Characterization of an SNR gene locus in Saccharomyces cerevisiae that specifies both dispensible and essential small nuclear RNAs.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Methods in yeast genetics

1979 • 7,824 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

Methods in Yeast Genetics

1988 • 4,905 citations

[12] One-step gene disruption in yeast

1983 • 3,302 citations

Determination of nucleic acid sequence homologies and relative concentrations by a dot hybridization procedure

1979 • 1,403 citations

Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus

1979 • 1,178 citations

DNA sequence required for efficient transcription termination in yeast

1982 • 1,014 citations

Charon Phages: Safer Derivatives of Bacteriophage Lambda for DNA Cloning

1977 • 951 citations

A GAL10-CYC1 hybrid yeast promoter identifies the GAL4 regulatory region as an upstream site.

1982 • 575 citations

Recognition of the TACTAAC box during mRNA splicing in yeast involves base pairing to the U2-like snRNA

1987 • 508 citations

SnRNAs, SnRNPs, and RNA Processing

1982 • 458 citations

Multiple factors including the small nuclear ribonucleoproteins U1 and U2 are necessary for Pre-mRNA splicing in vitro

1985 • 442 citations

[9] Specific labeling of 3′ termini of RNA with T4 RNA ligase

1980 • 421 citations

Small RNA species of the HeLa cell: Metabolism and subcellular localization

1976 • 409 citations

The 5′ terminus of the RNA moiety of U1 small nuclear ribonucleoprotein particles is required for the splicing of messenger RNA precursors

1984 • 404 citations

Evidence for an intron-contained sequence required for the splicing of yeast RNA polymerase II transcripts

1983 • 396 citations

Yeast mRNA splicing in vitro.

1985 • 337 citations

A yeast small nuclear RNA is required for normal processing of pre-ribosomal RNA.

1987 • 313 citations

The 3′ Splice Site of Pre-Messenger RNA Is Recognized by a Small Nuclear Ribonucleoprotein

1985 • 310 citations

Nuclear segregation of U2 snRNA requires binding of specific snRNP proteins

1985 • 307 citations

A convenient and adaptable package of computer programs for DNA and protein sequence management, analysis and homology determination

1984 • 285 citations

A comparison of yeast ribosomal protein gene DNA sequences

1984 • 256 citations

Evidence for the biochemical role of an internal sequence in yeast nuclear mRNA introns: Implications for U1 RNA and metazoan mRNA splicing

1983 • 239 citations

U2 RNA shares a structural domain with U1, U4, and U5 RNAs.

1982 • 236 citations

Pre-mRNA splicing in vitro requires intact U4/U6 small nuclear ribonucleoprotein

1986 • 222 citations

Low molecular weight RNA associated with 28 s nucleolar RNA

1970 • 198 citations

U1, U2, and U4/U6 small nuclear ribonucleoproteins are required for in vitro splicing but not polyadenylation

1986 • 192 citations

The cDNA sequences of the sea urchin U7 small nuclear RNA suggest specific contacts between histone mRNA precursor and U7 RNA during RNA processing.

1984 • 173 citations

Fungal small nuclear ribonucleoproteins share properties with plant and vertebrate U-snRNPs.

1987 • 171 citations

An essential yeast snRNA with a U5-like domain is required for splicing in vivo

1987 • 168 citations

U2 RNA from yeast is unexpectedly large and contains homology to vertebrate U4, U5, and U6 small nuclear RNAs

1986 • 160 citations

The yeast homologue of U3 snRNA.

1987 • 160 citations

Purification of snRNPs U1, U2, U4, U5 and U6 with 2,2,7-trimethylguanosine-specific antibody and definition of their constituent proteins reacting with anti-Sm and anti-(U1)RNP antisera.

1983 • 143 citations

Isolation and characterization of rabbit anti-m₃^2,2,7G antibodies

1982 • 135 citations

Yeast contains small nuclear RNAs encoded by single copy genes

1983 • 133 citations

S. cerevisiae U1 RNA is large and has limited primary sequence homology to metazoan U1 snRNA

1987 • 131 citations

Specific small nuclear RNAs are associated with yeast spliceosomes

1986 • 127 citations

Saccharomyces cerevisiae Has a U1-Like Small Nuclear RNA with Unexpected Properties

1987 • 122 citations

Characterization and subcellular localization of 7-8 S RNAs of Novikoff hepatoma.

1981 • 113 citations

Small nuclear RNAs from Saccharomyces cerevisiae: unexpected diversity in abundance, size, and molecular complexity.

1986 • 105 citations

An essential snRNA from S. cerevisiae has properties predicted for U4, including interaction with a U6-like snRNA

1987 • 104 citations

Genetic complementation in the Xenopus oocyte: co-expression of sea urchin histone and U7 RNAs restores 3′ processing of H3 pre-mRNA in the oocyte.

1986 • 96 citations

Primary and secondary structure of U8 small nuclear RNA.

1985 • 94 citations

A Subset of Yeast snRNA's Contains Functional Binding Sites for the Highly Conserved Sm Antigen

1987 • 85 citations

Deletion of a yeast small nuclear RNA gene impairs growth.

1985 • 79 citations

A U4-like small nuclear RNA is dispensable in yeast

1983 • 68 citations

Yeast Nuclear RNA Polymerases and Their Role in Transcription

1982 • 36 citations

Isolation and partial characterization of U1-U6 small RNAs from Bombyx mori

1985 • 35 citations

Simple Mendelian Inheritance of the Repeating Yeast Ribosomal DNA Genes

1978 • 33 citations