Macrophage inflammatory protein 1-alpha is a potential osteoclast stimulatory factor in multiple myeloma

Serum levels of interleukin 6, a potent myeloma cell growth factor, as a reflect of disease severity in plasma cell dyscrasias.

1989 • 501 citations

IL-6 stimulates osteoclast-like multinucleated cell formation in long term human marrow cultures by inducing IL-1 release.

1990 • 493 citations

Production of Lymphotoxin, a Bone-Resorbing Cytokine, by Cultured Human Myeloma Cells

1987 • 386 citations

Human-human hybridomas producing monoclonal antibodies of predefined antigenic specificity.

1980 • 383 citations

Interleukin 6. A potential autocrine/paracrine factor in Paget's disease of bone.

1992 • 363 citations

Production of Free Light Chains of Immunoglobulin by a Hematopoietic Cell Line Derived from a Patient with Multiple Myeloma.

1967 • 294 citations

Monoclonal antibodies to osteoclastomas (giant cell bone tumors): definition of osteoclast-specific cellular antigens.

1985 • 279 citations

Mechanisms of bone destruction in multiple myeloma: the importance of an unbalanced process in determining the severity of lytic bone disease.

1989 • 240 citations

The role of MIP-1α in Inflammation and hematopoiesis

1996 • 218 citations

Production of interleukin-1 by bone marrow myeloma cells

1989 • 191 citations

Production of cytokines by bone marrow cells obtained from patients with multiple myeloma

1989 • 156 citations

Cytokine Network in Human Multiple Myeloma

1992 • 150 citations

Interleukin-1 accelerates autocrine growth of myeloma cells through interleukin-6 in human myeloma

1989 • 141 citations

IL-6 Mediates the Effects of IL-1 or TNF, but Not PTHrP or 1,25(OH)2D3, on Osteoclast-like Cell Formation in Normal Human Bone Marrow Cultures

1998 • 124 citations

Macrophage inflammatory protein-1 alpha and IL-8 stimulate the motility but suppress the resorption of isolated rat osteoclasts.

1995 • 115 citations

PROLIFERATION AND DIFFERENTIATION OF LYMPHOID CELLS: STUDIES WITH HUMAN LYMPHOID CELL LINES AND IMMUNOGLOBULIN SYNTHESIS

1971 • 108 citations

Development of an in vivo model of human multiple myeloma bone disease

1996 • 106 citations

Establishment of a human plasma cell line in vitro.

1978 • 99 citations

Macrophage inflammatory protein-1 alpha (LD78) expressed in human bone marrow: its role in regulation of hematopoiesis and osteoclast recruitment.

1997 • 91 citations

Bone destruction and hypercalcemia in plasma cell myeloma.

1986 • 85 citations

PATHOGENESIS AND MANAGEMENT OF BONE LESIONS IN MULTIPLE MYELOMA

1997 • 65 citations

Osteoclast-like cells formed in long-term human bone marrow cultures express a similar surface phenotype as authentic osteoclasts.

1989 • 55 citations

The incidence and epidemiology of plasma cell neoplasms.

1995 • 54 citations

Establishment and characterization of a human non‐secretory plasmacytoid cell line and its hybridization with human B cells

1983 • 52 citations

Plasma cells induce apoptosis of pre-B cells by interacting with bone marrow stromal cells

1996 • 46 citations

Comparison of the inhibitory effect of AcSDKP, TNF-alpha, TGF-beta, and MIP-1 alpha on marrow-purified CD34+ progenitors.

1995 • 44 citations

Blood stem cell transplantation: From preclinical to clinical models

1995 • 34 citations

Determination of IL6, IL1, and IL4 in the Plasma of Patients with Multiple Myeloma

1994 • 18 citations

Chronic lymphoid leukemias: Recent advances in biology and therapy

1995 • 18 citations

Novel therapeutic strategies.

1999 • 8 citations