A yeast nucleolar protein related to mammalian fibrillarin is associated with small nucleolar RNA and is essential for viability.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene.

1975 • 3,483 citations

[12] One-step gene disruption in yeast

1983 • 3,302 citations

Empirical Predictions of Protein Conformation

1978 • 3,167 citations

Rat monoclonal antitubulin antibodies derived by using a new nonsecreting rat cell line.

1982 • 923 citations

A common RNA recognition motif identified within a defined U1 RNA binding domain of the 70K U1 snRNP protein

1989 • 601 citations

SINGLE-STRANDED DNA BINDING PROTEINS REQUIRED FOR DNA REPLICATION

1986 • 563 citations

Fibrillarin: a new protein of the nucleolus identified by autoimmune sera

1985 • 488 citations

Heterogeneous nuclear ribonucleoprotein particles and the pathway of mRNA formation

1988 • 401 citations

U3, U8 and U13 comprise a new class of mammalian snRNPs localized in the cell nucleolus.

1989 • 391 citations

Nucleolar Structure

1984 • 333 citations

Synthesis of ribosomes in Saccharomyces cerevisiae

1989 • 331 citations

Localization of RNA polymerase I in interphase cells and mitotic chromosomes by light and electron microscopic immunocytochemistry.

1984 • 313 citations

A yeast small nuclear RNA is required for normal processing of pre-ribosomal RNA.

1987 • 313 citations

Nuclear segregation of U2 snRNA requires binding of specific snRNP proteins

1985 • 307 citations

Purification and partial characterization of a nucleolar scleroderma antigen (Mr = 34,000; pI, 8.5) rich in NG,NG-dimethylarginine.

1985 • 282 citations

Silver staining, immunofluorescence, and immunoelectron microscopic localization of nucleolar phosphoproteins B23 and C23

1984 • 279 citations

A constitutive nucleolar protein identified as a member of the nucleoplasmin family.

1987 • 267 citations

Identification and characterization of a yeast nucleolar protein that is similar to a rat liver nucleolar protein.

1988 • 240 citations

Localization of nucleolar phosphoproteins B23 and C23 during mitosis

1983 • 230 citations

Control of microtubule nucleation and stability in Madin-Darby canine kidney cells: the occurrence of noncentrosomal, stable detyrosinated microtubules.

1987 • 199 citations

At the heart of the nucleolus

1987 • 197 citations

Structural analysis of the human U3 ribonucleoprotein particle reveal a conserved sequence available for base pairing with pre-rRNA.

1987 • 190 citations

Structure of rodent helix-destabilizing protein revealed by cDNA cloning.

1986 • 173 citations

Fungal small nuclear ribonucleoproteins share properties with plant and vertebrate U-snRNPs.

1987 • 171 citations

A Proposed Model for Interaction of Polypeptides with RNA

1974 • 165 citations

The yeast homologue of U3 snRNA.

1987 • 160 citations

A novel nucleoskeletal-like protein located at the nuclear periphery is required for the life cycle of Saccharomyces cerevisiae.

1988 • 156 citations

Clustering of glycine and NG,NG-dimethylarginine in nucleolar protein C23

1985 • 134 citations

Nucleologenesis: Composition and fate of prenucleolar bodies

1985 • 134 citations

Yeast contains small nuclear RNAs encoded by single copy genes

1983 • 133 citations

Human autoantibodies: probes for nucleolus structure and function

1987 • 128 citations

Saccharomyces cerevisiae SSB1 protein and its relationship to nucleolar RNA-binding proteins.

1987 • 116 citations

Does the synthesis of ribosomal RNA take place‐within nucleolar fibrillar centers or dense fibrillar components?

1989 • 110 citations

Protein and cDNA sequence of a glycine-rich, dimethylarginine-containing region located near the carboxyl-terminal end of nucleolin (C23 and 100 kDa).

1986 • 109 citations

Structure of the mouse nucleolin gene

1988 • 102 citations

Characterization of an SNR gene locus in Saccharomyces cerevisiae that specifies both dispensible and essential small nuclear RNAs.

1988 • 100 citations

Localization of ribosomal protein S1 in the granular component of the interphase nucleolus and its distribution during mitosis.

1985 • 90 citations

Ribocharin: a nuclear Mr 40,000 protein specific to precursor particles of the large ribosomal subunit

1985 • 90 citations

Structural Analysis of the Human U3 Ribonucleoprotein Particle Reveal a Conserved Sequence Available for Base Pairing with Pre-rRna

1987 • 88 citations

Nucleolar and nuclear envelope proteins of the yeast Saccharomyces cerevisiae.

1988 • 86 citations

Genetic analysis of small nuclear RNAs in Saccharomyces cerevisiae: viable sextuple mutant.

1988 • 82 citations

Deletion of a yeast small nuclear RNA gene impairs growth.

1985 • 79 citations

Nuclear Function and Organization: The Potential of Immunochemical Approaches

1988 • 79 citations

A U4-like small nuclear RNA is dispensable in yeast

1983 • 68 citations

The nucleolar protein, B-36, contains a glycine and dimethylarginine-rich sequence conserved in several other nuclear RNA-binding proteins

1988 • 53 citations

Immunolocalization of the 100 kDa nucleolar protein during the mitotic cycle in CHO cells

1985 • 50 citations

Saccharomyces Cerevisiae SSB1 Protein and its Relationship to Nucleolar RNA-Binding Proteins

1987 • 50 citations

Micropreparative separation of peptides derived from sodium dodecyl sulphate-solubilized proteins

1989 • 48 citations

Characterization of an SNR Gene Locus in Saccharomyces cerevisiae That Specifies Both Dispensible and Essential Small Nuclear RNAs

1988 • 47 citations

Nucleolar function of the dense crescent in the yeast nucleus

1973 • 40 citations

Characterization of the nucleolar protein, B-36, using monoclonal antibodies

1986 • 38 citations

Genetic Analysis of Small Nuclear RNAs in Saccharomyces cerevisiae: Viable Sextuple Mutant

1988 • 34 citations

Isolation of the gene encoding yeast single-stranded nucleic acid binding protein 1.

1986 • 26 citations

Cloning of cDNA encoding a 100 kDa nudeolar protein (nucleoline) of Chinese hamster ovary cells

1985 • 25 citations

Electron microscopic autoradiographic study of RNA synthesis in yeast nucleus

1972 • 22 citations

Immunoelectron microscopic localization of the nucleolar protein B‐36 (fibrillarin) during the cell cycle of Physarum polycephalum

1989 • 22 citations

[21] Isolation of the yeast calmodulin gene using synthetic oligonucleotide probes

1987 • 16 citations