Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries

Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women: Principal Results From the Women's Health Initiative Randomized Controlled Trial

2002 • 15,184 citations

2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer

2015 • 14,057 citations

Reduced Lung-Cancer Mortality with Low-Dose Computed Tomographic Screening

2011 • 9,173 citations

Human papillomavirus is a necessary cause of invasive cervical cancer worldwide

1999 • 8,737 citations

Estimating the global cancer incidence and mortality in 2018: GLOBOCAN sources and methods

2018 • 6,648 citations

Cancer Incidence in Five Continents

1966 • 5,960 citations

Global surveillance of trends in cancer survival 2000–14 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries

2018 • 4,919 citations

Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies

2008 • 4,777 citations

Global patterns and trends in colorectal cancer incidence and mortality

2016 • 4,347 citations

Colorectal cancer statistics, 2020

2020 • 4,154 citations

The Epidemiologic Transition: A Theory of the Epidemiology of Population Change

2005 • 3,730 citations

Breast cancer statistics, 2019

2019 • 2,716 citations

The Epidemiologic Transition: A Theory of the Epidemiology of Population Change

1971 • 2,648 citations

Global Prevalence of Helicobacter pylori Infection: Systematic Review and Meta-Analysis

2017 • 2,634 citations

Reduced Lung-Cancer Mortality with Volume CT Screening in a Randomized Trial

2020 • 2,381 citations

Screening for Prostate Cancer: U.S. Preventive Services Task Force Recommendation Statement

2012 • 2,379 citations

Cancer burden in the year 2000. The global picture

2001 • 2,206 citations

Bladder Cancer Incidence and Mortality: A Global Overview and Recent Trends

2016 • 2,194 citations

EAU Guidelines on Non–Muscle-invasive Urothelial Carcinoma of the Bladder: Update 2016

2016 • 2,126 citations

Changing patterns in the incidence of esophageal and gastric carcinoma in the United States

1998 • 2,080 citations

Breast Cancer Statistics

2012 • 1,951 citations

Annual report to the nation on the status of cancer, 1975‐2006, featuring colorectal cancer trends and impact of interventions (risk factors, screening, and treatment) to reduce future rates

2009 • 1,904 citations

Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies

2019 • 1,869 citations

Universal Hepatitis B Vaccination in Taiwan and the Incidence of Hepatocellular Carcinoma in Children

1997 • 1,836 citations

Trends in Thyroid Cancer Incidence and Mortality in the United States, 1974-2013

2017 • 1,798 citations

The impact of the COVID-19 pandemic on cancer deaths due to delays in diagnosis in England, UK: a national, population-based, modelling study

2020 • 1,698 citations

Colorectal cancer screening for average‐risk adults: 2018 guideline update from the American Cancer Society

2018 • 1,581 citations

The ever‐increasing importance of cancer as a leading cause of premature death worldwide

2021 • 1,536 citations

Efficacy of HPV-based screening for prevention of invasive cervical cancer: follow-up of four European randomised controlled trials

2013 • 1,523 citations

Breast Cancer Screening for Women at Average Risk

2015 • 1,477 citations

International Variation in Prostate Cancer Incidence and Mortality Rates

2012 • 1,458 citations

Global burden of cancers attributable to infections in 2012: a synthetic analysis

2016 • 1,424 citations

Cancer incidence and mortality in relation to body mass index in the Million Women Study: cohort study

2007 • 1,422 citations

The benefits and harms of breast cancer screening: an independent review

2012 • 1,358 citations

Proportion and number of cancer cases and deaths attributable to potentially modifiable risk factors in the United States

2017 • 1,293 citations

Global Burden of 5 Major Types of Gastrointestinal Cancer

2020 • 1,281 citations

Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2012

2015 • 1,171 citations

Daclatasvir plus Sofosbuvir for Previously Treated or Untreated Chronic HCV Infection

