Liver fluke infection and cholangiocarcinoma: a review

A review of human carcinogens—Part B: biological agents

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REDOX REGULATION OF CELLULAR ACTIVATION

1997 • 1,121 citations

Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA

2000 • 931 citations

MUTAGENESIS BY APURINIC/APYRIMIDINIC SITES

1986 • 884 citations

Food-Borne Trematodiases

2009 • 583 citations

Thioredoxin and thioredoxin reductase: Current research with special reference to human disease

2010 • 531 citations

The tumorigenic liver fluke Opisthorchis viverrini – multiple pathways to cancer

2012 • 422 citations

The non-marine aquatic Mollusca of Thailand

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Lipid peroxidation-induced DNA damage in cancer-prone inflammatory diseases: A review of published adduct types and levels in humans

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Formation of 8‐nitroguanine in DNA treated with peroxynitrite in vitro and its rapid removal from DNA by depurination

1995 • 343 citations

Food-Borne Trematodiases in Southeast Asia

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Liver fluke-associated cholangiocarcinoma

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Thioredoxin signaling as a target for cancer therapy

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Clonorchiasis

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Opisthorchiasis control in Thailand

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Cloning of a novel human Rac1b splice variant with increased expression in colorectal tumors

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Biological and clinical significance of KRAS mutations in lung cancer: an oncogenic driver that contrasts with EGFR mutation

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Roles of liver fluke infection as risk factor for cholangiocarcinoma

2014 • 201 citations

Grb2 signaling in cell motility and cancer

2008 • 200 citations

A Granulin-Like Growth Factor Secreted by the Carcinogenic Liver Fluke, Opisthorchis viverrini, Promotes Proliferation of Host Cells

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The current pathobiology and chemotherapy of clonorchiasis

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Pathobiology of opisthorchiasis: an update

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Oxidative and nitrative DNA damage: Key events in opisthorchiasis-induced carcinogenesis

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Opisthorchis viverrini: The carcinogenic human liver fluke

2008 • 155 citations

Advanced periductal fibrosis from infection with the carcinogenic human liver fluke Opisthorchis viverrini correlates with elevated levels of interleukin-6

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Liver Changes in Hamsters Infected with a Liver Fluke of Man, Opisthorchis Viverrini *

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Unlocking the Transcriptomes of Two Carcinogenic Parasites, Clonorchis sinensis and Opisthorchis viverrini

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The dynamic biliary epithelia: Molecules, pathways, and disease

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The secreted and surface proteomes of the adult stage of the carcinogenic human liver fluke Opisthorchis viverrini

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Infection with the carcinogenic liver fluke Opisthorchis viverrini modifies intestinal and biliary microbiome

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Mechanism of the Aldolase Reaction

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Elucidating the transcriptome of Fasciola hepatica — A key to fundamental and biotechnological discoveries for a neglected parasite

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AIP1/DAB2IP, a Novel Member of the Ras-GAP Family, Transduces TRAF2-induced ASK1-JNK Activation

2004 • 124 citations

Helminths in human carcinogenesis

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8-Nitroguanine formation in the liver of hamsters infected with Opisthorchis viverrini

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Aldolase Is Essential for Energy Production and Bridging Adhesin-Actin Cytoskeletal Interactions during Parasite Invasion of Host Cells

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Schistosoma bovis: Plasminogen binding in adults and the identification of plasminogen-binding proteins from the worm tegument

2006 • 105 citations

Elevated Plasma IL-6 Associates with Increased Risk of Advanced Fibrosis and Cholangiocarcinoma in Individuals Infected by Opisthorchis viverrini

2012 • 103 citations

Gene discovery for the carcinogenic human liver fluke, Opisthorchis viverrini

2007 • 99 citations

The Carcinogenic Liver Fluke, Clonorchis sinensis: New Assembly, Reannotation and Analysis of the Genome and Characterization of Tissue Transcriptomes

2013 • 94 citations

Aberrant expression of Cks1 and Cks2 contributes to prostate tumorigenesis by promoting proliferation and inhibiting programmed cell death

