Role of DNA Repair in Aging

Thomas, Springfield, Illinois

1965 • 2,935 citations

Principles of Animal Taxonomy

1961 • 2,050 citations

The Major Features of Evolution.

1954 • 2,019 citations

Defective Repair Replication of DNA in Xeroderma Pigmentosum

1968 • 1,739 citations

Rate of depurination of native deoxyribonucleic acid

1972 • 1,488 citations

THE DISAPPEARANCE OF THYMINE DIMERS FROM DNA: AN ERROR-CORRECTING MECHANISM

1964 • 987 citations

THE MAINTENANCE OF THE ACCURACY OF PROTEIN SYNTHESIS AND ITS RELEVANCE TO AGEING

1963 • 950 citations

Correlation Between Deoxyribonucleic Acid Excision-Repair and Life-Span in a Number of Mammalian Species

1974 • 738 citations

Time, cells, and aging

1962 • 553 citations

Cellular senescence and DNA synthesis

1973 • 537 citations

Altered Enzymes in Ageing Human Fibroblasts

1972 • 408 citations

Nutrition and Longevity in the Rat

1960 • 319 citations

Endonuclease from Micrococcus luteus Which Has Activity Toward Ultraviolet-Irradiated Deoxyribonucleic Acid: Purification and Properties

1970 • 272 citations

Ageing : the biology of senescence

1964 • 253 citations

Repair Replication, Unscheduled DNA Synthesis, and the Repair of Mammalian DNA

1969 • 242 citations

Effects of Radiation on Polynucleotides

1972 • 225 citations

Thermal Enhancement of Ultraviolet Mutability in a tif-1 uvrA Derivative of Escherichia coli B/r: Evidence That Ultraviolet Mutagenesis Depends upon an Inducible Function

1974 • 219 citations

Normal and Defective Repair of Damaged DNA in Human Cells: A Sensitive Assay Utilizing the Photolysis of Bromodeoxyuridine

1971 • 212 citations

Enzymatic Repair of DNA

1975 • 211 citations

The Photochemistry, Photobiology, and Repair of Polynucleotides

1968 • 206 citations

Age-Associated Changes in the DNA of Mouse Tissue

1971 • 203 citations

Nutrition and Longevity in the Rat

1960 • 184 citations

ABSENCE OF EXCISION OF ULTRAVIOLET‐INDUCED CYCLOBUTANE DIMERS IN XERODERMA PIGMENTOSUM*

1970 • 174 citations

DNA Polymerase Required for Rapid Repair of X-ray—Induced DNA Strand Breaks in vivo

1971 • 160 citations

Preferential DNA Repair in Human Cells

1974 • 144 citations

Error Theory and Ageing in Human Diploid Fibroblasts

1972 • 135 citations

Inactive Enzyme Molecules in Aging Mice: Liver Aldolase

1973 • 131 citations

Genetic Concepts and Neoplasia

1971 • 129 citations

Photoreactivating enzyme from human leukocytes

1974 • 127 citations

Deficient DNA Repair in Human Progeroid Cells

1973 • 126 citations

DNA repair in late-passage human cells

1976 • 117 citations

Postreplication repair of DNA in mammalian cells

1974 • 114 citations

Inactive enzyme molecules in aging organisms. Nematode fructose 1,6-diphosphate aldolase

1973 • 114 citations

Physiological Aspects of Aging in Man

1961 • 109 citations

ENZYMATIC REPAIR OF DNA, I. PURIFICATION OF TWO ENZYMES INVOLVED IN THE EXCISION OF THYMINE DIMERS FROM ULTRAVIOLET-IRRADIATED DNA

1969 • 101 citations

Excision repair (dimer excision, strand breakage and repair replication) in primary cultures of eukaryotic (bovine) cells

1972 • 98 citations

Mistranslation and Ageing in Neurospora

1970 • 98 citations

DNA photoreactivating enzyme from placental mammals. Origin and characteristics

1974 • 94 citations

The Role of DNA Repair in Aging of Cultured Fibroblasts from Xeroderma Pigmentosum and Normals

1971 • 93 citations

Xeroderma pigmentosum cells contain low levels of photoreactivating enzyme.