2014 • 1,155 citations

EAU Guidelines on Non–Muscle-invasive Urothelial Carcinoma of the Bladder: Update 2013

2013 • 1,133 citations

Colorectal cancer screening: a global overview of existing programmes

2015 • 1,096 citations

Global Cancer in Women: Burden and Trends

2017 • 1,096 citations

Screening for Prostate Cancer

2018 • 1,095 citations

Alcohol consumption and site-specific cancer risk: a comprehensive dose–response meta-analysis

2014 • 1,023 citations

Alleviating the access abyss in palliative care and pain relief—an imperative of universal health coverage: the Lancet Commission report

2017 • 987 citations

Recent Global Patterns in Prostate Cancer Incidence and Mortality Rates

2019 • 984 citations

The changing global patterns of female breast cancer incidence and mortality

2004 • 967 citations

HPV Vaccination and the Risk of Invasive Cervical Cancer

2020 • 965 citations

American Cancer Society Guideline for the Early Detection of Prostate Cancer: Update 2010

2010 • 926 citations

Coronavirus Disease 2019 (COVID-19) Pandemic

2023 • 820 citations

Progress in cancer survival, mortality, and incidence in seven high-income countries 1995–2014 (ICBP SURVMARK-2): a population-based study

2019 • 820 citations

THE DECLINE IN GASTRIC CANCER: EPIDEMIOLOGY OF AN UNPLANNED TRIUMPH

1986 • 810 citations

Global burden of gastric cancer attributable toHelicobacterpylori

2014 • 778 citations

Cervical cancer screening for individuals at average risk: 2020 guideline update from the American Cancer Society

2020 • 724 citations

WHO position paper on mammography screening

2015 • 686 citations

Outdoor air pollution and cancer: An overview of the current evidence and public health recommendations

2020 • 629 citations

Liver Cancer: Connections with Obesity, Fatty Liver, and Cirrhosis

2015 • 622 citations

Increasing incidence of colorectal cancer in young adults in Europe over the last 25 years

2019 • 616 citations

Global cancer patterns: causes and prevention

2013 • 609 citations

Detecting cervical precancer and reaching underscreened women by using HPV testing on self samples: updated meta-analyses

2018 • 608 citations

International Patterns and Trends in Endometrial Cancer Incidence, 1978–2013

2017 • 608 citations

Global burden and trends in premenopausal and postmenopausal breast cancer: a population-based study

2020 • 607 citations

Global patterns and trends in colorectal cancer incidence in young adults

2019 • 602 citations

Impact of HPV vaccination and cervical screening on cervical cancer elimination: a comparative modelling analysis in 78 low-income and lower-middle-income countries

2020 • 597 citations

Global trends in breast cancer incidence and mortality 1973–1997

2005 • 571 citations

International trends in the incidence of malignant melanoma 1953–2008—are recent generations at higher or lower risk?

2012 • 570 citations

The Growing Burden of Invasive Melanoma: Projections of Incidence Rates and Numbers of New Cases in Six Susceptible Populations through 2031

2016 • 531 citations

Stages of the cigarette epidemic on entering its second century

2012 • 519 citations

Avoidable global cancer deaths and total deaths from smoking

2009 • 499 citations

Colorectal cancer population screening programs worldwide in 2016: An update

2017 • 497 citations

Screening for Prostate Cancer: U.S. Preventive Services Task Force Recommendation Statement

2008 • 482 citations

Emerging cancer trends among young adults in the USA: analysis of a population-based cancer registry

2019 • 458 citations

Global Incidence and Mortality for Prostate Cancer: Analysis of Temporal Patterns and Trends in 36 Countries

2016 • 457 citations

International trends in hepatocellular carcinoma incidence, 1978–2012

2019 • 445 citations

Breast Cancer Incidence, 1980 2006: Combined Roles of Menopausal Hormone Therapy, Screening Mammography, and Estrogen Receptor Status

