Exhaled nitric oxide to predict corticosteroid responsiveness and reduce asthma exacerbation rates

An Official ATS Clinical Practice Guideline: Interpretation of Exhaled Nitric Oxide Levels (F<scp>e</scp>_NO) for Clinical Applications

2011 • 2,199 citations

Identification of Asthma Phenotypes Using Cluster Analysis in the Severe Asthma Research Program

2009 • 1,922 citations

Mepolizumab and Exacerbations of Refractory Eosinophilic Asthma

2009 • 1,797 citations

Lebrikizumab Treatment in Adults with Asthma

2011 • 1,482 citations

Asthma endotypes: A new approach to classification of disease entities within the asthma syndrome

2011 • 1,077 citations

Trends in asthma prevalence, health care use, and mortality in the United States, 2001-2010.

2012 • 1,013 citations

Use of Exhaled Nitric Oxide Measurements to Guide Treatment in Chronic Asthma

2005 • 965 citations

How much asthma is really attributable to atopy?

1999 • 647 citations

Non-eosinophilic asthma: importance and possible mechanisms

2002 • 644 citations

Costs of asthma in the United States: 2002-2007

2011 • 591 citations

Exhaled nitric oxide measurements: clinical application and interpretation

2006 • 510 citations

Inhaled corticosteroids for stable chronic obstructive pulmonary disease

2012 • 503 citations

Diagnosing Asthma

2003 • 472 citations

A Large Subgroup of Mild-to-Moderate Asthma Is Persistently Noneosinophilic

2012 • 462 citations

Management of asthma based on exhaled nitric oxide in addition to guideline-based treatment for inner-city adolescents and young adults: a randomised controlled trial

2008 • 455 citations

The Predictive Value of Exhaled Nitric Oxide Measurements in Assessing Changes in Asthma Control

2001 • 441 citations

Inhaled Corticosteroids for Asthma Therapy

2000 • 422 citations

The mechanisms, diagnosis, and management of severe asthma in adults

2006 • 398 citations

Asthma in older adults

2010 • 366 citations

Exhaled Nitric Oxide

2005 • 365 citations

Titrating Steroids on Exhaled Nitric Oxide in Children with Asthma

2005 • 360 citations

Exhaled nitric oxide measurements

2006 • 348 citations

The Use of Exhaled Nitric Oxide to Guide Asthma Management

2007 • 345 citations

The Proportional Venn Diagram of Obstructive Lung Disease*

2003 • 326 citations

Predictive Markers of Asthma Exacerbation during Stepwise Dose Reduction of Inhaled Corticosteroids

2001 • 324 citations

A systematic review and meta-analysis: tailoring asthma treatment on eosinophilic markers (exhaled nitric oxide or sputum eosinophils)

2010 • 323 citations

Clinical Use of Noninvasive Measurements of Airway Inflammation in Steroid Reduction in Children

2005 • 322 citations

Management of asthma in pregnancy guided by measurement of fraction of exhaled nitric oxide: a double-blind, randomised controlled trial

2011 • 316 citations

The use of exhaled nitric oxide concentration to identify eosinophilic airway inflammation: an observational study in adults with asthma

2005 • 309 citations

Effects of steroid therapy on inflammatory cell subtypes in asthma

2009 • 297 citations

Asthma outcomes: Exacerbations

2012 • 289 citations

Daily Telemonitoring of Exhaled Nitric Oxide and Symptoms in the Treatment of Childhood Asthma

2008 • 219 citations

The Asthma-COPD Overlap Syndrome: A Common Clinical Problem in the Elderly

2011 • 205 citations

Comparison of Physician-, Biomarker-, and Symptom-Based Strategies for Adjustment of Inhaled Corticosteroid Therapy in Adults With Asthma

2012 • 186 citations

Sputum eosinophil counts predict asthma control after discontinuation of inhaled corticosteroids

2005 • 186 citations

Tailored interventions based on exhaled nitric oxide versus clinical symptoms for asthma in children and adults

2009 • 180 citations

Role of Spirometry and Exhaled Nitric Oxide To Predict Exacerbations in Treated Asthmatics

