Genetic Analysis of Small Nuclear RNAs in Saccharomyces cerevisiae: Viable Sextuple Mutant

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

Methods in Yeast Genetics

1988 • 4,905 citations

[12] One-step gene disruption in yeast

1983 • 3,302 citations

Mapping adenines, guanines, and pyrimidines in RNA

1977 • 1,391 citations

SPLICING OF MESSENGER RNA PRECURSORS

1986 • 1,233 citations

Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus

1979 • 1,178 citations

The telomere terminal transferase of tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity

1987 • 1,127 citations

PRE-mRNA SPLICING

1986 • 673 citations

The role of small nuclear ribonucleoprotein particles in pre-mRNA splicing

1987 • 594 citations

SnRNAs, SnRNPs, and RNA Processing

1982 • 458 citations

[9] Specific labeling of 3′ termini of RNA with T4 RNA ligase

1980 • 421 citations

Small RNA species of the HeLa cell: Metabolism and subcellular localization

1976 • 409 citations

Lariat structures are in vivo intermediates in yeast pre-mRNA splicing

1984 • 379 citations

Each of three "TATA elements" specifies a subset of the transcription initiation sites at the CYC-1 promoter of Saccharomyces cerevisiae.

1985 • 342 citations

Accurate cleavage and polyadenylation of exogenous RNA substrate

1985 • 334 citations

A yeast small nuclear RNA is required for normal processing of pre-ribosomal RNA.

1987 • 313 citations

Shuttle mutagenesis: a method of transposon mutagenesis for Saccharomyces cerevisiae.

1986 • 306 citations

Functions of the Abundant U-snRNPs

1988 • 284 citations

Formation of the 3′ end of U1 snRNA requires compatible snRNA promoter elements

1986 • 255 citations

Repeated DNA sequences upstream from HIS1 also occur at several other co-regulated genes in Saccharomyces cerevisiae.

1983 • 231 citations

3′ end formation of U1 snRNA precursors is coupled to transcription from snRNA promoters

1986 • 222 citations

The Genes and Transcription of the Major Small Nuclear RNAs

1988 • 199 citations

Low molecular weight RNA associated with 28 s nucleolar RNA

1970 • 198 citations

The cDNA sequences of the sea urchin U7 small nuclear RNA suggest specific contacts between histone mRNA precursor and U7 RNA during RNA processing.

1984 • 173 citations

Fungal small nuclear ribonucleoproteins share properties with plant and vertebrate U-snRNPs.

1987 • 171 citations

An essential yeast snRNA with a U5-like domain is required for splicing in vivo

1987 • 168 citations

Biochemical complementation with RNA in the Xenopus oocyte: A small rna is required for the generation of 3′ histone mRNA termini

1983 • 165 citations

The yeast homologue of U3 snRNA.

1987 • 160 citations

U2 RNA from yeast is unexpectedly large and contains homology to vertebrate U4, U5, and U6 small nuclear RNAs

1986 • 160 citations

A small nuclear ribonucleoprotein associates with the AAUAAA polyadenylation signal in vitro

1986 • 139 citations

Yeast contains small nuclear RNAs encoded by single copy genes

1983 • 133 citations

S. cerevisiae U1 RNA is large and has limited primary sequence homology to metazoan U1 snRNA

1987 • 131 citations

Saccharomyces cerevisiae Has a U1-Like Small Nuclear RNA with Unexpected Properties

1987 • 122 citations

Sequences required for 3′ end formation of human U2 small nuclear RNA

1985 • 122 citations

Small nuclear RNAs from Saccharomyces cerevisiae: unexpected diversity in abundance, size, and molecular complexity.

1986 • 105 citations

An essential snRNA from S. cerevisiae has properties predicted for U4, including interaction with a U6-like snRNA

1987 • 104 citations

Primary and secondary structure of U8 small nuclear RNA.

1985 • 94 citations

RNase III cleavage is obligate for maturation but not for function of Escherichia coli pre-23S rRNA.

1984 • 86 citations

A Subset of Yeast snRNA's Contains Functional Binding Sites for the Highly Conserved Sm Antigen

1987 • 85 citations

Deletion of a yeast small nuclear RNA gene impairs growth.

1985 • 79 citations

The metabolic role of RNases

1988 • 69 citations

A U4-like small nuclear RNA is dispensable in yeast

1983 • 68 citations

Structure and Function of Minor snRNPs

1988 • 57 citations

Introduction

1985 • 53 citations

Small nuclear RNA molecules that regulate nuclease accessibility in specific chromatin regions of meiotic cells

1981 • 49 citations

Finding functions for small nuclear RNAs in yeast

1986 • 40 citations

High level of complexity of small nuclear RNAs in fungi and plants

1987 • 40 citations