Chemically induced hypothyroidism produces elevated amounts of the α subunit of the inhibitory guanine nucleotide binding protein (Gi) and the β subunit common to all G-proteins

Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain.

1984 • 1,300 citations

Purification and properties of the inhibitory guanine nucleotide regulatory unit of brain adenylate cyclase.

1984 • 585 citations

Signal transduction by guanine nucleotide binding proteins

1987 • 362 citations

Abolition of the expression of inhibitory guanine nucleotide regulatory protein Gi activity in diabetes

1987 • 232 citations

The properties and extracellular location of 5′-nucleotidase of the rat fat-cell plasma membrane

1975 • 170 citations

Use of specific antibodies to quantitate the guanine nucleotide-binding protein Go in brain.

1986 • 158 citations

Primary structure of the α‐subunit of bovine adenylate cyclase‐stimulating G‐protein deduced from the cDNA sequence

1986 • 142 citations

The inhibitory guanine nucleotide-binding protein (Ni) purified from bovine brain is a high affinity GTPase.

1985 • 140 citations

The insulin receptor tyrosyl kinase phosphorylates holomeric forms of the guanine nucleotide regulatory proteins G_i and G_o

1987 • 126 citations

Antibodies against the carboxyl-terminal 5-kDa peptide of the alpha subunit of transducin crossreact with the 40-kDa but not the 39-kDa guanine nucleotide binding protein from brain.

1985 • 98 citations

The GTP‐binding regulatory proteins of neuroblastoma × glioma, NG108‐15, and glioma, C6, cells

1986 • 87 citations

Human G_i protein α‐subunit: deduction of amino acid structure from a cloned cDNA

1987 • 85 citations

The fractionation of nuclei from mammalian cells by zonal centrifugation

1968 • 81 citations

Fat cell adenylate cyclase system. Enhanced inhibition by adenosine and GTP in the hypothyroid rat.

1985 • 80 citations

Detection of the major pertussis toxin substrate of human leukocytes with antisera raised against synthetic peptides

1986 • 55 citations

Changes in the guanine nucleotide‐binding proteins, G_i and g_o, during differentiation of 3T3‐L1 cells

1986 • 51 citations

Changes in the anti-lipolytic action and binding to plasma membranes of N6-L-phenylisopropyladenosine in adipocytes from starved and hypothyroid rats

1984 • 46 citations

Sensitivity of adipocyte lipolysis to stimulatory and inhibitory agonists in hypothyroidism and starvation

1986 • 40 citations

Pertussis toxin effects on adenylate cyclase activity, cyclic AMP accumulation and lipolysis in adipocytes from hypothyroid, euthyroid and hyperthyroid rats

1986 • 34 citations

Enzymes involved in adenosine metabolism in rat white and brown adipocytes. Effects of streptozotocin-diabetes, hypothyroidism, age and sex differences

1987 • 30 citations

The stimulatory guanine-nucleotide regulatory unit of adenylate cyclase from bovine cerebral cortex ADP-ribosylation and purification

1987 • 29 citations

The use of specific antibodies to identify and quantify guanine nucleotide-binding proteins

1987 • 18 citations