Eight genes and alternative RNA processing pathways generate an unexpectedly large diversity of cytoplasmic intermediate filament proteins in the nematode Caenorhabditis elegans.

Molecular cloning: A laboratory manual

1990 • 85,659 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

3′ Non-coding region sequences in eukaryotic messenger RNA

1976 • 3,001 citations

The Nematode Caenorhabditis elegans

1988 • 2,868 citations

An analysis of vertebrate mRNA sequences: intimations of translational control.

1991 • 1,655 citations

Transcription termination and 3′ processing: the end is in site!

1985 • 1,482 citations

INTERMEDIATE FILAMENTS: Structure, Dynamics, Function and Disease

1994 • 1,408 citations

MOLECULAR AND CELLULAR BIOLOGY OF INTERMEDIATE FILAMENTS

1988 • 1,395 citations

Magnesium precipitation of ribonucleoprotein complexes. Expedient techniques for the isolation of undegraded polysomes and messenger ribonucleic acid

1974 • 987 citations

Homologies in both primary and secondary structure between nuclear envelope and intermediate filament proteins

1986 • 836 citations

cDNA sequencing of nuclear lamins A and C reveals primary and secondary structural homology to intermediate filament proteins.

1986 • 711 citations

All classes of intermediate filaments share a common antigenic determinant defined by a monoclonal antibody

1981 • 654 citations

The pharynx of Caenorhabditis elegans

1976 • 649 citations

Point mutations in human keratin 14 genes of epidermolysis bullosa simplex patients: Genetic and functional analyses

1991 • 647 citations

A trans-spliced leader sequence on actin mRNA in C. elegans

1987 • 639 citations

Toward a physical map of the genome of the nematode Caenorhabditis elegans

1986 • 631 citations

The C. elegans genome sequencing project: a beginning

1992 • 496 citations

A mutation in the conserved helix termination peptide of keratin 5 in hereditary skin blistering

1992 • 406 citations

UNC-5, a transmembrane protein with immunoglobulin and thrombospondin type 1 domains, guides cell and pioneer axon migrations in C. elegans

1992 • 404 citations

Trans splicing of nuclear pre-mRNAs

1990 • 383 citations

Muscle cell attachment in Caenorhabditis elegans.

1991 • 371 citations

Mutations in the Rod Domains of Keratins 1 and 10 in Epidermolytic Hyperkeratosis

1992 • 370 citations

A survey of expressed genes in Caenorhabditis elegans

1992 • 355 citations

Operons in C. elegans: Polycistronic mRNA precursors are processed by trans-splicing of SL2 to downstream coding regions

1993 • 293 citations

Evidence that introns arose at proto-splice sites.

1989 • 235 citations

The structure and organization of the human heavy neurofilament subunit (NF-H) and the gene encoding it.

1988 • 234 citations

The structure of the vimentin gene

1983 • 227 citations

Characterization of the human nestin gene reveals a close evolutionary relationship to neurofilaments

1992 • 214 citations

Vinculin is essential for muscle function in the nematode.

1991 • 173 citations

Remarkable conservation of structure among intermediate filament genes

1984 • 169 citations

Amino acid sequence and gene organization of cytokeratin no. 19, an exceptional tail-less intermediate filament protein.

1986 • 167 citations

Structure of a gene for the human epidermal 67-kDa keratin.

1985 • 160 citations

A second trans-spliced RNA leader sequence in the nematode Caenorhabditis elegans.

1989 • 149 citations

Cis and trans mRNA splicing in C. elegans

1988 • 144 citations

A new selective phage cloning vector, λ2001, with sites for XbaI, BamHI, HindIII, EcoRI, SstI and XhoI

1984 • 144 citations

Presence of the Caenorhabditis elegans spliced leader on different mRNAs and in different genera of nematodes.

1988 • 142 citations

Cytoplasmic intermediate filament proteins of invertebrates are closer to nuclear lamins than are vertebrate intermediate filament proteins; sequence characterization of two muscle proteins of a nematode.

1989 • 134 citations

The sequence of a type II keratin gene expressed in human skin: conservation of structure among all intermediate filament genes.

1985 • 128 citations

Structure of an invertebrate gene encoding cytoplasmic intermediate filament (IF) proteins: implications for the origin and the diversification of IF proteins.

1990 • 127 citations

OBLIQUELY STRIATED MUSCLE

1967 • 120 citations

YACs and the C. elegans genome

1991 • 118 citations

Gene structure of nuclear lamin LIII of Xenopus laevis; a model for the evolution of IF proteins from a lamin-like ancestor.

1990 • 117 citations

Organization of a type I keratin gene. Evidence for evolution of intermediate filaments from a common ancestral gene.

1985 • 91 citations

Bovine filensin possesses primary and secondary structure similarity to intermediate filament proteins.

1993 • 90 citations

Information content ofCaenorhabditis eleganssplice site sequences varies with intron length

1990 • 85 citations

Genomic organization of major sperm protein genes and pseudogenes in the nematode Caenorhabditis elegans

1988 • 78 citations

A nuclear lamin of the nematode Caenorhabditis elegans with unusual structural features; cDNA cloning and gene organization.

1993 • 69 citations

A high-molecular-weight squid neurofilament protein contains a lamin-like rod domain and a tail domain with Lys-Ser-Pro repeats.

1992 • 66 citations

Amino acid sequences and homopolymer-forming ability of the intermediate filament proteins from an invertebrate epithelium.

1988 • 60 citations

Squid low molecular weight neurofilament proteins are a novel class of neurofilament protein. A nuclear lamin-like core and multiple distinct proteins formed by alternative RNA processing

1991 • 59 citations

Intermediate filaments in muscle and epithelial cells of nematodes.

1986 • 58 citations

Intermediate filaments in non-neuronal cells of invertebrates: isolation and biochemical characterization of intermediate filaments from the esophageal epithelium of the mollusc Helix pomatia.

1985 • 58 citations

Chicken filensin: a lens fiber cell protein that exhibits sequence similarity to intermediate filament proteins

1993 • 57 citations

Organization and sequence of the human gene encoding cytokeratin 8

1990 • 55 citations

Gene structure and chromosomal localization of the murine lamin B2 gene.

1991 • 39 citations

Analysis of the cDNA and gene encoding a cytoplasmic intermediate filament (IF) protein from the cephalochordate Branchiostoma lanceolatum; implications for the evolution of the IF protein family.

1992 • 36 citations

Cloning of the non-neuronal intermediate filament protein of the gastropod Aplysia californica; identification of an amino acid residue essential for the IFA epitope.

1991 • 35 citations

Primary structure and lens-specific expression of genes for an intermediate filament protein and a β-tubulin in cephalopods

1993 • 34 citations

Molecular analysis of the Drosophila nuclear lamin gene

1990 • 34 citations

Intermediate filaments in the giant muscle cells of the nematode Ascaris lumbricoides; abundance and three-dimensional complexity of arrangements.

1988 • 16 citations