Precision medicine in airway diseases: moving to clinical practice

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2016 • 2,553 citations

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2012 • 2,168 citations

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2012 • 2,003 citations

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2002 • 1,726 citations

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2014 • 1,405 citations

Azithromycin for Prevention of Exacerbations of COPD

2011 • 1,110 citations

The exposome: from concept to utility

2012 • 1,099 citations

Personalized medicine: Time for one-person trials

2015 • 1,079 citations

Chronic Obstructive Pulmonary Disease Phenotypes

2010 • 976 citations

Precision Medicine — Personalized, Problematic, and Promising

2015 • 962 citations

Endotyping asthma: new insights into key pathogenic mechanisms in a complex, heterogeneous disease

2008 • 948 citations

Acute Exacerbations of Chronic Obstructive Pulmonary Disease

2011 • 938 citations

After asthma: redefining airways diseases

2017 • 882 citations

Clinical Control and Histopathologic Outcome of Asthma when Using Airway Hyperresponsiveness as an Additional Guide to Long-Term Treatment

1999 • 882 citations

Treatable traits: toward precision medicine of chronic airway diseases

2016 • 850 citations

Exploring the Effects of Omalizumab in Allergic Asthma

2013 • 811 citations

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2011 • 803 citations

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2017 • 780 citations

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2012 • 748 citations

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2015 • 738 citations

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary

2017 • 627 citations

Human disease classification in the postgenomic era: A complex systems approach to human pathobiology

2007 • 586 citations

Blood Eosinophils to Direct Corticosteroid Treatment of Exacerbations of Chronic Obstructive Pulmonary Disease

2012 • 543 citations

Blood eosinophil count and prospective annual asthma disease burden: a UK cohort study

2015 • 507 citations

Omalizumab in Severe Allergic Asthma Inadequately Controlled With Standard Therapy

2011 • 501 citations

A new perspective on concepts of asthma severity and control

2008 • 456 citations

Plasma interleukin-6 concentrations, metabolic dysfunction, and asthma severity: a cross-sectional analysis of two cohorts

2016 • 448 citations

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2015 • 448 citations

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2017 • 448 citations

Lung-resident eosinophils represent a distinct regulatory eosinophil subset

2016 • 441 citations

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Eosinophilic airway inflammation and exacerbations of COPD: a randomised controlled trial

2007 • 437 citations

Diagnosis and definition of severe refractory asthma: an international consensus statement from the Innovative Medicine Initiative (IMI)

2010 • 329 citations

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2011 • 316 citations

The Platform Trial

2015 • 295 citations

External validity of randomised controlled trials in asthma: to whom do the results of the trials apply?

2006 • 293 citations

The exposome: a new paradigm to study the impact of environment on health

2014 • 267 citations

Application of ’omics technologies to biomarker discovery in inflammatory lung diseases

2013 • 255 citations

Seven Questions for Personalized Medicine

2015 • 251 citations

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2017 • 244 citations

Outcomes and markers in the assessment of chronic obstructive pulmonary disease

2006 • 244 citations

Targeting the interleukin pathway in the treatment of asthma

2015 • 242 citations

Blood eosinophils as a marker of response to inhaled corticosteroids in COPD

2016 • 226 citations

Systems Biology: An Approach

2010 • 221 citations

The microbiome in respiratory medicine: current challenges and future perspectives

2017 • 212 citations

Importance of concomitant local and systemic eosinophilia in uncontrolled asthma

2014 • 189 citations

The path to personalised medicine in COPD

2014 • 184 citations

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2010 • 182 citations

Predictors of Chronic Obstructive Pulmonary Disease Exacerbation Reduction in Response to Daily Azithromycin Therapy

2014 • 172 citations

Assessment of airway neutrophils by sputum colour: correlation with airways inflammation

2001 • 151 citations

External validity of randomized controlled trials in COPD

2006 • 138 citations

Uncertainty in the Era of Precision Medicine

2016 • 134 citations

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2013 • 125 citations

Exhaled nitric oxide predicts lung function decline in difficult-to-treat asthma

2008 • 119 citations

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2009 • 114 citations

Use of predictive algorithms in-home monitoring of chronic obstructive pulmonary disease and asthma

2016 • 93 citations

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2016 • 90 citations

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2017 • 88 citations

Exhaled nitric oxide to predict corticosteroid responsiveness and reduce asthma exacerbation rates

2013 • 85 citations

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2010 • 79 citations

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2013 • 77 citations

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2016 • 72 citations

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2014 • 71 citations

The concept of control of COPD in clinical practice

2014 • 51 citations

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2011 • 49 citations

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2009 • 49 citations

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2014 • 47 citations

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2015 • 44 citations

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2015 • 44 citations

Acute Exacerbations of COPD: Identification of Biological Clusters and Their Biomarkers

2011 • 40 citations

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2016 • 38 citations

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2016 • 26 citations

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2016 • 23 citations

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2015 • 18 citations

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2016 • 17 citations