Back to search

Liver Fluke-Associated Biliary Tract Cancer

Data up to Jan 2025

Published2017
Citations92
References95

Total Citations Per Year

Abstract

References (95)

Risk factors for cholangiocarcinoma

2011 • 859 citations

Management Strategies in Resection for Hilar Cholangiocarcinoma

1992 • 769 citations

Food-Borne Trematodiases

2009 • 583 citations

Cholangiocarcinoma: lessons from Thailand

2008 • 485 citations

The tumorigenic liver fluke Opisthorchis viverrini – multiple pathways to cancer

2012 • 422 citations

The current status of opisthorchiasis and clonorchiasis in the Mekong Basin

2011 • 364 citations

Impact of Classification of Hilar Cholangiocarcinomas (Klatskin Tumors) on the Incidence of Intra- and Extrahepatic Cholangiocarcinoma in the United States

2006 • 349 citations

Opisthorchiasis and Opisthorchis-associated cholangiocarcinoma in Thailand and Laos

2010 • 313 citations

The Drugs We Have and the Drugs We Need Against Major Helminth Infections

2010 • 284 citations

Epidemiology of Opisthorchis viverrini

2003 • 256 citations

Update on the Diagnosis and Treatment of Cholangiocarcinoma

2017 • 204 citations

Cholangiocarcinoma: Update and future perspectives

2010 • 186 citations

A Granulin-Like Growth Factor Secreted by the Carcinogenic Liver Fluke, Opisthorchis viverrini, Promotes Proliferation of Host Cells

2009 • 180 citations

Mechanism of NO-mediated oxidative and nitrative DNA damage in hamsters infected with Opisthorchis viverrini: a model of inflammation-mediated carcinogenesis

2004 • 177 citations

Pathobiology of opisthorchiasis: an update

2003 • 163 citations

The Opisthorchis viverrini genome provides insights into life in the bile duct

2014 • 162 citations

Opisthorchis viverrini: The carcinogenic human liver fluke

2008 • 155 citations

Carcinogenic Liver Fluke Secretes Extracellular Vesicles That Promote Cholangiocytes to Adopt a Tumorigenic Phenotype

2015 • 155 citations

Advanced periductal fibrosis from infection with the carcinogenic human liver fluke Opisthorchis viverrini correlates with elevated levels of interleukin-6

2009 • 154 citations

Localisation of parasite antigens and inflammatory responses in experimental opisthorchiasis

2000 • 145 citations

The secreted and surface proteomes of the adult stage of the carcinogenic human liver fluke Opisthorchis viverrini

2010 • 140 citations

Infection with the carcinogenic liver fluke Opisthorchis viverrini modifies intestinal and biliary microbiome

2013 • 129 citations

Toward integrated opisthorchiasis control in northeast Thailand: The Lawa project

2014 • 129 citations

Cholangiocarcinoma: A compact review of the literature

2008 • 126 citations

Relationship between faecal egg count and worm burden of Opisthorchis viverrini in human autopsy cases

1991 • 109 citations

Tissue Microbiome Profiling Identifies an Enrichment of Specific Enteric Bacteria in Opisthorchis viverrini Associated Cholangiocarcinoma

2016 • 104 citations

Elevated Plasma IL-6 Associates with Increased Risk of Advanced Fibrosis and Cholangiocarcinoma in Individuals Infected by Opisthorchis viverrini

2012 • 103 citations

Interleukin-6-driven progranulin expression increases cholangiocarcinoma growth by an Akt-dependent mechanism

2011 • 103 citations

Opisthorchiasis from Imported Raw Fish

2004 • 101 citations

PCR Diagnosis of Opisthorchis viverrini and Haplorchis taichui Infections in a Lao Community in an Area of Endemicity and Comparison of Diagnostic Methods for Parasitological Field Surveys

2009 • 92 citations

iNOS‐dependent DNA damage via NF‐κB expression in hamsters infected with Opisthorchis viverrini and its suppression by the antihelminthic drug praziquantel

2006 • 89 citations

Incidence Rates of Intra- and Extrahepatic Cholangiocarcinomas in Denmark From 1978 Through 2002

2007 • 85 citations

Immune responsiveness and parasite-specific antibody levels in human hepatobiliary disease associated with Opisthorchis viverrini infection

1991 • 84 citations

Efficacy and safety of mefloquine, artesunate, mefloquine–artesunate, tribendimidine, and praziquantel in patients with Opisthorchis viverrini: a randomised, exploratory, open-label, phase 2 trial