2008 • 90 citations

iNOS‐dependent DNA damage via NF‐κB expression in hamsters infected with Opisthorchis viverrini and its suppression by the antihelminthic drug praziquantel

2006 • 89 citations

Involvement of MMP‐9 in peribiliary fibrosis and cholangiocarcinogenesis via Rac1‐dependent DNA damage in a hamster model

2010 • 87 citations

Time profiles of the expression of metalloproteinases, tissue inhibitors of metalloproteases, cytokines and collagens in hamsters infected with Opisthorchis viverrini with special reference to peribiliary fibrosis and liver injury

2009 • 82 citations

Increased cell proliferation of mouse fibroblast NIH-3T3 in vitro induced by excretory/secretory product(s) from Opisthorchis viverrini

2004 • 80 citations

Opisthorchis viverrini excretory/secretory products induce toll-like receptor 4 upregulation and production of interleukin 6 and 8 in cholangiocyte

2010 • 78 citations

Immunology and molecular biology of Opisthorchis viverrini infection

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Association of liver fluke (Opisthorchis viverrini) infestation with increased expression of cytochrome p450 and carcinogen metabolism in male hamster liver^1,2

1994 • 76 citations

Akt and 14-3-3η regulate Miz1 to control cell-cycle arrest after DNA damage

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Induction of cytochrome P450 2A6 expression in humans by the carcinogenic parasite infection, opisthorchiasis viverrini.

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Effect of Clonorchis sinensis infection and dimethylnitrosamine administration on the induction of cholangiocarcinoma in Syrian golden hamsters

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Characterization of Humoral Immune Response in the Serum and Bile of Patients with Opisthorchiasis and Its Application in Immunodiagnosis

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A review of the control of clonorchiasis sinensis and Taenia solium taeniasis/cysticercosis in China

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Human pathology of Opisthorchis viverrini infection: a comparison of adults and children.

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The Carcinogenic Liver Fluke Opisthorchis viverrini is a Reservoir for Species of Helicobacter

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Sequences and gene organization of the mitochondrial genomes of the liver flukes Opisthorchis viverrini and Clonorchis sinensis (Trematoda)

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Schistosome and liver fluke derived catechol-estrogens and helminth associated cancers

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Clonorchis and Clonorchiasis

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Proliferative effects of excretory/secretory products from Clonorchis sinensis on the human epithelial cell line HEK293 via regulation of the transcription factor E2F1

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Dissection of theAscarisSperm Motility Machinery Identifies Key Proteins Involved in Major Sperm Protein-based Amoeboid Locomotion

2003 • 52 citations

Urinary microRNA-192 and microRNA-21 as potential indicators for liver fluke-associated cholangiocarcinoma risk group

2015 • 51 citations

Free radicals enzymatically triggered by Clonorchis sinensis excretory–secretory products cause NF-κB-mediated inflammation in human cholangiocarcinoma cells

2011 • 51 citations

Excretory/secretory products of the carcinogenic liver fluke are endocytosed by human cholangiocytes and drive cell proliferation and IL6 production

2015 • 48 citations

Opisthorchis viverrini antigen induces the expression of Toll-like receptor 2 in macrophage RAW cell line

2005 • 47 citations

The systematics and population genetics of Opisthorchis viverrini sensu lato: Implications in parasite epidemiology and bile duct cancer

2011 • 45 citations

Differential gene expression profiling in human cholangiocarcinoma cells treated with Clonorchis sinensis excretory-secretory products

2008 • 42 citations

BRAFV600E Efficient Transformation and Induction of Microsatellite Instability Versus KRASG12V Induction of Senescence Markers in Human Colon Cancer Cells

2009 • 42 citations

Expressed sequence tag analysis of adult Clonorchis sinensis, the Chinese liver fluke

2006 • 41 citations

Gene expression profiling defined pathways correlated with fibroblast cell proliferation induced by Opisthorchis viverrini excretory/secretory product