2007 • 443 citations

Accelerating the elimination of viral hepatitis: a Lancet Gastroenterology & Hepatology Commission

2019 • 441 citations

A War on Two Fronts: Cancer Care in the Time of COVID-19

2020 • 420 citations

Mortality impact of achieving WHO cervical cancer elimination targets: a comparative modelling analysis in 78 low-income and lower-middle-income countries

2020 • 417 citations

Prolonged lung cancer screening reduced 10-year mortality in the MILD trial: new confirmation of lung cancer screening efficacy

2019 • 409 citations

Quantifying the role of PSA screening in the US prostate cancer mortality decline

2007 • 401 citations

Increasing incidence of adenocarcinoma of the gastric cardia and adjacent sites

1990 • 400 citations

Overdiagnosis in Mammographic Screening for Breast Cancer in Europe: A Literature Review

2012 • 392 citations

More deaths from pancreatic cancer than breast cancer in the EU by 2017

2016 • 379 citations

Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2016

2019 • 378 citations

Incidence Trends of Adenocarcinoma of the Cervix in 13 European Countries

2005 • 374 citations

COVID-19 and cancer

2020 • 371 citations

Predicting the Future Burden of Esophageal Cancer by Histological Subtype: International Trends in Incidence up to 2030

2017 • 370 citations

Trends in Cervical Squamous Cell Carcinoma Incidence in 13 European Countries: Changing Risk and the Effects of Screening

2005 • 359 citations

Higher Lung Cancer Incidence in Young Women Than Young Men in the United States

2018 • 359 citations

The global burden of urinary bladder cancer

2008 • 354 citations

Human Development Report 2019

2019 • 349 citations

Changes in colorectal cancer incidence in seven high-income countries: a population-based study

2019 • 347 citations

Lung Cancer Incidence and Mortality with Extended Follow-up in the National Lung Screening Trial

2019 • 345 citations

Body Mass Index and Breast Cancer Risk According to Postmenopausal Estrogen-Progestin Use and Hormone Receptor Status

2013 • 341 citations

Opposing Risks of Gastric Cardia and Noncardia Gastric Adenocarcinomas Associated With Helicobacter pylori Seropositivity

2006 • 327 citations

Is gastric cancer becoming a rare disease? A global assessment of predicted incidence trends to 2035

2020 • 326 citations

Body weight and incidence of breast cancer defined by estrogen and progesterone receptor status—A meta‐analysis

2008 • 304 citations

Stage at diagnosis of breast cancer in sub-Saharan Africa: a systematic review and meta-analysis

2016 • 303 citations

Optimisation of breast cancer management in low-resource and middle-resource countries: executive summary of the Breast Health Global Initiative consensus, 2010

2011 • 301 citations

Infection with Helicobacter pylori.

1996 • 295 citations

Cutaneous ultraviolet exposure and its relationship to the development of skin cancer

2008 • 291 citations

Thyroid cancer: zealous imaging has increased detection and treatment of low risk tumours

2013 • 286 citations

Global patterns and trends in cancers of the lip, tongue and mouth

2020 • 283 citations

Incidence of Breast Cancer in the United States: Current and Future Trends

2011 • 274 citations

Prostate cancer incidence in 43 populations worldwide: An analysis of time trends overall and by age group

2015 • 270 citations

Cancer in Africa 2012

2014 • 267 citations

Pan-Canadian Study of Mammography Screening and Mortality from Breast Cancer

2014 • 266 citations

Breast Tumor Characteristics as Predictors of Mammographic Detection: Comparison of Interval- and Screen-Detected Cancers

1999 • 259 citations

Screening for Thyroid Cancer

2017 • 256 citations

A global view on cancer incidence and national levels of the human development index

2016 • 256 citations

Global Patterns of Prostate Cancer Incidence, Aggressiveness, and Mortality in Men of African Descent

2013 • 240 citations

Intrahepatic cholangiocarcinoma and hepatitis C and B virus infection, alcohol intake, and hepatolithiasis: a case-control study in Italy.