2010 • 83 citations

Increased cell proliferation of mouse fibroblast NIH-3T3 in vitro induced by excretory/secretory product(s) from Opisthorchis viverrini

2004 • 80 citations

Improvement of PCR for Detection of Opisthorchis viverrini DNA in Human Stool Samples

2007 • 79 citations

Opisthorchis viverrini excretory/secretory products induce toll-like receptor 4 upregulation and production of interleukin 6 and 8 in cholangiocyte

2010 • 78 citations

Evaluation of a Monoclonal Antibody-Based Enzyme-Linked Immunosorbent Assay for the Diagnosis of Opisthorchis viverrini Infection in an Endemic Area

1995 • 77 citations

High prevalence of liver and intestinal fluke infections among residents of Savannakhet Province in Laos

2007 • 76 citations

Opisthorchis viverrini : intensity and rates of infection in cyprinoid fish from an endemic focus in Northeast Thailand.

1982 • 75 citations

Liver fluke infection and cholangiocarcinoma: a review

2016 • 73 citations

Advances in the Diagnosis of Human Opisthorchiasis: Development of Opisthorchis viverrini Antigen Detection in Urine

2015 • 69 citations

Helicobacter pylori in Thai patients with cholangiocarcinoma and its association with biliary inflammation and proliferation

2012 • 66 citations

Evaluation of PCR based coprodiagnosis of human opisthorchiasis

2005 • 65 citations

The ecology of the Bithynia first intermediate hosts of Opisthorchis viverrini

2011 • 65 citations

The Carcinogenic Liver Fluke Opisthorchis viverrini is a Reservoir for Species of Helicobacter

2015 • 62 citations

Comparative studies on the morphology of the eggs of Opisthorchis viverrini and lecithodendriid trematodes.

1991 • 61 citations

Oxidative and Nitrative Stress in Opisthorchis viverrini–Infected Hamsters: An Indirect Effect after Praziquantel Treatment

2008 • 60 citations

The Lawa model: A sustainable, integrated opisthorchiasis control program using the EcoHealth approach in the Lawa Lake region of Thailand

2016 • 60 citations

Efficacy and Safety of Tribendimidine Against Clonorchis sinensis

2012 • 56 citations

Proliferative effects of excretory/secretory products from Clonorchis sinensis on the human epithelial cell line HEK293 via regulation of the transcription factor E2F1

2007 • 54 citations

Genetics of Opisthorchis viverrini-related cholangiocarcinoma

2015 • 51 citations

Free radicals enzymatically triggered by Clonorchis sinensis excretory–secretory products cause NF-κB-mediated inflammation in human cholangiocarcinoma cells

2011 • 51 citations

Excretory/secretory products of the carcinogenic liver fluke are endocytosed by human cholangiocytes and drive cell proliferation and IL6 production

2015 • 48 citations

Opisthorchis viverrini antigen induces the expression of Toll-like receptor 2 in macrophage RAW cell line

2005 • 47 citations

Trends in liver cancer incidence between 1985 and 2009, Khon Kaen, Thailand: cholangiocarcinoma.

2011 • 47 citations

Differential gene expression profiling in human cholangiocarcinoma cells treated with Clonorchis sinensis excretory-secretory products

2008 • 42 citations

Co-infections with liver fluke and Helicobacter species: A paradigm change in pathogenesis of opisthorchiasis and cholangiocarcinoma?

2016 • 41 citations

Prevalence of Opisthorchis viverrini infection in the canine and feline hosts in three villages, Khon Kaen Province, northeastern Thailand.

2010 • 40 citations

Apoptosis of cholangiocytes modulated by thioredoxin of carcinogenic liver fluke

2015 • 39 citations

Gene expression profiling defined pathways correlated with fibroblast cell proliferation induced by Opisthorchis viverrini excretory/secretory product

2006 • 39 citations

Induction of cancer-related microRNA expression profiling using excretory-secretory products of Clonorchis sinensis

2014 • 38 citations

Modeling impacts of climate change on the potential distribution of the carcinogenic liver fluke, Opisthorchis viverrini, in Thailand

2016 • 38 citations

A microRNA profile associated with Opisthorchis viverrini-induced cholangiocarcinoma in tissue and plasma

2015 • 38 citations

Resistance of cholangiocarcinoma cells to parthenolide-induced apoptosis by the excretory–secretory products of Clonorchis sinensis

2008 • 37 citations

Diagnostic values of parasite-specific antibody detections in saliva and urine in comparison with serum in opisthorchiasis

2011 • 36 citations

Review and Current Status of Opisthorchis viverrini Infection at the Community Level in Thailand

