The Photochemistry, Photobiology, and Repair of Polynucleotides

Discontinuities in the DNA synthesized in an Excision-defective strain of Escherichia coli following ultraviolet irradiation

1968 • 1,089 citations

THE DISAPPEARANCE OF THYMINE DIMERS FROM DNA: AN ERROR-CORRECTING MECHANISM

1964 • 987 citations

Enzymatic Synthesis of Deoxyribonucleic Acid

1961 • 758 citations

Reconstruction in vivo of Irradiated Escherichia coli Deoxyribonucleic Acid; the Rejoining of Broken Pieces

1966 • 727 citations

RELEASE OF ULTRAVIOLET LIGHT-INDUCED THYMINE DIMERS FROM DNA IN E. COLI K-12

1964 • 710 citations

MUTANTS OF ESCHERICHIA COLI K-12 DEFECTIVE IN DNA REPAIR AND IN GENETIC RECOMBINATION

1966 • 635 citations

Pyrimidine dimers in ultraviolet-irradiated DNA's

1966 • 569 citations

THREE LOCI IN ESCHERICHIA COLI K-12 THAT CONTROL THE EXCISION OF PYRIMIDINE DIMERS AND CERTAIN OTHER MUTAGEN PRODUCTS FROM DNA

1966 • 566 citations

DNA Repair and Genetic Recombination: Studies on Mutants of Escherichia coli Defective in These Processes

1966 • 554 citations

Evidence for repair-replication of ultraviolet damaged DNA in bacteria

1964 • 510 citations

Isolation and identification of the irradiation product of thymine

1960 • 474 citations

Photochemistry of Proteins and Nucleic Acids

1964 • 361 citations

Cyclobutane-Type Pyrimidine Dimers in Polynucleotides

1966 • 351 citations

Thymine Dimers and Inhibition of DNA Synthesis by Ultraviolet Irradiation of Cells

1963 • 344 citations

Radiation-Induced Mutations and Their Repair

1966 • 330 citations

EVIDENCE THAT ULTRAVIOLET-INDUCED THYMINE DIMERS IN DNA CAUSE BIOLOGICAL DAMAGE

1962 • 318 citations

Evidence for Excision of Ultraviolet-Induced Pyrimidine Dimers from the DNA of Human Cells In Vitro

1968 • 304 citations

Enzymatic breakage and joining of deoxyribonucleic acid, I. Repair of single-strand breaks in DNA by an enzyme system from Escherichia coli infected with T4 bacteriophage.

1967 • 284 citations

Physical Processes in Radiation Biology

1964 • 284 citations

Regulation of Nucleic Acid and Protein Biosynthesis

1967 • 274 citations

Thymine Photoproducts but not Thymine Dimers Found in Ultraviolet-Irradiated Bacterial Spores

1965 • 253 citations

A radiation-sensitive mutant of Escherichia coli

1958 • 251 citations

Physical Processes in Radiation Biology

1966 • 239 citations

Formation of covalent circles of lambda DNA by E. coli extracts.

1967 • 229 citations

Disappearance of thymine photodimer in ultraviolet irradiated DNA upon treatment with a photoreactivating enzyme from Baker's yeast

1962 • 222 citations

GROWTH, RESPIRATION, AND NUCLEIC ACID SYNTHESIS IN ULTRAVIOLET-IRRADIATED AND IN PHOTOREACTIVATED ESCHERICHIA COLI

1953 • 198 citations

Mutants of phage T4 with increased sensitivity to ultraviolet

1963 • 197 citations

Abnormal metabolic response to ultraviolet light of a recombination deficient mutant of Escherichia coli K12

1966 • 193 citations

Repair of Deoxyribonucleic Acid in Haemophilus influenzae I. X-Ray Sensitivity of Ultraviolet-sensitive Mutants and Their Behavior as Hosts to Ultraviolet-irradiated Bacteriophage and Transforming Deoxyribonucleic Acid

1968 • 191 citations

ULTRAVIOLET‐INDUCED LETHALITY AND REVERSION TO PROTOTROPHY IN ESCHERICHIA COLI STRAINS WITH NORMAL AND REDUCED DARK REPAIR ABILITY

1965 • 180 citations

Nature of the Photoreactivable Ultra-Violet Lesion in Deoxyribonucleic Acid

1963 • 179 citations

Enzymatic joining of DNA strands: a novel reaction of diphosphopyridine nucleotide.