2001 • 236 citations

Cost-effectiveness and Benefit-to-Harm Ratio of Risk-Stratified Screening for Breast Cancer

2018 • 223 citations

European cancer mortality predictions for the year 2019 with focus on breast cancer

2019 • 222 citations

The Epidemic of Thyroid Cancer in the United States: The Role of Endocrinologists and Ultrasounds

2013 • 215 citations

The incidence of fatal breast cancer measures the increased effectiveness of therapy in women participating in mammography screening

2018 • 209 citations

Lung cancer incidence in young women vs. young men: A systematic analysis in 40 countries

2020 • 209 citations

Global trends in intrahepatic and extrahepatic cholangiocarcinoma incidence from 1993 to 2012

2020 • 208 citations

Prevalence of cervical disease at age 20 after immunisation with bivalent HPV vaccine at age 12-13 in Scotland: retrospective population study

2019 • 207 citations

The Changing Face of Noncardia Gastric Cancer Incidence Among US Non-Hispanic Whites

2017 • 205 citations

Trends in Colorectal Cancer Incidence Rates in the United States by Tumor Location and Stage, 1992–2008

2012 • 202 citations

Interpreting Trends in Prostate Cancer Incidence and Mortality in the Five Nordic Countries

2007 • 200 citations

Brief Review on COVID-19: The 2020 Pandemic Caused by SARS-CoV-2

2020 • 200 citations

Prevalence of Differentiated Thyroid Cancer in Autopsy Studies Over Six Decades: A Meta-Analysis

2016 • 189 citations

Risk factors for intrahepatic cholangiocarcinoma in a low‐risk population: A nationwide case‐control study

2006 • 188 citations

HPV-FASTER: broadening the scope for prevention of HPV-related cancer

2015 • 188 citations

Biologic Characteristics of Interval and Screen-Detected Breast Cancers

2000 • 184 citations

Screening for Founder Mutations in BRCA1 and BRCA2 in Unselected Jewish Women

2009 • 183 citations

Breast cancer survival in sub‐Saharan Africa by age, stage at diagnosis and human development index: A population‐based registry study

2019 • 180 citations

Global Trends of Bladder Cancer Incidence and Mortality, and Their Associations with Tobacco Use and Gross Domestic Product Per Capita

2020 • 173 citations

Cost-effectiveness of cervical cancer screening methods in low- and middle-income countries: A systematic review

2017 • 172 citations

Costs, affordability, and feasibility of an essential package of cancer control interventions in low-income and middle-income countries: key messages from Disease Control Priorities, 3rd edition

2015 • 170 citations

Risk factors for intrahepatic and extrahepatic cholangiocarcinoma in the United States: A population-based study in SEER-Medicare

2017 • 169 citations

Global Inequalities in Cervical Cancer Incidence and Mortality are Linked to Deprivation, Low Socioeconomic Status, and Human Development

2012 • 165 citations

Hepatitis C: global epidemiology and strategies for control

2016 • 163 citations

Indoor air pollution and risk of lung cancer among Chinese female non-smokers

2013 • 160 citations

Convergence of decreasing male and increasing female incidence rates in major tobacco-related cancers in Europe in 1988–2010

2013 • 158 citations

Trends in cervical cancer incidence in sub-Saharan Africa

2020 • 157 citations

Progress towards elimination goals for viral hepatitis

2020 • 157 citations

Acceptability and feasibility of a screen-and-treat programme for hepatitis B virus infection in The Gambia: the Prevention of Liver Fibrosis and Cancer in Africa (PROLIFICA) study

2016 • 156 citations

Update on mammography trends

2010 • 147 citations

Heterogeneity in the Helicobacter pylori vacA and cagA genes: association with gastroduodenal disease in South Africa?