2015 • 35 citations

Efficacy and Safety of Praziquantel, Tribendimidine and Mebendazole in Patients with Co-infection of Clonorchis sinensis and Other Helminths

2014 • 35 citations

Expression, refolding and purification of Ov-GRN-1, a granulin-like growth factor from the carcinogenic liver fluke, that causes proliferation of mammalian host cells

2011 • 35 citations

Coinfection with Helicobacter pylori and Opisthorchis viverrini Enhances the Severity of Hepatobiliary Abnormalities in Hamsters

2017 • 34 citations

Expression of Toll-like receptor (TLR) 2 and TLR4 in the livers of mice infected by Clonorchis sinensis

2015 • 34 citations

Association between praziquantel treatment and cholangiocarcinoma: a hospital-based matched case–control study

2015 • 33 citations

Multiplex Real-Time PCR Assay Targeting Eight Parasites Customized to the Korean Population: Potential Use for Detection in Diarrheal Stool Samples from Gastroenteritis Patients

2016 • 33 citations

Oxidative stress-mediated mouse liver lesions caused by Clonorchis sinensis infection

2015 • 32 citations

Detection of Clonorchis sinensis Circulating Antigen in Sera from Chinese Patients by Immunomagnetic Bead ELISA Based on IgY

2014 • 30 citations

Suppression of Ov-grn-1 encoding granulin of Opisthorchis viverrini inhibits proliferation of biliary epithelial cells

2014 • 30 citations

Comparative Morphology of Minute Intestinal Fluke Eggs That Can Occur in Human Stools in the Republic of Korea

2012 • 29 citations

Seasonal and Spatial Environmental Influence on Opisthorchis viverrini Intermediate Hosts, Abundance, and Distribution: Insights on Transmission Dynamics and Sustainable Control

2016 • 28 citations

Improved performance and quantitative detection of copro-antigens by a monoclonal antibody based ELISA to diagnose human opisthorchiasis

2013 • 28 citations

Risk of cholangiocarcinoma in patients with primary sclerosing cholangitis

2017 • 27 citations

Opisthorchis viverrini: Detection by polymerase chain reaction (PCR) in human stool samples

2008 • 27 citations

Efficacy and safety of tribendimidine against Opisthorchis viverrini : two randomised, parallel-group, single-blind, dose-ranging, phase 2 trials

2016 • 26 citations

Molecular expression and enzymatic characterization of thioredoxin from the carcinogenic human liver fluke Opisthorchis viverrini

2011 • 24 citations

Secreted Opisthorchis viverrini glutathione S-transferase regulates cell proliferation through AKT and ERK pathways in cholangiocarcinoma

2011 • 24 citations

Clonorchis sinensis ferritin heavy chain triggers free radicals and mediates inflammation signaling in human hepatic stellate cells

2014 • 23 citations

Development of a PCR assay and pyrosequencing for identification of important human fish-borne trematodes and its potential use for detection in fecal specimens

2014 • 22 citations

Detection of salivary antibodies to crude antigens of Opisthorchis viverrini in opisthorchiasis and cholangiocarcinoma patients

2010 • 22 citations

Immunodiagnosis of opisthorchiasis using parasite cathepsin F

2015 • 22 citations

Proteomic characterization of the internalization of Opisthorchis viverrini excretory/secretory products in human cells

2016 • 20 citations

Uncovering the Pathogenic Landscape of Helminth (Opisthorchis viverrini) Infections: A Cross-Sectional Study on Contributions of Physical and Social Environment and Healthcare Interventions

2016 • 15 citations

Development of a PCR Assay for Diagnosing Trematode ( Opisthorchis and Haplorchis ) Infections in Human Stools

2016 • 14 citations

Toll-Like Receptor-Mediated Free Radical Generation in Clonorchis sinensis Excretory-Secretory Product-Treated Cholangiocarcinoma Cells

2016 • 13 citations

Decreased risk of cholangiocarcinogenesis following repeated cycles of Opisthorchis viverrini infection-praziquantel treatment: Magnetic Resonance Imaging (MRI) and histopathological study in a hamster model

2016 • 13 citations

Association between Opisthorchis viverrini and Leptospira spp. infection in endemic Northeast Thailand

2016 • 10 citations

The miRNAome of Opisthorchis viverrini induced intrahepatic cholangiocarcinoma

2014 • 7 citations

Cited By (0)

No citing papers found in database

Liver Fluke-Associated Biliary Tract Cancer (2017) – Gut and Liver | Metascience Observatory Explorer