2006 • 39 citations

Apoptosis of cholangiocytes modulated by thioredoxin of carcinogenic liver fluke

2015 • 39 citations

Induction of cancer-related microRNA expression profiling using excretory-secretory products of Clonorchis sinensis

2014 • 38 citations

Anopheles Gambiae PRS1 Modulates Plasmodium Development at Both Midgut and Salivary Gland Steps

2010 • 36 citations

Expression of Toll-like receptor (TLR) 2 and TLR4 in the livers of mice infected by Clonorchis sinensis

2015 • 34 citations

REMARKS ON THE ANATOMY AND PATHOLOGICAL RELATIONS OF A NEW SPECIES OF LIVER-FLUKE.

1875 • 33 citations

Notes of the Occurrence of Parasites Presumably Rare in Man

1915 • 33 citations

RNA interference targeting cathepsin B of the carcinogenic liver fluke, Opisthorchis viverrini

2011 • 33 citations

Identification of different isoforms of 14-3-3 protein family in human dermal and epidermal layers

2008 • 33 citations

Oxidative stress-mediated mouse liver lesions caused by Clonorchis sinensis infection

2015 • 32 citations

Upregulation of 14‐3‐3 eta in chronic liver fluke infection is a potential diagnostic marker of cholangiocarcinoma

2015 • 30 citations

Suppression of Ov-grn-1 encoding granulin of Opisthorchis viverrini inhibits proliferation of biliary epithelial cells

2014 • 30 citations

Gene expression profile of Clonorchis sinensis metacercariae

2007 • 29 citations

Cancer biomarker discovery for cholangiocarcinoma: the high‐throughput approaches

2014 • 29 citations

Theoretical Study of the Unusual Protonation Properties of the Active Site Cysteines in Thioredoxin

2006 • 27 citations

Progress on the transcriptomics of carcinogenic liver flukes of humans—Unique biological and biotechnological prospects

2010 • 27 citations

Comparative cytogenetics of opisthorchid species (Trematoda, Opisthorchiidae)

2011 • 25 citations

Structure of MFP2 and its Function in Enhancing MSP Polymerization in Ascaris Sperm Amoeboid Motility

2005 • 24 citations

Clonorchis sinensis ferritin heavy chain triggers free radicals and mediates inflammation signaling in human hepatic stellate cells

2014 • 23 citations

Suppression of trophoblast cell surface antigen 2 enhances proliferation and migration in liver fluke-associated cholangiocarcinoma

2015 • 22 citations

Helicobacter Species are Possible Risk Factors of Cholangiocarcinoma

2016 • 21 citations

Increase in L-type amino acid transporter 1 expression during cholangiocarcinogenesis caused by liver fluke infection and its prognostic significance

2015 • 20 citations

Proteomic characterization of the internalization of Opisthorchis viverrini excretory/secretory products in human cells

2016 • 20 citations

Chromosomes and karyotype analysis of a liver fluke, Opisthorchis viverrini, by scanning electron microscopy

2012 • 17 citations

Similarity of a 16.5 kDa tegumental protein of the human liver fluke Opisthorchis viverrini to nematode cytoplasmic motility protein

2016 • 11 citations

Association of CYP39A1, RUNX2 and Oxidized Alpha-1 Antitrypsin Expression in Relation to Cholangiocarcinoma Progression

2015 • 10 citations

Hepatic cytochrome P450 2A6 and 2E1 status in peri-tumor tissues of patients with Opisthorchis viverrini-associated cholangiocarcinoma

2011 • 9 citations

Characterization and localization of Opisthorchis viverrini fructose-1,6-bisphosphate aldolase

2016 • 8 citations

Genomics of worms, with an emphasis on Opisthorchis viverrini — opportunities for fundamental discovery and biomedical outcomes

2016 • 7 citations

Therapeutic approach to the malignant tumors of the biliary tract.

2010 • 4 citations

[Serum level of intercellular adhesion molecule-1 in patients with clonorchiasis and its impact on liver function].

2013 • 3 citations