Modulation of hippocampal synaptic transmission and plasticity by neurotrophins

Neurotrophins and Neuronal Plasticity

1995 • 1,937 citations

Physiology of the Neurotrophins

1996 • 1,908 citations

Ca2+ Influx Regulates BDNF Transcription by a CREB Family Transcription Factor-Dependent Mechanism

1998 • 1,504 citations

Short-Term Synaptic Plasticity

1989 • 1,464 citations

Hippocampal long-term potentiation is impaired in mice lacking brain-derived neurotrophic factor.

1995 • 1,416 citations

Long-lasting neurotrophin-induced enhancement of synaptic transmission in the adult hippocampus

1995 • 1,354 citations

NEUROTROPHINS AND SYNAPTIC PLASTICITY

1999 • 1,343 citations

NT-3, BDNF, and NGF in the developing rat nervous system: Parallel as well as reciprocal patterns of expression

1990 • 1,238 citations

Recombinant BDNF Rescues Deficits in Basal Synaptic Transmission and Hippocampal LTP in BDNF Knockout Mice

1996 • 1,219 citations

Heterogeneity of Release Probability, Facilitation, and Depletion at Central Synapses

1997 • 1,209 citations

BDNF Regulates the Maturation of Inhibition and the Critical Period of Plasticity in Mouse Visual Cortex

1999 • 1,180 citations

Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus

1996 • 1,104 citations

Mice lacking brain-derived neurotrophic factor develop with sensory deficits

1994 • 1,066 citations

Quantitative Ultrastructural Analysis of Hippocampal Excitatory Synapses

1997 • 973 citations

Neurotrophins regulate dendritic growth in developing visual cortex

1995 • 963 citations

Intracellular Signaling Pathways Activated by Neuropathic Factors

1996 • 958 citations

A Requirement for Local Protein Synthesis in Neurotrophin-Induced Hippocampal Synaptic Plasticity

1996 • 948 citations

Requirement of a Critical Period of Transcription for Induction of a Late Phase of LTP

1994 • 889 citations

Anisomycin, an inhibitor of protein synthesis, blocks late phases of LTP phenomena in the hippocampal CA1 region in vitro

1988 • 800 citations

Essential Role for TrkB Receptors in Hippocampus-Mediated Learning

1999 • 797 citations

Potentiation of developing neuromuscular synapses by the neurotrophins NT-3 and BDNF

1993 • 753 citations

Neurotrophin receptors: A window into neuronal differentiation

1992 • 704 citations

Identification of a Signaling Pathway Involved in Calcium Regulation of BDNF Expression

1998 • 687 citations

Brain-derived neurotrophic factor rapidly enhances synaptic transmission in hippocampal neurons via postsynaptic tyrosine kinase receptors.

1995 • 612 citations

Effects of brain-derived neurotrophic factor on optic axon branching and remodelling in vivo

1995 • 583 citations

Opposing Roles for Endogenous BDNF and NT-3 in Regulating Cortical Dendritic Growth

1997 • 578 citations

Inhibition of Ocular Dominance Column Formation by Infusion of NT-4/5 or BDNF

1995 • 572 citations

Neurotrophin expression in rat hippocampal slices: A stimulus paradigm inducing LTP in CA1 evokes increases in BDNF and NT-3 mRNAs

1992 • 564 citations

Neurotrophin signal transduction by the Trk receptor

1994 • 511 citations

Neurotrophin Regulation of Cortical Dendritic Growth Requires Activity

1996 • 503 citations

Neurotrophins and Time: Different Roles for TrkB Signaling in Hippocampal Long-Term Potentiation

1997 • 482 citations

Learning Deficit in BDNF Mutant Mice

1997 • 470 citations

Impairments in High-Frequency Transmission, Synaptic Vesicle Docking, and Synaptic Protein Distribution in the Hippocampus of BDNF Knockout Mice

1999 • 463 citations

BDNF Has Opposite Effects on the Quantal Amplitude of Pyramidal Neuron and Interneuron Excitatory Synapses

1998 • 460 citations

Changes in paired-pulse facilitation suggest presynaptic involvement in long-term potentiation

1994 • 430 citations

Brain-derived neurotrophic factor modulates hippocampal synaptic transmission by increasing N -methyl- <scp>d</scp> -aspartic acid receptor activity

1998 • 406 citations

BDNF, and NT-4/5 enhance glutamatergic synaptic transmission in cultured hippocampal neurones

1994 • 402 citations

The Role of Brain-Derived Neurotrophic Factor Receptors in the Mature Hippocampus: Modulation of Long-Term Potentiation through a Presynaptic Mechanism involving TrkB

2000 • 399 citations

Inhibition of GABA_ASynaptic Responses by Brain-Derived Neurotrophic Factor (BDNF) in Rat Hippocampus

1997 • 387 citations

Virus-mediated gene transfer into hippocampal CA1 region restores long-term potentiation in brain-derived neurotrophic factor mutant mice.