1975 • 90 citations

The production of mucosal ulceration in the rabbit gut by intra‐arterial injection of microspheres

1970 • 86 citations

DNA repair in human progeroid cells

1974 • 85 citations

Is the ability to repair damage to DNA related to the proliferative capacity of a cell? The rejoining of X-ray-produced strand breaks

1973 • 83 citations

An inquiry concerning growth, disease and ageing

1968 • 83 citations

Photoreactivation in animal cells.

1970 • 80 citations

Purification and some properties of a mammalian repair endonuclease

1974 • 76 citations

Altered enzyme molecules in senescent organisms: mouse muscle aldolase

1973 • 72 citations

Age-dependent excision repair of damaged thymine from γ-irradiated DNA by isolated nuclei from human fibroblasts

1975 • 72 citations

Ultraviolet-Induced Repair Replication in Aging Diploid Human Cells (WI-38)

1973 • 67 citations

Formation and Rejoining of DNA Strand Breaks in Irradiated Neurons: In vivo

1972 • 66 citations

THE ROLES OF GENETIC RECOMBINATION AND DNA POLYMERASE IN THE REPAIR OF DAMAGED DNA

1971 • 61 citations

Repair of X-ray damage in aging WI-38 cells

1974 • 61 citations

RESPONSE OF HUMAN SKIN TO ULTRAVIOLET LIGHT

1968 • 59 citations

Repair of Chemical Damage to Human DNA

1973 • 58 citations

Exogenous DNA polymerase-catalysed incorporation of deoxyribonucleotide monophosphates in nuclei of fixed mouse-brain cells *1Changes associated with age and X-irradiation

1971 • 55 citations

Repair of DNA strand breaks after gamma-irradiation of protoplasts isolated from cultured wild carrot cells

1975 • 52 citations

Quantitative Changes in Unscheduled DNA Synthesis in Rat Muscle Cells after Differentiation

1971 • 52 citations

[Cells and aging].

1969 • 50 citations

In Vivo Restitution of the DNA Structure in Gamma Irradiated Rabbit Retinas

1973 • 49 citations

Repair of DNA in mammalian cells

1974 • 47 citations

Redundancy of information content in the genome of mammalian species as a protective mechanism determining aging rate

1973 • 41 citations

DNA Repair Processes in Mammals

2015 • 35 citations

Fission Track Dating of Archaeological Materials from Japan

1971 • 32 citations

Excision repair of DNA base damage

1974 • 31 citations

Repair Replication after U.V.-irradiation in Rodent Cell-lines of Different Sensitivity

1973 • 31 citations

Excision-Repair in Primary Cultures of Mouse Embryo Cells and Its Decline in Progressive Passages and Established Cell Lines

1975 • 30 citations

The action of ultraviolet light on mammalian cells.

1970 • 30 citations

A Model for Aging Based on Differential Repair of Somatic Mutational Damage

1974 • 29 citations

Relationships Among Repair, Mutagenesis, and Survival: Overview

1975 • 27 citations

Aging: alteration of DNA-protein information.

1973 • 27 citations

Aging: Alteration of DNA-Protein Information

1973 • 25 citations

Endocrines and Aging

1977 • 21 citations

Protein turnover in relation to Orgel's error theory of ageing

1972 • 20 citations

Late Somatic Effects of Ionizing Radiation

1969 • 19 citations

Radioprotective stereostructure-activity study of cis- and trans-2-mercaptocyclobutylamine analogs and homologs of 2-mercaptoethylamine

1975 • 14 citations

Unscheduled DNA synthesis and cellular recovery in various mammalian cell lines.

1972 • 8 citations