The Absorption, Distribution, and Metabolism of Ethanol and Its Effects on Nutrition and Hepatic Function

A JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

1909 • 6,516 citations

Regulation of Hepatic Fatty Acid Oxidation and Ketone Body Production

1980 • 1,430 citations

Research Advances in Alcohol and Drug Problems

1984 • 1,126 citations

3 Alcohol Dehydrogenases

1975 • 706 citations

An Experimental Study of the Etiology of “Rum Fits” and Delirium Tremens

1955 • 518 citations

High Blood Acetaldehyde Levels after Ethanol Administration

1975 • 514 citations

Developmental changes and polymorphism in human alcohol dehydrogenase

1971 • 375 citations

Effects of ethanol on lipid metabolism.

1979 • 374 citations

Biochemistry and Pharmacology of Ethanol

1979 • 353 citations

Vitamin B6 Metabolism in Chronic Alcohol Abuse

1974 • 286 citations

Reconstitution of the microsomal ethanol-oxidizing system. Qualitative and quantitative changes of cytochrome P-450 after chronic ethanol consumption.

1977 • 261 citations

Racial differences in alcohol sensitivity: A new hypothesis

1979 • 259 citations

Alcohol and Aldehyde Metabolizing Systems-IV

1980 • 241 citations

Relationship between facial flushing and blood acetaldehyde levels after alcohol intake

1979 • 221 citations

The characteristics of the ‘peroxidatic’ reaction of catalase in ethanol oxidation

1973 • 195 citations

Pharmacokinetics of Ethanol: A Review

1980 • 177 citations

ALCOHOL AND NUTRITION

1982 • 172 citations

Mechanisms of thiamin deficiency in chronic alcoholism

1980 • 171 citations

The Rate of Ethanol Metabolism in Isolated Rat Hepatocytes

1977 • 167 citations

Effect of ethanol on glutathione concentration in isolated hepatocytes

1980 • 164 citations

Racial Differences in Biological Sensitivity to Ethanol: The Role of Alcohol Dehydrogenase and Aldehyde Dehydrogenase Isozymes

1981 • 160 citations

The kinetics of ethanol absorption and elimination in twins and supplementary repetitive experiments in singleton subjects

1977 • 145 citations

Alcohol, protein metabolism, and liver injury

1980 • 145 citations

Elimination of Alcohol from Human Blood

1976 • 138 citations

Isolation of II-alcohol dehydrogenase of human liver: Is it a determinant of alcoholism?

1977 • 136 citations

Rate‐Limiting Factors in Ethanol Oxidation by Isolated Rat‐Liver Parenchymal Cells

1973 • 130 citations

Metabolism and Metabolic Effects of Alcohol

1984 • 126 citations

Enzymology of Human Alcohol Metabolism

1977 • 125 citations

Optical measurement of the catalase-hydrogen peroxide intermediate (Compound I) in the liver of anaesthetized rats and its implication to hydrogen peroxide production in situ

1975 • 116 citations

ATYPICAL HUMAN LIVER ALCOHOL DEHYDROGENASE

1968 • 116 citations

Food effects on absorption and metabolism of alcohol.

1976 • 115 citations

Attenuation of the ethanol-induced hepatic redox change after chronic alcohol consumption in baboons: Metabolic consequencesin vivo andin vitro

1981 • 115 citations

Problems and Pitfalls in Acetaldehyde Determinations

1980 • 114 citations

Alcohol Metabolism in American Indians and Whites

1976 • 114 citations

Quantitative correlation of ethanol elimination rates in vivo with liver alcohol dehydrogenase activities in fed, fasted and food-restricted rats

1979 • 105 citations

Double-ternary complex affinity chromatography: preparation of alcohol dehydrogenases

1976 • 102 citations

Metabolic alterations produced in the liver by chronic ethanol administration. Comparison between the effects produced by ethanol and by thyroid hormones

1973 • 101 citations

Acetaldehyde—Its Metabolism and Role in the Actions of Alcohol

1978 • 99 citations

Blood ethanol. A report of unusually high levels in a living patient

1973 • 90 citations

Vitamin B6 metabolism in chronic alcohol abuse The effect of ethanol oxidation on hepatic pyridoxal 5'-phosphate metabolism.

1975 • 86 citations

New molecular forms of human liver alcohol dehydrogenase: isolation and characterization of ADHIndianapolis.

1980 • 84 citations

Effects of castration and testosterone administration on rat liver alcohol dehydrogenase activity

1980 • 81 citations

Ethanol metabolism in Peromyscus genetically deficient in alcohol dehydrogenase

1980 • 77 citations

Blood Ethanol

1973 • 74 citations

ATYPICAL HUMAN LIVER ALCOHOL DEHYDROGENASE

1968 • 73 citations

Selective impairment of glycoprotein metabolism by ethanol and acetaldehyde in rat liver slices

1978 • 69 citations

Concentration Dependence of Ethanol Metabolism In Vivo in Rats and Man

1978 • 56 citations

Folate deficiency in alcoholism

1980 • 54 citations

Alcohol Distribution in the Vascular System: Concentration of Orally Administered Alcohol in Blood from Various Points in the Vascular System, and in Rebreathed Air, During Absorption

1964 • 51 citations

Enzymatic Pathways of Ethanol Metabolism

1979 • 46 citations

Nonethanol Substrates of Alcohol Dehydrogenase

1979 • 45 citations

Racial Comparisons of Alcohol Metabolism: Background, Problems, and Results

1978 • 45 citations

Increased hepatic production of alpha-amino-n-butyric acid after chronic alcohol consumption in rats and baboons

1980 • 39 citations

Hepatic microsomal ethanol-oxidizing system (MEOS): dissociation from reduced nicotinamide adenine dinucleotide phosphate oxidase and possible role of form I of cytochrome P-450.

1975 • 38 citations

Ethanol oxidation by isolated hepatocytes from fed and starved rats and from rats exposed to ethanol, phenobarbitone or 3-amino-triazole

1980 • 28 citations

Metabolism of ethanol and acetaldehyde by the isolated perfused rat brain.

1975 • 27 citations

Alcohol and aldehyde metabolizing systems—IV

1981 • 27 citations

Metabolism of ethanol and acetaldehyde by the isolated perfused rat brain

1975 • 23 citations

Rate-Determining Factors for Ethanol Metabolism in Vivo during Fasting

1980 • 21 citations

Effects of Ethanol on the Intermediary Metabolism of Liver and Brain

1979 • 21 citations

Chronopharmacokinetics of ethanol. III. Variation in rate of ethanolemia decay in human subjects.

1978 • 18 citations

The Presence of 2,3-Butanediol in the Blood of Chronic Alcoholics Admitted to an Alcohol Treatment Center

1980 • 16 citations

Factors Affecting the Distribution and Measurement of Ethanol in the Body

1979 • 11 citations

Quantitative correlation of ethanol elimination rates in vivo with liver alcohol dehydrogenase activities in fed, fasted and food-restricted rats

1979 • 10 citations

Effect of ethanol administration on free proline and glutamate in the intact rat liver

1980 • 8 citations

The Effects of Acetaldehyde and Disulfiram on Albumin Synthesis in the Isolated Perfused Rabbit Liver

1980 • 8 citations

Ethanol Metabolism in Perfused Liver and Isolated Hepatocytes with Associated Methodologies

1979 • 6 citations

Deleted Work

1955 • 0 citations