1996 • 350 citations

Enhancement of Neurotransmitter Release Induced by Brain-Derived Neurotrophic Factor in Cultured Hippocampal Neurons

1998 • 317 citations

The induction of LTP increases BDNF and NGF mRNA but decreases NT-3 mRNA in the dentate gyrus

1993 • 313 citations

Blockade of Endogenous Ligands of TrkB Inhibits Formation of Ocular Dominance Columns

1997 • 309 citations

Brain-derived neurotrophic factor transgenic mice exhibit passive avoidance deficits, increased seizure severity and in vitro hyperexcitability in the hippocampus and entorhinal cortex

1999 • 306 citations

Neurotrophins and activity-dependent development of the neocortex

1996 • 305 citations

Positive Feedback between Acetylcholine and the Neurotrophins Nerve Growth Factor and Brain‐derived Neurotrophic Factor in the Rat Hippocampus

1994 • 301 citations

Presynaptic Modulation of Synaptic Transmission and Plasticity by Brain-Derived Neurotrophic Factor in the Developing Hippocampus

1998 • 284 citations

Brain-Derived Neurotrophic Factor Enhances Long-Term Potentiation in Rat Visual Cortex

1997 • 283 citations

Deprivation of endogenous brain-derived neurotrophic factor results in impairment of spatial learning and memory in adult rats

1999 • 281 citations

BDNF acutely increases tyrosine phosphorylation of the NMDA receptor subunit 2B in cortical and hippocampal postsynaptic densities

1998 • 278 citations

TrkB and TrkC Signaling Are Required for Maturation and Synaptogenesis of Hippocampal Connections

1998 • 266 citations

A role for BDNF in the late-phase of hippocampal long-term potentiation

1998 • 260 citations

Neurotrophic factors and synaptic plasticity

1995 • 259 citations

Nerve growth factor (NGF) prevents the shift in ocular dominance distribution of visual cortical neurons in monocularly deprived rats

1992 • 255 citations

Neurotrophins promote maturation of developing neuromuscular synapses

1995 • 249 citations

Brain-Derived Neurotrophic Factor Differentially Regulates Retinal Ganglion Cell Dendritic and Axonal ArborizationIn Vivo

1999 • 245 citations

Relative Contribution of Endogenous Neurotrophins in Hippocampal Long-Term Potentiation

1999 • 242 citations

Role of Neurotrophins in Synapse Development and Plasticity

1997 • 241 citations

Learning upregulates brain-derived neurotrophic factor messenger ribonucleic acid: A mechanism to facilitate encoding and circuit maintenance?

1998 • 228 citations

Brain-derived neurotrophic factor antisense oligonucleotide impairs memory retention and inhibits long-term potentiation in rats

1997 • 226 citations

Synaptic Modulation by Neurotrophic Factors: Differential and Synergistic Effects of Brain-Derived Neurotrophic Factor and Ciliary Neurotrophic Factor

1996 • 224 citations

Long‐term enhancement of CA1 synaptic transmission is due to increased quantal size, not quantal content

1991 • 218 citations

Nerve growth factor: a tale of two receptors.

1993 • 215 citations

Cells that Express Brain‐Derived Neurotrophic Factor mRNA in the Developing Postnatal Rat Brain

1991 • 208 citations

Acute Intrahippocampal Infusion of BDNF Induces Lasting Potentiation of Synaptic Transmission in the Rat Dentate Gyrus

1998 • 207 citations

Learning upregulates brain-derived neurotrophic factor messenger ribonucleic acid: A mechanism to facilitate encoding and circuit maintenance?

1998 • 205 citations

Brain-Derived Neurotrophic Factor (BDNF) Modulates Inhibitory, But Not Excitatory, Transmission in the CA1 Region of the Hippocampus

1998 • 204 citations

NT-4-mediated rescue of lateral geniculate neurons from effects of monocular deprivation

1995 • 202 citations

Developmental expression of trkC, the neurotrophin-3 receptor, in the mammalian nervous system

1994 • 202 citations

Quantal analysis of excitatory synaptic action and depression in hippocampal slices

1991 • 197 citations

Very short-term plasticity in hippocampal synapses

1997 • 196 citations

The Synaptophysin–Synaptobrevin Complex: a Hallmark of Synaptic Vesicle Maturation

1999 • 179 citations

Fast actions of neurotrophic factors

1996 • 177 citations

Potentiation of Developing Synapses by Postsynaptic Release of Neurotrophin-4

1997 • 176 citations

Expression of members of the trk family in the developing postnatal rat brain

1993 • 174 citations

Reversal of spatial memory impairments in aged rats by nerve growth factor and neurotrophins 3 and 4/5 but not by brain-derived neurotrophic factor.

