Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease: the GOLD science committee report 2019

Blood eosinophil counts, exacerbations, and response to the addition of inhaled fluticasone furoate to vilanterol in patients with chronic obstructive pulmonary disease: a secondary analysis of data from two parallel randomised controlled trials

2015 • 665 citations

Sputum eosinophilia and short-term response to prednisolone in chronic obstructive pulmonary disease: a randomised controlled trial

2000 • 570 citations

Blood Eosinophils to Direct Corticosteroid Treatment of Exacerbations of Chronic Obstructive Pulmonary Disease

2012 • 543 citations

Extrafine inhaled triple therapy versus dual bronchodilator therapy in chronic obstructive pulmonary disease (TRIBUTE): a double-blind, parallel group, randomised controlled trial

2018 • 505 citations

Blood eosinophil count and exacerbations in severe chronic obstructive pulmonary disease after withdrawal of inhaled corticosteroids: a post-hoc analysis of the WISDOM trial

2016 • 388 citations

Blood Eosinophils and Exacerbations in Chronic Obstructive Pulmonary Disease. The Copenhagen General Population Study

2015 • 374 citations

Predictors of exacerbation risk and response to budesonide in patients with chronic obstructive pulmonary disease: a post-hoc analysis of three randomised trials

2018 • 374 citations

Single inhaler extrafine triple therapy versus long-acting muscarinic antagonist therapy for chronic obstructive pulmonary disease (TRINITY): a double-blind, parallel group, randomised controlled trial

2017 • 372 citations

Sputum eosinophilia and the short term response to inhaled mometasone in chronic obstructive pulmonary disease

2005 • 358 citations

Effect of roflumilast on exacerbations in patients with severe chronic obstructive pulmonary disease uncontrolled by combination therapy (REACT): a multicentre randomised controlled trial

2015 • 335 citations

Blood eosinophils and inhaled corticosteroid/long-acting β-2 agonist efficacy in COPD

2015 • 293 citations

Association of sputum and blood eosinophil concentrations with clinical measures of COPD severity: an analysis of the SPIROMICS cohort

2017 • 249 citations

Current concepts in targeting chronic obstructive pulmonary disease pharmacotherapy: making progress towards personalised management

2015 • 219 citations

Comparison of induced sputum with bronchial wash, bronchoalveolar lavage and bronchial biopsies in COPD

2000 • 219 citations

Long-Term Triple Therapy De-escalation to Indacaterol/Glycopyrronium in Patients with Chronic Obstructive Pulmonary Disease (SUNSET): A Randomized, Double-Blind, Triple-Dummy Clinical Trial

2018 • 214 citations

Inhaled corticosteroids in COPD: friend or foe?

2018 • 195 citations

Blood eosinophil count thresholds and exacerbations in patients with chronic obstructive pulmonary disease

2018 • 180 citations

Precision medicine in airway diseases: moving to clinical practice

2017 • 169 citations

Tiotropium + olodaterol shows clinically meaningful improvements in quality of life

2015 • 169 citations

Blood eosinophil count and pneumonia risk in patients with chronic obstructive pulmonary disease: a patient-level meta-analysis

2016 • 167 citations

Tiotropium and olodaterol in the prevention of chronic obstructive pulmonary disease exacerbations (DYNAGITO): a double-blind, randomised, parallel-group, active-controlled trial

2018 • 166 citations

Triple-Therapie mit einem Inhalator

2017 • 162 citations

Dual bronchodilation with QVA149 reduces patient-reported dyspnoea in COPD: the BLAZE study

2013 • 154 citations

Blood Eosinophils and Response to Maintenance Chronic Obstructive Pulmonary Disease Treatment. Data from the FLAME Trial

2017 • 153 citations

Prevalence of persistent blood eosinophilia: relation to outcomes in patients with COPD

2017 • 150 citations

Eosinophils in COPD: just another biomarker?

2017 • 148 citations

Blood and sputum eosinophils in COPD; relationship with bacterial load

2017 • 114 citations

Induced sputum and other outcome measures in chronic obstructive pulmonary disease: safety and repeatability

2001 • 112 citations

Comparative effectiveness of LABA-ICS versus LAMA as initial treatment in COPD targeted by blood eosinophils: a population-based cohort study

2018 • 90 citations

Current Controversies in the Pharmacological Treatment of Chronic Obstructive Pulmonary Disease

2016 • 75 citations

Stability of Blood Eosinophil Count in Patients with COPD in the UK Clinical Practice Research Datalink

2017 • 60 citations

Demographic and Clinical Characteristics of COPD Patients at Different Blood Eosinophil Levels in the UK Clinical Practice Research Datalink

2018 • 39 citations

Repeatability of Inflammatory Parameters in Induced Sputum of COPD Patients

2007 • 33 citations

Distribution, temporal stability and association with all-cause mortality of the 2017 GOLD groups in the ECLIPSE cohort

2018 • 14 citations

Deleted Work

1955 • 0 citations

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