Binding of blood coagulation factor VIII and its light chain to phosphatidylserine/phosphatidylcholine bilayers as measured by ellipsometry

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

Molecular cloning of a cDNA encoding human antihaemophilic factor

1984 • 937 citations

Structure of human factor VIII

1984 • 898 citations

Surface-dependent reactions of the vitamin K-dependent enzyme complexes

1990 • 853 citations

[Changes under the influence of high pressure of certain properties of myosin, actomyosin and actin].

1960 • 499 citations

Blood coagulation factors V and VIII: structural and functional similarities and their relationship to hemorrhagic and thrombotic disorders

1988 • 405 citations

The adsorption of prothrombin to phosphatidylserine multilayers quantitated by ellipsometry.

1983 • 383 citations

Platelet-derived microparticles express high affinity receptors for factor VIII.

1991 • 277 citations

Sulfation of Tyr1680 of human blood coagulation factor VIII is essential for the interaction of factor VIII with von Willebrand factor.

1991 • 275 citations

Inactivation of human factor VIII by activated protein C. Cofactor activity of protein S and protective effect of von Willebrand factor.

1988 • 244 citations

A Factor VIII Neutralizing Monoclonal Antibody and a Human Inhibitor Alloantibody Recognizing Epitopes in the C2 Domain Inhibit Factor VIII Binding to von Willebrand Factor and to Phosphatidylserine

1993 • 199 citations

Synthetic factor VIII peptides with amino acid sequences contained within the C2 domain of factor VIII inhibit factor VIII binding to phosphatidylserine

1990 • 198 citations

Differential scanning calorimetry and 31P NMR studies on sonicated and unsonicated phosphatidylcholine liposomes

1975 • 196 citations

A role for the C2 domain of factor VIII in binding to von Willebrand factor

1994 • 192 citations

Molecular basis of factor VIII inhibition by human antibodies. Antibodies that bind to the factor VIII light chain prevent the interaction of factor VIII with phospholipid.

1989 • 183 citations

Identification of a binding site for blood coagulation factor IXa on the light chain of human factor VIII.

1994 • 175 citations

Binding of human factor VIII to phospholipid vesicles.

1990 • 142 citations

Isolation and characterization of human factor VIII: molecular forms in commercial factor VIII concentrate, cryoprecipitate, and plasma.

1986 • 140 citations

An immunogenic region within residues Val1670-Glu1684 of the factor VIII light chain induces antibodies which inhibit binding of factor VIII to von Willebrand factor.

1988 • 136 citations

von Willebrand factor mediates protection of factor VIII from activated protein C-catalyzed inactivation

1991 • 125 citations

Deletion analysis of recombinant human factor V. Evidence for a phosphatidylserine binding site in the second C-type domain.

1992 • 115 citations

The binding of 35S-labeled recombinant factor VIII to activated and unactivated human platelets.

1988 • 107 citations

Specific membrane binding of factor VIII is mediated by O-phospho-L-serine, a moiety of phosphatidylserine

1993 • 94 citations

Characterization of two forms of human factor Va with different cofactor activities.

1993 • 93 citations

Specificity of phosphatidylserine-containing membrane binding sites for factor VIII. Studies with model membranes supported by glass microspheres (lipospheres).

1992 • 88 citations

Characterization of recombinant human factor VIII.

1987 • 76 citations

Localization of functionally important epitopes within the second C-type domain of coagulation factor V using recombinant chimeras.

1994 • 67 citations

Inhibition of human coagulation factor VIII by monoclonal antibodies. Mapping of functional epitopes with the use of recombinant factor VIII fragments

1989 • 65 citations

The adsorption of prothrombin to phospholipid monolayers quantitated by ellipsometry.

1984 • 56 citations

Membrane binding kinetics of factor VIII indicate a complex binding process.

1993 • 55 citations

Intersubunit Fluorescence Energy Transfer in Human Factor VIII

1989 • 47 citations

The interaction of rDNA factor VIII, factor VIIIdes-797-1562 and factor VIIIdes-797-1562-derived peptides with phospholipid

1987 • 39 citations

Electron microscopy of human factor V and factor VIII: correlation of morphology with domain structure and localization of factor V activation fragments.

1990 • 37 citations

Structural model of porcine factor VIII and factor VIIIa molecules based on scanning transmission electron microscope (STEM) images and STEM mass analysis.

1990 • 26 citations

Application of sepharose-linked monoclonal antibodies for the immunoradiometric measurement of factor VIII-procoagulant antigen

1984 • 18 citations

Monitoring of unbound protein in vesicle suspensions with off-null ellipsometry

1993 • 15 citations