1967 • 175 citations

The Induction of Thymine Dimers in Ultraviolet-Irradiated Mammalian Cells

1965 • 168 citations

Repair Replication in HeLa Cells after Large Doses of X-irradiation

1967 • 157 citations

Physical changes and mutagenesis

1964 • 157 citations

Effects of ultraviolet radiation on macromolecular synthesis in Escherichia coli

1966 • 148 citations

Pyrimidine dimers in UV-irradiated poly dI:dC.

1965 • 136 citations

Reactivation After Photobiological Damage

1966 • 136 citations

Sensitized photodimerization of thymine in DNA.

1967 • 133 citations

Photochemistry of thymine dimers

1962 • 128 citations

THE U.V. SENSITIVITY OF BACTERIA: ITS RELATION TO THE DNA REPLICATION CYCLE

1966 • 128 citations

The enzymatic repair of DNA. I. Formation of circular lambda-DNA.

1967 • 127 citations

ULTRAVIOLET LIGHT INDUCED LINKING OF DEOXYRIBONUCLEIC ACID STRANDS AND ITS REVERSAL BY PHOTOREACTIVATING ENZYME

1961 • 126 citations

The chemical nature of photoreactivable lesions in DNA.

1965 • 122 citations

Repair replication of DNA in bacteria: Irrelevance of chemical nature of base defect

1965 • 122 citations

Evidence for Two Mechanisms of Photoreactivation in Escherichia coli B

1965 • 118 citations

Ultraviolet inactivation of DNA primer activityI. Effects of different wavelengths and doses

1963 • 116 citations

Ultraviolet inactivation of DNA primer activity

1963 • 116 citations

Diphosphopyridine nucleotide: a cofactor for the polynucleotide-joining enzyme from Escherichia coli.

1967 • 114 citations

A host effect on bacteriophage survival after ultraviolet irradiation

1960 • 114 citations

Comparison of ultraviolet sensitivity of Bacillus subtilis bacteriophage SPO2 and its infectious DNA

1965 • 110 citations

Isolation and properties of isomeric thymine dimers

1966 • 108 citations

Photoreactivating-enzyme activity in metazoa.

1967 • 107 citations

Effects of ultraviolet light on thymidine dinucleotide and polynucleotide

1963 • 106 citations

The Ultraviolet Photochemistry and Photobiology of Vegetative Cells and Spores of Bacillus megaterium

1968 • 103 citations

Effects of ultraviolet light on thymidine dinucleotide and polynucleotide

1963 • 102 citations

The resistance of Micrococcus radiodurans to ultraviolet radiation

1966 • 97 citations

Repair of damage induced by a monofunctional alkylating agent in a transformable, ultraviolet-sensitive strain of Bacillus subtilis

1965 • 94 citations

IDENTIFICATION OF ULTRAVIOLET‐INDUCED THYMINE DIMERS IN DNA BY ABSORBANCE MEASUREMENTS

1963 • 90 citations

Studies on the Yeast Photoreactivating Enzyme

1966 • 89 citations

The influence of 5-bromodeoxyuridine substitution on UV sensitivity, host-cell reactivation, and photoreactivation in T1 and P22H5

1961 • 86 citations

The action spectrum for the reversal of the dimerization of thymine induced by ultraviolet light

1961 • 81 citations

The molecular basis for radiation effects on cells.

