M Cells in Antigen Sampling in Mucosal Tissues

Physiology of the Gastrointestinal Tract

2006 • 4,704 citations

Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity

1991 • 2,806 citations

Common themes in microbial pathogenicity revisited

1997 • 1,370 citations

A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion.

1995 • 1,205 citations

An Electron Microscopic Study

1987 • 1,144 citations

Cellular receptor for poliovirus: Molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulin superfamily

1989 • 1,086 citations

Origins of Cell Polarity

1996 • 1,024 citations

Salmonella typhimurium initiates murine infection by penetrating and destroying the specialized epithelial M cells of the Peyer's patches.

1994 • 859 citations

Common themes in microbial pathogenicity revisited.

1997 • 782 citations

Sequential Uptake of Horseradish Peroxidase by Lymphoid Follicle Epithelium of Peyer's Patches in the Normal Unobstructed Mouse Intestine: An Ultrastructural Study

1977 • 673 citations

INFECTIONS OF THE GASTRO-INTESTINAL TRACT

1980 • 631 citations

Conversion by Peyer's Patch Lymphocytes of Human Enterocytes into M Cells that Transport Bacteria

1997 • 625 citations

Pinocytosis by epithelium associated with lymphoid follicles in the bursa of fabricius, appendix, and Peyer's patches. An electron microscopic study

1973 • 562 citations

Critical role for β7 integrins in formation of the gut-associated lymphoid tissue

1996 • 558 citations

Crystal structure of a cholera toxin-related heat-labile enterotoxin from E. coli

1991 • 556 citations

Epithelial M Cells: Gateways for Mucosal Infection and Immunization

1996 • 536 citations

Organization, Chemistry, and Assembly of the Cytoskeletal Apparatus of the Intestinal Brush Border

1985 • 525 citations

Infections of the Gastrointestinal Tract

1996 • 506 citations

Intestinal M Cells: A Pathway for Entry of Reovirus into the Host

1981 • 481 citations

ANTIGEN SAMPLING ACROSS EPITHELIAL BARRIERS AND INDUCTION OF MUCOSAL IMMUNE RESPONSES

1996 • 462 citations

Mechamisms of cell polarity: sorting and transport in epithelial cells

1994 • 430 citations

Pilus and nonpilus bacterial adhesins: Assembly and function in cell recognition

1993 • 421 citations

Anchoring and Biosynthesis of Stalked Brush Border Membrane Proteins: Glycosidases and Peptidases of Enterocytes and Renal Tubuli

1986 • 405 citations

Role of the glycocalyx in regulating access of microparticles to apical plasma membranes of intestinal epithelial cells: implications for microbial attachment and oral vaccine targeting.

1996 • 392 citations

SALMONELLOSIS: Host Immune Responses and Bacterial Virulence Determinants¹

1996 • 385 citations

Receptor-mediated transcytosis of IgA in MDCK cells is via apical recycling endosomes.

1994 • 384 citations

Signal transduction in the mammalian cell during bacterial attachment and entry

1993 • 364 citations

M Cell Transport of Vibrio cholerae from the Intestinal. Lumen into Peyer's Patches: A Mechanism for Antigen Sampling and for Microbial Transepithelial Migration

1986 • 349 citations

Signal transduction between enteropathogenic Escherichia coli (EPEC) and epithelial cells: EPEC induces tyrosine phosphorylation of host cell proteins to initiate cytoskeletal rearrangement and bacterial uptake.

1992 • 328 citations

Involvement of M cells in the bacterial invasion of Peyer's patches: a common mechanism shared by Yersinia enterocolitica and other enteroinvasive bacteria.

1990 • 276 citations

Structure, Distribution, and Origin of M Cells in Peyer’s Patches of Mouse Ileum

1984 • 275 citations

Role of M cells in initial antigen uptake and in ulcer formation in the rabbit intestinal loop model of shigellosis

1989 • 272 citations

New model for analysis of mucosal immunity: intestinal secretion of specific monoclonal immunoglobulin A from hybridoma tumors protects against Vibrio cholerae infection

1991 • 257 citations

Differentiation and self-renewal in the mouse gastrointestinal epithelium

1994 • 256 citations

Transport of membrane-bound macromolecules by M cells in follicle-associated epithelium of rabbit Peyer's patch

1987 • 253 citations

Infection of colonic epithelial cell lines by type 1 human immunodeficiency virus is associated with cell surface expression of galactosylceramide, a potential alternative gp120 receptor.

1993 • 242 citations

Binding and transepithelial transport of immunoglobulins by intestinal M cells: demonstration using monoclonal IgA antibodies against enteric viral proteins.

1989 • 235 citations

Uptake and translocation of fluorescent latex particles by rabbit Peyer's patch follicle epithelium: a quantitative model for M cell uptake.

1989 • 222 citations

Cytopathogenic Effect of Salmonella typhi GIFU 10007 on M cells of Murine Ileal Peyer's Patches in Ligated Ileal Loops: An Ultrastructural Study

1986 • 219 citations

Differential expression of lectin-binding sites defines mouse intestinal M-cells.

1993 • 219 citations

Poliovirus type 1 enters the human host through intestinal M cells

1990 • 215 citations

Specific adherence of Escherichia coli (strain RDEC-1) to membranous (M) cells of the Peyer's patch in Escherichia coli diarrhea in the rabbit.

1983 • 206 citations

Transepithelial transport of HIV-1 by intestinal M cells: a mechanism for transmission of AIDS.