1999 • 146 citations

Divergent trends for gastric cancer incidence by anatomical subsite in US adults

2011 • 142 citations

Cervical cancer in Africa, Latin America and the Caribbean and Asia: Regional inequalities and changing trends

2017 • 141 citations

Prostate cancer screening with prostate-specific antigen (PSA) test: a clinical practice guideline

2018 • 139 citations

Breast cancer survival and survival gap apportionment in sub-Saharan Africa (ABC-DO): a prospective cohort study

2020 • 139 citations

The Cancer Transition in Japan since 1951

2002 • 136 citations

Increased incidence and survival for oesophageal cancer but not for gastric cardia cancer in the Netherlands

2012 • 135 citations

Trends in stage‐specific incidence rates for urothelial carcinoma of the bladder in the United States: 1988 to 2006

2013 • 134 citations

Global patterns and trends in the incidence of non-Hodgkin lymphoma

2019 • 132 citations

Why cancer screening has never been shown to “save lives”—and what we can do about it

2016 • 128 citations

Informing etiologic research priorities for squamous cell esophageal cancer in Africa: A review of setting‐specific exposures to known and putative risk factors

2016 • 126 citations

Cancer patterns, trends and projections in Latin America and the Caribbean: a global context

2016 • 125 citations

New Systematic Therapies and Trends in Cutaneous Melanoma Deaths Among US Whites, 1986–2016

2020 • 124 citations

Lifetime Prevalence of Cervical Cancer Screening in 55 Low- and Middle-Income Countries

2020 • 124 citations

Prostate Cancer Incidence 5 Years After US Preventive Services Task Force Recommendations Against Screening

2020 • 118 citations

Profiling global cancer incidence and mortality by socioeconomic development

2020 • 115 citations

The Epidemic of Non–Hodgkin Lymphoma in the United States: Disentangling the Effect of HIV, 1992–2009

2013 • 110 citations

Impact of Overweight and Obesity on US Papillary Thyroid Cancer Incidence Trends (1995–2015)

2019 • 109 citations

Patterns and Trends in Human Papillomavirus-Related Diseases in Central and Eastern Europe and Central Asia

2013 • 107 citations

Thyroid cancer “epidemic” also occurs in low- and middle-income countries

2018 • 97 citations

Understanding the ever-changing incidence of thyroid cancer

2020 • 95 citations

Early detection and treatment strategies for breast cancer in low-income and upper middle-income countries: a modelling study

2018 • 94 citations

The Breast Health Global Initiative 2018 Global Summit on Improving Breast Healthcare Through Resource‐Stratified Phased Implementation: Methods and overview

2020 • 92 citations

Liver Fluke-Associated Biliary Tract Cancer

2017 • 92 citations

Relationship between type of smokeless tobacco & risk of cancer: A systematic review

2018 • 90 citations

Human Papillomaviruses

2008 • 88 citations

Declining Lung Cancer Rates Among Young Men and Women in the United States: A Cohort Analysis

1989 • 86 citations

Epidemiology of Squamous Cell Carcinoma of the Lip in the United States

2016 • 85 citations

The evolving epidemic of breast cancer in <scp>sub‐Saharan</scp> Africa: Results from the African Cancer Registry Network

2020 • 85 citations

Comparative Validation of Breast Cancer Risk Prediction Models and Projections for Future Risk Stratification

2019 • 84 citations

Towards skin cancer prevention and early detection: evolution of skin cancer awareness campaigns in Australia

2014 • 82 citations

Prevention of cervical cancer in rural China: Evaluation of HPV vaccination and primary HPV screening strategies

2011 • 77 citations

Cost-effectiveness studies of HPV self-sampling: A systematic review

2020 • 73 citations

Effectiveness of clinical breast examination as a ‘stand-alone’ screening modality: an overview of systematic reviews

2020 • 72 citations

Emerging cancer incidence trends in Canada: The growing burden of young adult cancers

2020 • 68 citations

The health and economic impact of scaling cervical cancer prevention in 50 low‐ and lower‐middle‐income countries

2017 • 64 citations

Cervical cancer burden in Latin America and the Caribbean: Where are we?