1966 • 80 citations

Regulation of nucleic acid and protein biosyntheis

1967 • 80 citations

Effects of ultraviolet light on the template properties of polycytidylic acid

1965 • 79 citations

Suppression of hydrate and dimer formation in ultraviolet-irradiated poly (A + U) relative to poly U

1966 • 76 citations

Overlap of Photoreactivation and Liquid Holding Recovery in Escherichia coli B

1964 • 76 citations

Photoinduced DNA-Protein Cross-Links and Bacterial Killing: A Correlation at Low Temperatures

1967 • 76 citations

Kinetics of Thymine Photodimerization in DNA

1963 • 74 citations

The ultraviolet photochemistry of cytidylyl-(3′-5′)-cytidine

1965 • 74 citations

Nuclease-resistant sequences in ultraviolet-irradiated deoxyribonucleic acid

1964 • 72 citations

The resistance of Micrococcus radiodurans to ultraviolet radiation

1964 • 72 citations

KINETICS OF DIMER FORMATION AND PHOTOHYDRATION IN ULTRAVIOLET‐IRRADIATED POLYURIDYLIC ACID

1963 • 72 citations

Comparative study of some properties of bacteriophage T4D irradiated with monochromatic ultraviolet light

1962 • 72 citations

The range of action of genes controlling radiation sensitivity in Escherichia coli

1965 • 71 citations

STUDY OF PYRIMIDINE DIMERS IN MAMMALIAN CELLS SURVIVING LOW DOSES OF ULTRAVIOLET RADIATION*

1967 • 71 citations

The Effects of Ultraviolet Radiation and Photoreactivation* *Research sponsored by the U. S. Atomic Energy Commission under contract with the Union Carbide Corporation.

1967 • 65 citations

DIRECT DEMONSTRATION OF THE MONOMERIZATION OF THYMINE‐CONTAINING DIMERS IN U.V.‐IRRADIATED DNA BY YEAST PHOTOREACTIVATING ENZYME AND LIGHT*

1967 • 64 citations

VARIATION IN THE PHOTOCHEMICAL REACTIVITY OF THYMINE IN THE DNA OF B. SUBTILIS SPORES, VEGETATIVE CELLS AND SPORES GERMINATED IN CHLORAMPHENICOL*,†

1966 • 64 citations

PHOTOSENSIBILISIERTE CYCLODIMERISATION VON THYMIN IN LÖSUNG

1967 • 64 citations

Post-irradiation degradation of DNA following exposure of UV-sensitive and resistant bacteria to X-rays

1965 • 63 citations

STUDIES ON MECHANISM OF REPAIR OF ULTRAVIOLET-IRRADIATED VIRAL AND BACTERIAL DNA IN VIVO AND IN VITRO

1965 • 62 citations

Sensitivity to ultraviolet light of single- and double-stranded DNA

1963 • 60 citations

Repair of Damaged DNA in a Eucaryotic Cell: Tetrahymena pyriformis

1967 • 60 citations

Deoxyribonucleic acid replication in bacteria following ultraviolet irradiation

1963 • 57 citations

Mammalian Cytogenetics and Related Problems in Radiobiology

1964 • 56 citations

Formation and Destruction of Pyrimidine Dimers in Polynucleotides by Ultra-violet Irradiation in the Presence of Proflavine

1967 • 54 citations

Photoreactivation in an established vertebrate cell line.

1967 • 53 citations

Repair of DNA studied with a nuclease specific for UV-induced lesions.