1991 • 204 citations

Cell migration pathway in the intestinal epithelium: An in situ marker system using mouse aggregation chimeras

1985 • 187 citations

Cytochemical analysis of alkaline phosphatase and esterase activities and of lectin‐binding and anionic sites in rat and mouse Peyer's patch M cells

1983 • 174 citations

M cells and the pathogenesis of mucosal and systemic infections

1996 • 168 citations

Advances in Mucosal Immunology

1995 • 165 citations

Regional differences in glycoconjugates of intestinal M cells in mice: potential targets for mucosal vaccines

1994 • 153 citations

Lectins are sensitive tools for defining the differentiation programs of mouse gut epithelial cell lineages

1994 • 153 citations

Salmonella-induced M-cell formation in germ-free mouse Peyer's patch tissue.

1991 • 151 citations

Regulation of protein traffic in polarized epithelial cells.

1995 • 138 citations

Form and function of the glycocalyx on free cell surfaces

1974 • 129 citations

Heterogeneity of M-cell-associated B and T cells in human Peyer's patches.

1994 • 121 citations

Rat intestinal M cells contain acidic endosomal-lysosomal compartments and express class II major histocompatibility complex determinants

1993 • 115 citations

Actin isoform synthesis and mRNA levels in quiescent and proliferating rat aortic smooth muscle cells in vivo and in vitro.

1986 • 115 citations

Cathepsin E in follicle associated epithelium of intestine and tonsils: localization to M cells and possible role in antigen processing

1993 • 112 citations

Absence of secretory component expression by epithelial cells overlying rabbit gut-associated lymphoid tissue

1988 • 111 citations

Intestinal epithelial cells as watchdogs for the natural immune system

1995 • 111 citations

Uptake and transport of copolymer biodegradable microspheres by rabbit Peyer's patch M cells

1995 • 110 citations

Proteolytic processing of reovirus is required for adherence to intestinal M cells

1994 • 110 citations

Selective association and transport of Campylobacter jejuni through M cells of rabbit Peyer's patches

1988 • 104 citations

Mechanisms of viral pathogenesis. Distinct forms of reoviruses and their roles during replication in cells and host.

1991 • 98 citations

M cell numbers increase after transfer of SPF mice to a normal animal house environment.

1987 • 94 citations

Differential distribution of lymphocytes and accessory cells in mouse Peyer's patches

1986 • 94 citations

Mucosal IgA response to rectally administered antigen formulated in IgA-coated liposomes

1995 • 87 citations

Characterization of the receptor for cholera toxin and Escherichia coli heat-labile toxin in rabbit intestinal brush borders

1986 • 82 citations

Differential binding of lectins to M cells and enterocytes in the rabbit cecum

1993 • 79 citations

Development of dome epithelium in gut-associated lymphoid tissues: Association of IgA with M cells

1987 • 79 citations

Co-localization of vimentin and cytokeratins in M-cells of rabbit gut-associated lymphoid tissue (GALT)

1992 • 77 citations

The Filamentous Brush Border Glycocalyx, a Mucin-like Marker of Enterocyte Hyper-Polarization

1995 • 76 citations

Electrokinetic and electrostatic properties of bilayers containing gangliosides GM1, GD1a, or GT1. Comparison with a nonlinear theory

1986 • 71 citations

Structure and function of the intestinal epithelial barrier in health and disease.

1990 • 70 citations

Immune cells associated with M cells in the follicle-associated epithelium of Peyer's patches in the rat

1989 • 65 citations

Reovirus type I infection of small intestinal epithelium in suckling mice and its effect on M cells.

1988 • 64 citations

Ultrastructural study of liposome uptake by M cells of rat Peyer's patch: an oral vaccine system for delivery of purified antigen.

1990 • 63 citations

MODIFICATIONS OF THE FOLLICLE-ASSOCIATED EPITHELIUM BY SHORT-TERM EXPOSURE TO A NON-INTESTINAL BACTERIUM

1996 • 60 citations

Cytosolic distribution of villin in M cells from mouse Peyer's patches correlates with the absence of a brush border

1996 • 59 citations

The Heat-Labile Enterotoxin of Escherichia coli Binds to Polylactosaminoglycan-Containing Receptors in CaCo-2 Human Intestinal Epithelial Cells

1994 • 58 citations

The Filamentous Brush Border Glycocalyx, a Mucin-like Marker of Enterocyte Hyper-Polarization

1995 • 55 citations

A Pathogen-specific Epitope Inserted into Recombinant Secretory Immunoglobulin A Is Immunogenic by the Oral Route

1996 • 55 citations

A pathway for entry of reoviruses into the host through M cells of the respiratory tract.

1994 • 53 citations

Phenotypically distinct subpopulations of T cells in domes and M-cell pockets of rabbit gut-associated lymphoid tissues.

1990 • 53 citations

Epithelial M cells in the rabbit caecal lymphoid patch display distinctive surface characteristics

1993 • 50 citations

Mechanisms of Viral Pathogenesis

1984 • 36 citations

Evidence that Membranous (M) Cell Genesis is Immuno-Regulated

1995 • 34 citations

Linear arrays of intramembrane particles on microvilli in primate large intestine

1979 • 32 citations

Lymphocyte compartments in antigen-sampling regions of rabbit mucosal lymphoid organs.

1994 • 31 citations

M cells are damaged and increased in number in inflamed human ileal mucosa.

1993 • 29 citations

Unique Features of Antigen Presentation in the Intestinea

1992 • 27 citations

Role of heterotrimeric G proteins in polarized membrane transport

1993 • 26 citations

Migration of neutrophils through epithelial monolayers

1994 • 24 citations

Membrane Domains and Macromolecular Transport in Intestinal Epithelial Cells

1988 • 19 citations

Phenotype and distribution of T lymphocytes in Peyer's patches of athymic mice

1987 • 15 citations

Ultrastructural radioautography of synthesis and migration of proteins and catecholamines in the rat adrenal medulla

1982 • 14 citations

Antigen Uptake by M Cells for Effective Mucosal Vaccines

1996 • 14 citations