Pertussis toxin effects on adenylate cyclase activity, cyclic AMP accumulation and lipolysis in adipocytes from hypothyroid, euthyroid and hyperthyroid rats

Metabolism of Isolated Fat Cells

1964 • 4,431 citations

Loss of the inhibitory function of the guanine nucleotide regulatory component of adenylate cyclase due to its ADP ribosylation by islet-activating protein, pertussis toxin, in adipocyte membranes.

1983 • 406 citations

Regulation of adenylate cyclase by adenosine

1979 • 218 citations

Fat cell adenylate cyclase and beta-adrenergic receptors in altered thyroid states.

1978 • 216 citations

The fat cell adenylate cyclase system. Characterization and manipulation of its bimodal regulation by GTP.

1979 • 171 citations

Forskolin as an activator of cyclic AMP accumulation and lipolysis in rat adipocytes.

1982 • 141 citations

Effects of pertussis toxin treatment on the metabolism of rat adipocytes.

1983 • 112 citations

Cyclic nucleotide phosphodiesterases and thyroid hormones.

1975 • 110 citations

Fat cell adenylate cyclase system. Enhanced inhibition by adenosine and GTP in the hypothyroid rat.

1985 • 80 citations

Thyroid-catecholamine interactions in isolated rat brown adipocytes

1984 • 58 citations

Adenosine, thyroid status and regulation of lipolysis

1979 • 58 citations

Decreased sensitivity to α₂ adrenergic amines, adenosine and prostaglandins in white fat cells from hamsters treated with pertussis vaccine

1981 • 52 citations

ADP-ribosylation of membrane proteins and activation of adenylate cyclase by cholera toxin in fat cell ghosts from euthyroid and hypothyroid rats

1979 • 48 citations

Changes in the anti-lipolytic action and binding to plasma membranes of N6-L-phenylisopropyladenosine in adipocytes from starved and hypothyroid rats

1984 • 46 citations

Fat cell beta-adrenergic receptor in the hypothyroid rat. Impaired interaction with the stimulatory regulatory component of adenylate cyclase.

1984 • 42 citations

Catecholamine-thyroid hormone interactions in liver and adipose tissue

1981 • 37 citations

Cyclic nucleotide phosphodiesterases, insulin and thyroid hormones

1976 • 32 citations

Effect of pertussis toxin on the hormonal regulation of cyclic AMP levels in hamster fat cells

1983 • 30 citations

Triiodothyronine Stimulation of Cyclic Adenosine 3’, 5’-Monophosphate Accumulation in Fat Cells*

1971 • 29 citations

Calorigenic Action of Triiodothyronine on White Fat Cells: Effects of Ouabain, Oligomycin, and Catecholamines

1971 • 25 citations

The effects of thyroid status on the modulation of fat cell beta-adrenergic receptor agonist affinity by guanine nucleotides.

1980 • 25 citations

Effect of thyroid status on α- and β-catecholamine responsiveness of hamster adipocytes

1981 • 19 citations

Adenosine deaminase normalizes cyclic AMP responses of hypothyroid rat fat cells to forskolin, but not β-adrenergic agonists

1983 • 16 citations

Thyroid hormones and fat cell phosphorylation

1984 • 3 citations