characteristics of quinine- and quinidine-induced antibodies specific for platelet glycoproteins IIb and IIIa

1991 • 89 citations

Characterization of the binding domains on platelet glycoproteins Ib-IX and IIb/IIIa complexes for the quinine/quinidine-dependent antibodies

1991 • 80 citations

Drug-Antibody-Platelet Interaction in Quinine- and Quinidine-induced Thrombocytopenia

1982 • 70 citations

Detection of drug‐dependent, platelet‐reactive antibodies by antigen‐ capture ELISA and flow cytometry

1990 • 69 citations

Quinine‐ and quinidine platelet antibodies can react with GPIIb/IIIa

1987 • 46 citations

Analysis of Platelet Factor 3 in Platelet Concentrates Stored for Transfusion

1986 • 35 citations

A new lupus anticoagulant neutralization test based on platelet‐derived vesicles

1992 • 30 citations

An enzyme-linked immunosorbent assay for the evaluation of thrombocytopenia induced by heparin.

1985 • 25 citations

Immune endothelial-cell injury in heparin-associated thrombocytopenia

1988 • 22 citations

Correlation of a quinidine-induced platelet-specific antibody with development of thrombocytopenia

1985 • 15 citations

Determination of platelet factor 3 in whole blood by a chromogenic peptide substrate assay

1980 • 5 citations