Repair of Chemical Damage to Human DNA

Defective Repair Replication of DNA in Xeroderma Pigmentosum

1968 • 1,739 citations

THE DISAPPEARANCE OF THYMINE DIMERS FROM DNA: AN ERROR-CORRECTING MECHANISM

1964 • 987 citations

Reconstruction in vivo of Irradiated Escherichia coli Deoxyribonucleic Acid; the Rejoining of Broken Pieces

1966 • 727 citations

ASCORBIC ACID IN AROMATIC HYDROXYLATION

1954 • 679 citations

Nitrosamines as Environmental Carcinogens

1970 • 668 citations

EVIDENCE THAT XERODERMA PIGMENTOSUM CELLS DO NOT PERFORM THE FIRST STEP IN THE REPAIR OF ULTRAVIOLET DAMAGE TO THEIR DNA

1969 • 472 citations

XERODERMA PIGMENTOSUM: A HUMAN DISEASE IN WHICH AN INITIAL STAGE OF DNA REPAIR IS DEFECTIVE

1969 • 417 citations

The Metabolic Activation of Carcinogenic Aromatic Amines and Amides1

2015 • 349 citations

Evidence for Excision of Ultraviolet-Induced Pyrimidine Dimers from the DNA of Human Cells In Vitro

1968 • 304 citations

RADIATION-STIMULATED DNA SYNTHESIS IN CULTURED MAMMALIAN CELLS

1966 • 289 citations

Evidence for Repair of Ultra-Violet Damaged Deoxyribonucleic Acid in Cultured Mammalian Cells

1964 • 277 citations

Dimethylnitrosamine: formation of mutagenic compounds by interaction with mouse liver microsomes☆

1971 • 267 citations

Normal and Defective Repair of Damaged DNA in Human Cells: A Sensitive Assay Utilizing the Photolysis of Bromodeoxyuridine

1971 • 212 citations

Mechanism of the Cytotoxic Action of Alkylating Agents in Mammalian Cells and Evidence for the Removal of Alkylated Groups from Deoxyribonucleic Acid

1966 • 184 citations

Quantitative aspects of the repair of alkylated DNA in cultured mammalian cells

1971 • 143 citations

Repair replication in mammalian cells after X-irradiation

1972 • 138 citations

[13] The excision of pyrimidine dimers (The detection of dimers in small amounts)

1971 • 134 citations

Antitumor and mutagenic properties of a variety of heterocyclic nitrogen and sulfur mustards

1972 • 133 citations

DNA repair and chromatid anomalies in mammalian cells exposed to 4-nitroquinoline 1-oxide

1970 • 121 citations

Unscheduled Incorporation of Thymidine in Ultraviolet-Irradiated Human Lymphocytes

1968 • 113 citations

DNA Repair Synthesis in Mammalian Cells exposed to a Series of Oncogenic and Non-Oncogenic Derivatives of 4-Nitroquinoline 1-Oxide

1971 • 105 citations

In vitro Transformation of Syrian Hamster Embryo Cells by Diverse Chemical Carcinogens

1972 • 103 citations

Defective repair of N-acetoxy-2-acetylaminofluorene-induced lesions in the DNA of xeroderma pigmentosum cells

1972 • 91 citations

Xeroderma Pigmentosum: A Rapid Sensitive Method for Prenatal Diagnosis

1971 • 79 citations

Reduced DNA repair synthesis in xeroderma pigmentosum cells exposed to the oncogenic 4-nitroquinoline 1-oxide and 4-hydroxy-aminoquinoline 1-oxide

1971 • 79 citations

Replication of the Bacterial Chromosome: Location of New Initiation Sites After Irradiation

1969 • 75 citations

Mechanism of the sensitization of bacterial transforming DNA to ultraviolet light by the incorporation of 5-bromouracil

1970 • 70 citations

Evidence for repair replication of HeLa cell DNA damaged by ultraviolet light

1968 • 70 citations

Amino Acid Composition of Proteins as a Product of Molecular Evolution

1971 • 56 citations

The action spectra for ultraviolet-light inactivation of systems containing 5-bromouracil-substituted deoxyribonucleic acid

1963 • 50 citations

The action spectra for ultraviolet-light inactivation of systems containing 5-bromouracil-substituted deoxyribonucleic acid☆I. Escherichia coli 15 T−A−U−

1963 • 46 citations

Direct alkylating agents as carcinogens

1968 • 45 citations

Search for a mechanism for the increased sensitivity of 5-bromouracil-substituted DNA to ultraviolet radiation

1970 • 44 citations

Studies on the cellular and molecular mechanisms of hydrocarbon carcinogenesis

1970 • 36 citations

Mutagenic Action, Loss of Transforming Activity, and Inhibition of Deoxyribonucleic Acid Template Activity In Vitro Caused by Chemical Linkage of Carcinogenic Polycyclic Hydrocarbons to Deoxyribonucleic Acid

1971 • 25 citations

UV-induzierte Brüche in 5-Bromuracil-substituierter DNS des Phagen T1 / UV-Induced Strand Breaks in 5-Bromouracil Substituted DNA of Phage T1

1970 • 10 citations