1966 • 50 citations

Strahlenchemische veränderungen yon pyrimidin en in vivo und in vitro

1961 • 50 citations

THE EFFECT OF PROFLAVINE ON U.V.‐INDUCED DIMERIZATION OF THYMINE IN DNA

1965 • 49 citations

DIFFERENTIAL DESTRUCTION OF THE TRANSFORMING ACTIVITY OF DAMAGED DEOXYRIBONUCLEIC ACID BY A BACTERIAL ENZYME

1962 • 49 citations

Search for a mechanism for the increased sensitivity of 5-bromouracil-substituted DNA to ultraviolet radiation

1968 • 49 citations

The resistance of Micrococcus radiodurans to ultraviolet radiation II. Action spectra for killing, delay in DNA synthesis, and thymine dimerization

1965 • 48 citations

cis-syn Thymine Homodimer from Ultraviolet Irradiated Calf Thymus DNA

1967 • 47 citations

Dependence on wavelength of photoproduct yields in ultraviolet-irradiated poly U

1966 • 46 citations

PRESENCE OF PHOTOREACTIVATING ENZYME IN BLUE‐GREEN ALGAL CELLS*

1968 • 46 citations

Reorientation of chromosome replication after exposure to ultraviolet light of Escherichia coli

1965 • 45 citations

Recent Progress in Photobiology

1965 • 45 citations

Strahlenchemische Veränderungen von Thymin und Cytosin in der DNS durch UV-Licht

1962 • 45 citations

Breakdown of DNA in X-Irradiated Escherichia coli

1966 • 44 citations

Thymine dimer formation in DNA between 25°C and 100°C

1967 • 44 citations

THE ACTION SPECTRUM OF AN IN VITRO DNA PHOTOREACTIVATION SYSTEM

1963 • 42 citations

Repair of DNA damaged by N-methyl-N′-nitro-N-nitrosoguanidine in Escherichia coli

1967 • 42 citations

Excision of pyrimidine dimers from irradiated deoxyribonucleic acid in vitro

1966 • 42 citations

Ultraviolet Damage to Bacteria and Bacteriophage at Low Temperatures

1965 • 42 citations

The minimum size of the substrate for yeast photoreactivating enzyme

1968 • 41 citations

The cross-linking of DNA by ultraviolet radiation

1967 • 38 citations

DNA repair replication in temperature-sensitive DNA synthesis deficient bacteria

1967 • 38 citations

Dark reactivation of ultraviolet irradiated bacteriophage deoxyribonucleic acid in vitro

1964 • 37 citations

Repair of Premutational Damage

1966 • 37 citations

Book Review: Mammalian Cytogenetics and Related Problems in Radiobiology

1965 • 35 citations

Excision of dimers and hydrates from ultraviolet-irradiated poly U by pancreatic ribonuclease

1966 • 34 citations

UV-induzierte Uracil-Dimerisierung in löslicher Ribonucleinsäure

1964 • 34 citations

THE WAVELENGTH‐DEPENDENT FRACTION OF BIOLOGICAL DAMAGE DUE TO THYMINE DIMERS AND TO OTHER TYPES OF LESION IN ULTRAVIOLET‐IRRADIATED DNA

1963 • 34 citations

PHOTOREACTIVATING ENZYME FROM NEUROSPORA CRASSA*

1967 • 32 citations

Quantitative and qualitative aspects of photoreactivation of premutational ultraviolet damage at the ad-3 loci of Neurospora crassa

1967 • 32 citations

THE PHOTOSENSITIZED SOLUTION DIMERIZATTION OF DIMETHYLURACIL AND DIMETHYLTHYMINE. FOUR PHOTODIMERS OF DIMETHYLURACIL

1967 • 31 citations

The structure of DNA-derived thymine dimer

1966 • 31 citations

Ultraviolet light inactivation of the priming ability of DNA in the RNA polymerase system

1965 • 30 citations

Recent Progress in Photobiology

1966 • 30 citations

A mutant of Micrococcus lysodeikticus defective in a deoxyribonuclease activity specific for ultraviolet-irradiated DNA

1967 • 30 citations

Logarithms to Base 2

1955 • 28 citations

Characteristics of an ultraviolet irradiation sensitive strain of Bacillus, subtilis