2006 • 163 citations

Exhaled Nitric Oxide as a Noninvasive Assessment of Chronic Cough

1999 • 163 citations

Changes of exhaled nitric oxide during steroid treatment of childhood asthma

2002 • 160 citations

Reported Pneumonia in Patients With COPD

2010 • 158 citations

Basic aspects of exhaled nitric oxide

2010 • 144 citations

Emerging Roles of T Helper Subsets in the Pathogenesis of Asthma

2010 • 122 citations

The Use of Exhaled Nitric Oxide in the Diagnosis of Asthma in School Children

2009 • 96 citations

Normal Values and Thresholds for the Clinical Interpretation of Exhaled Nitric Oxide Levels in the US General Population

2012 • 78 citations

Predicting Corticosteroid Response in Chronic Obstructive Pulmonary Disease Using Exhaled Nitric Oxide

2009 • 75 citations

Exhaled nitric oxide reflects asthma severity and asthma control

2004 • 69 citations

Exhaled nitric oxide, systemic inflammation, and the spirometric response to inhaled fluticasone propionate in severe chronic obstructive pulmonary disease: A prospective study

2008 • 68 citations

The influence of inhaled corticosteroids on exhaled nitric oxide in stable chronic obstructive pulmonary disease

2005 • 68 citations

Diagnostic Classification of Persistent Rhinitis and Its Relationship to Exhaled Nitric Oxide and Asthma

2007 • 68 citations

Airway hyperresponsiveness to mannitol and methacholine and exhaled nitric oxide: A random-sample population study

2010 • 67 citations

Comparison of exhaled nitric oxide measurement with conventional tests in steroid-naive asthma patients.

2006 • 67 citations

Exhaled Nitric Oxide Measurement Is Useful for the Exclusion of Nonasthmatic Eosinophilic Bronchitis in Patients With Chronic Cough

2008 • 66 citations

Relationship between exhaled nitric oxide and treatment response in COPD patients with exacerbations

2010 • 65 citations

Use of Exhaled Nitric Oxide in Predicting Response to Inhaled Corticosteroids for Chronic Cough

2007 • 62 citations

Exhaled nitric oxide predicts control in patients with difficult-to-treat asthma

2009 • 60 citations

Diagnosing asthma in general practice with portable exhaled nitric oxide measurement – results of a prospective diagnostic study

2009 • 54 citations

Determinants of Exhaled Nitric Oxide in Chronic Rhinosinusitis

2009 • 53 citations

(Correcting) misdiagnoses of asthma: a cost effectiveness analysis

2011 • 51 citations

Long-term therapy in COPD: any evidence of adverse effect on bone?

2009 • 49 citations

Exhaled Nitric Oxide in Evaluation of Young Adults with Chronic Cough

2009 • 45 citations

Clinical application of a simple questionnaire for the differentiation of asthma and chronic obstructive pulmonary disease

2004 • 44 citations

Management of Asthma in Pregnancy Guided by Measurement of Fraction of Exhaled Nitric Oxide

2012 • 38 citations

Asthma symptoms and medication in the PIAMA birth cohort: Evidence for under and overtreatment

2011 • 34 citations

Improvement of Airflow Limitation by Fluticasone Propionate/Salmeterol in Chronic Obstructive Pulmonary Disease: What is the Specific Marker?

2011 • 34 citations

Utility of nitric oxide for the diagnosis of asthma in an allergy clinic population

2011 • 33 citations

Advances in the clinical applications of exhaled nitric oxide measurements

2012 • 33 citations

Is FENO50 useful diagnostic tool in suspected asthma?

2012 • 28 citations

Usefulness of Exhaled Nitric Oxide to Guide Risk Stratification for Bronchiolitis Obliterans Syndrome After Lung Transplantation

2010 • 26 citations

Comparison of the Asthma in America and Asthma Insight and Management surveys: Did asthma burden and care improve in the United States between 1998 and 2009?

2012 • 21 citations

National Jewish Health

2011 • 14 citations

Spirometric Maneuvers and Inhaled Salbutamol Do Not Affect Exhaled Nitric Oxide Measurements among Patients with Allergic Asthma

2011 • 10 citations