2020 • 64 citations

Cancer Epidemiology and Prevention

2018 • 63 citations

Cancer incidence and cancer control in <scp>M</scp>ongolia: Results from the <scp>N</scp>ational <scp>C</scp>ancer <scp>R</scp>egistry 2008–12

2016 • 61 citations

Cancer Screening During the Coronavirus Disease-2019 Pandemic: A Perspective From the National Cancer Institute’s PROSPR Consortium

2020 • 58 citations

Rising Prostate Cancer Incidence in Sub-Saharan Africa: A Trend Analysis of Data from the African Cancer Registry Network

2020 • 58 citations

Scaling up proven innovative cervical cancer screening strategies: Challenges and opportunities in implementation at the population level in low‐ and lower‐middle‐income countries

2017 • 57 citations

Increasing risk of uterine cervical cancer among young Japanese women: Comparison of incidence trends in Japan, South Korea and Japanese‐Americans between 1985 and 2012

2018 • 55 citations

Divergent estrogen receptor‐positive and ‐negative breast cancer trends and etiologic heterogeneity in Denmark

2013 • 55 citations

Personalised medicine and population health: breast and ovarian cancer

2018 • 54 citations

Distinct temporal trends in breast cancer incidence from 1997 to 2016 by molecular subtypes: a population-based study of Scottish cancer registry data

2020 • 40 citations

Influence of Nomenclature Changes on Trends in Papillary Thyroid Cancer Incidence in the United States, 2000 to 2017

2020 • 38 citations

Risk-Adapted Starting Age of Screening for Relatives of Patients With Breast Cancer

2019 • 38 citations

Current and emerging systemic therapies for cutaneous metastatic melanoma

2019 • 38 citations

Is the recent increase in cervical cancer in women aged 20–24 years in England a cause for concern?

2017 • 37 citations

Lung cancer incidence trends in Uruguay 1990–2014: An age-period-cohort analysis

2018 • 33 citations

Divergent oestrogen receptor-specific breast cancer trends in Ireland (2004–2013): Amassing data from independent Western populations provide etiologic clues

2017 • 32 citations

Thyroid Cancer Incidence in India Between 2006 and 2014 and Impact of Overdiagnosis

2020 • 32 citations

Long-term strategies for thyroid health monitoring after nuclear accidents: recommendations from an Expert Group convened by IARC

2018 • 31 citations

Changes in thyroid cancer incidence, post‐2009 <scp>A</scp>merican Thyroid <scp>A</scp>ssociation guidelines

2017 • 30 citations

The impact of the United States Preventive Services Task Force (<scp>USPTSTF</scp>) recommendations against prostate‐specific antigen (<scp>PSA</scp>) testing on <scp>PSA</scp> testing in Australia

2016 • 26 citations

Disease burden of human papillomavirus infection in the Netherlands, 1989–2014: the gap between females and males is diminishing

2017 • 24 citations

Estimation of overdiagnosis using short-term trends and lead time estimates uncontaminated by overdiagnosed cases: Results from the Norwegian Breast Screening Programme

2016 • 24 citations

The Gastric Cardia Is Not a Target for Human Papillomavirus–Induced Carcinogenesis

2010 • 15 citations

INTERNATIONAL SYMPOSIUM ON END RESULTS OF CANCER THERAPY. COMPUTATION OF SURVIVAL RATES.

1964 • 8 citations

Phased implementation for breast cancer management in low‐income and middle‐income countries: A proposal for the strategic application of resource‐stratified guidelines by the Breast Health Global Initiative

2020 • 6 citations

Framework for Understanding Cancer Prevention

2017 • 6 citations

Cited By (0)

No citing papers found in database