1994 • 172 citations

Hyperexcitability in Combined Entorhinal/Hippocampal Slices of Adult Rat After Exposure to Brain-Derived Neurotrophic Factor

1997 • 165 citations

Modulation of unitary glutamatergic synapses by neurotrophin-4/5 or brain-derived neurotrophic factor in hippocampal microcultures: presynaptic enhancement depends on pre-established paired-pulse facilitation

1998 • 165 citations

Signaling Mechanisms Mediating BDNF Modulation of Synaptic Plasticity in the Hippocampus

1999 • 162 citations

Brain-derived neurotrophic factor expression after long-term potentiation

1993 • 158 citations

Expression of a dominant negative TrkB receptor, T1, reveals a requirement for presynaptic signaling in BDNF-induced synaptic potentiation in cultured hippocampal neurons

1998 • 157 citations

Brain‐Derived Neurotrophic Factor Increases the Stimulation‐Evoked Release of Glutamate and the Levels of Exocytosis‐Associated Proteins in Cultured Cortical Neurons from Embryonic Rats

1997 • 146 citations

BDNF Modulates, But Does Not Mediate, Activity-Dependent Branching and Remodeling of Optic Axon ArborsIn Vivo

1999 • 143 citations

Neurotrophin–3 is required for proper cerebellar development

1999 • 139 citations

Unilateral LTP triggers bilateral increases in hippocampal neurotrophin andtrk receptor mRNA expression in behaving rats: Evidence for interhemispheric communication

1996 • 137 citations

Potentiation of Transmitter Release by Ciliary Neurotrophic Factor Requires Somatic Signaling

1995 • 128 citations

Neurotrophin Modulation of NMDA Receptors in Cultured Murine and Isolated Rat Neurons

1997 • 120 citations

Functional trkB neurotrophin receptors are intrinsic components of the adult brain postsynaptic density

1996 • 112 citations

Nerve growth factor prevents the amblyopic effects of monocular deprivation.

1991 • 112 citations

Actions of Brain-Derived Neurotrophic Factor in Slices from Rats with Spontaneous Seizures and Mossy Fiber Sprouting in the Dentate Gyrus

1999 • 110 citations

Brain-derived neurotrophic factor alters the synaptic modification threshold in visual cortex

1998 • 109 citations

Intact spatial learning and memory in transgenic mice with reduced BDNF

1997 • 96 citations

Brain-derived neurotrophic factor blocks long-term depression in rat visual cortex

1996 • 96 citations

NMDA receptor subunits in the postsynaptic density of rat brain: expression and phosphorylation by endogenous protein kinases

1998 • 89 citations

Brain-derived Neurotrophic Factor Induces Rapid and Transient Release of Glutamate through the Non-exocytotic Pathway from Cortical Neurons

1998 • 88 citations

Activity-Dependent Expression of NT-3 in Muscle Cells in Culture: Implications in the Development of Neuromuscular Junctions

1997 • 88 citations

Selective role for trkB neurotrophin receptors in rapid modulation of hippocampal synaptic transmission

1996 • 71 citations

Localized Synaptic Actions of Neurotrophin-4

1998 • 71 citations

Determinants of BDNF-induced hippocampal synaptic plasticity: role of the Trk B receptor and the kinetics of neurotrophin delivery.

1996 • 70 citations

Brain-Derived Neurotrophic Factor Prevents Low-Frequency Inputs from Inducing Long-Term Depression in the Developing Visual Cortex

1999 • 68 citations

Endogenous Neurotrophin-3 Regulates Short-Term Plasticity at Lateral Perforant Path–Granule Cell Synapses

1998 • 63 citations

The effects of intrahippocampal BDNF and NGF on spatial learning in aged long evans rats

1996 • 62 citations

Time-Dependent Changes in Neurotrophic Factor mRNA Expression after Kindling and Long-Term Potentiation in Rats

1998 • 61 citations

Synaptic Reliability Correlates with Reduced Susceptibility to Synaptic Potentiation by Brain-Derived Neurotrophic Factor

1999 • 58 citations

Regulation of Quantal Secretion from Developing Motoneurons by Postsynaptic Activity-Dependent Release of NT-3

1997 • 52 citations

Regulation of Quantal Secretion by Neurotrophic Factors at Developing Motoneurons in Xenopus Cell Cultures

1997 • 52 citations

TrkB expression in dentate granule cells is associated with a late phase of long-term potentiation

1997 • 45 citations

Brain-derived neurotrophic factor rapidly potentiates synaptic transmission through NMDA, but suppresses it through non-NMDA receptors in rat hippocampal neuron

1998 • 45 citations

Neuronal NT-3 Is not Required For Synaptic Transmission or Long-Term Potentiation in Area CA1 of the Adult Rat Hippocampus

1999 • 32 citations

Transient elevation in catalytic trkB mRNA during postnatal development of the rat brain.

1993 • 20 citations