1965 • 28 citations

The Nature of Photoactivation in Neurospora crassa

1967 • 28 citations

Photoreactivation in vivo of Pyrimidine Dimers in Paramecium DNA

1967 • 27 citations

CONCERNING THE MECHANISM OF FORMATION OF UV-INDUCED THYMINE PHOTOPRODUCTS IN DNA

1967 • 25 citations

Photochemistry of model oligo- and polynucleotides VI. Photodimerization and its reversal in thymine dinucleotide analogues

1962 • 25 citations

Photoreactivating enzyme in the sea urchin egg

1966 • 25 citations

Fate of Thymine-containing Dimers in the Deoxyribonucleic Acid of Ultraviolet-irradiated Bacillus subtilis

1967 • 24 citations

A deoxyribonuclease activity specific for ultraviolet-irradiated DNA: A chromatographic analysis

1967 • 24 citations

OVERLAPPING ACTION OF HOSTCELL REACTIVATION AND PHOTOREACTIVATION IN BACTERIA

1963 • 23 citations

Ultraviolet Mutagenesis in Bacteriophage T4 II. Photoreversal of Mutational Lesions

1966 • 22 citations

Enzymatic Utilization and Degradation of DNA Treated with Mitomycin C or Ultraviolet Light^*

1965 • 22 citations

Ultraviolet Sensitivity of the Biological Activity of ΦX174 Virus, Single-Stranded DNA, and RF DNA

1967 • 21 citations

THE PROPER USE OF SHORT‐WAVELENGTH REVERSAL AS A CRITERION OF THE IMPORTANCE OF PYRIMIDINE DIMERS IN BIOLOGICAL INACTIVATION*

1965 • 20 citations

Pyrimidine Dimers: Effect of Temperature on Photoinduction

1966 • 20 citations

Contribution of Dimers containing Cytosine to Ultra-violet Inactivation of Transforming DNA

1967 • 20 citations

Stability of DNA in Escherichla coli B/r and BS–1 irradiated with Ultra-violet Light

1966 • 19 citations

Early intracellular events in the replication of T4 phage DNA, IV. Host-mediated single-stranded breaks and repair in ultraviolet-damaged T4 DNA.

1967 • 19 citations

Radiation-Induced Reorientation of Chromosome Replication Sequence: Generality in Escherichia coli; Independence of Prophage or 5-Bromouracil Toxicity

1967 • 17 citations

Enzymatic breakdown of UV-irradiated DNA by the extract from Micrococcuslysodeicticus

1966 • 16 citations

Recovery from Ultraviolet- and Alkylating-Agent-Induced Damage in Bacillus subtilis

1966 • 13 citations

Search for repair of ultraviolet damage in mutants of bacteriophage T4

1964 • 13 citations

Nonphotoreactivating Repair of Ultraviolet Light-Damaged Micrococcus lysodeikticus Cells

1965 • 12 citations

Effects of ultraviolet light on polyuridylic acid assayed in vitro

1966 • 11 citations

THE ENZYMATIC DEGRADATION OF ULTRAVIOLET‐IRRADIATED DEOXYRIBONUCLEIC ACID*

1966 • 10 citations

Influence of Monochromatic Ultra-violet Light on the Transformation Activity ofBacillus Subtilis

1963 • 6 citations

Three Levels of DNA Repair in E. coli

1966 • 6 citations

Glucose requirement for DNA breakdown resulting from treatment of Bacillus subtilis with ultraviolet radiation or methyl methanesulfonate

1967 • 6 citations

Evidence that the dark repair system of coliphage T4 is controlled by the viral genome

1966 • 5 citations

Addendum: concerning the mechanism of formation of UV-induced thymine photoproducts in DNA.

1967 • 4 citations

[Two classes of lethal photoreactions in the DNA of bacteriophage 1-phi-7].

1966 • 1 citations

Einfluß von monochromatischem UV-Licht verschiedener Wellenlänge auf die Matrizenfunktion der DNS im RNS-Polymerase-System

1967 • 1 citations