Differential expression of extracellular matrix remodeling genes in a murine model of bleomycin-induced pulmonary fibrosis.

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Matrix metalloproteinases and their inhibitors in connective tissue remodeling

1991 • 3,309 citations

Matrix Metalloproteinases: A Review

1993 • 2,998 citations

Metalloproteinases and their inhibitors in matrix remodeling

1990 • 1,627 citations

Requirement for Macrophage Elastase for Cigarette Smoke-Induced Emphysema in Mice

1997 • 1,463 citations

Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor.

1987 • 1,243 citations

Three different fibronectin mRNAs arise by alternative splicing within the coding region

1983 • 713 citations

Independent Regulation of Collagenase, 72-kDa Progelatinase, and Metalloendoproteinase Inhibitor Expression in Human Fibroblasts by Transforming Growth Factor-β

1989 • 649 citations

Molecular Cloning and Characterization of Human Tissue Inhibitor of Metalloproteinase 4

1996 • 547 citations

Metalloelastase is required for macrophage-mediated proteolysis and matrix invasion in mice.

1996 • 496 citations

Tissue inhibitor of metalloproteinases-3 (TIMP-3) is an extracellular matrix-associated protein with a distinctive pattern of expression in mouse cells and tissues.

1994 • 485 citations

Cloning and characterization of a unique elastolytic metalloproteinase produced by human alveolar macrophages.

1993 • 479 citations

The Family of Matrix Metalloproteinases^a

1994 • 437 citations

Mechanisms of bleomycin-induced lung damage

1991 • 356 citations

Expression of tissue inhibitor of metalloproteinases 1 and 2 is increased in fibrotic human liver

1996 • 349 citations

Lung Cytokine Production in Bleomycin-Induced Pulmonary Fibrosis

1992 • 321 citations

Hydrolysis of a Broad Spectrum of Extracellular Matrix Proteins by Human Macrophage Elastase

1997 • 313 citations

Effect of steroids on CSF matrix metalloproteinases in multiple sclerosis

1996 • 278 citations

Cytokine regulation of matrix metalloproteinase activity and its regulatory dysfunction in disease.

1995 • 273 citations

Tissue inhibitor of metalloproteinases (TIMP, aka EPA): Structure, control of expression and biological functions

1993 • 270 citations

The mRNA coding for the secreted protease transin is expressed more abundantly in malignant than in benign tumors.

1986 • 260 citations

Mouse macrophage elastase. Purification and characterization as a metalloproteinase

1981 • 260 citations

Differential expression of matrix-metalloproteinase-1 and -2 genes in normal and fibrotic human liver.

1994 • 253 citations

Immunohistochemical study of metalloproteinases and their tissue inhibitors in the lungs of patients with diffuse alveolar damage and idiopathic pulmonary fibrosis.

1996 • 234 citations

Molecular cloning, chromosomal localization, and bacterial expression of a murine macrophage metalloelastase.

1992 • 197 citations

Murine tissue inhibitor of metalloproteinases—4 (Timp—4): cDNA isolation and expression in adult mouse tissues¹

1997 • 192 citations

Molecular cloning of murine 72-kDa type IV collagenase and its expression during mouse development.

1992 • 189 citations

The Role of Strain Variation in Murine Bleomycin-lnduced Pulmonary Fibrosis^1,2

1983 • 183 citations

Specific hybridization probes for mouse type I, II, III and IX collagen mRNAs

1991 • 165 citations

Human Macrophage Metalloelastase. GENOMIC ORGANIZATION, CHROMOSOMAL LOCATION, GENE LINKAGE, AND TISSUE-SPECIFIC EXPRESSION

1995 • 156 citations

A growth-responsive gene (16C8) in normal mouse fibroblasts homologous to a human collagenase inhibitor with erythroid-potentiating activity: evidence for inducible and constitutive transcripts

1986 • 155 citations

Matrix metalloproteases and lung disease.

1994 • 151 citations

Induction of 103-kDa gelatinase/type IV collagenase by acidic culture conditions in mouse metastatic melanoma cell lines.

1992 • 147 citations

Regulation of the expression of tissue inhibitor of metalloproteinases and collagenase by retinoids and glucocorticoids in human fibroblasts.

1987 • 146 citations

The roles of tissue inhibitors of metalloproteinases in tissue remodelling and cell growth.

1996 • 142 citations

High dose continuous infusion of bleomycin in mice: a new model for drug-induced pulmonary fibrosis.

1987 • 141 citations

New perspectives on basic mechanisms in lung disease. 6. Proteinase imbalance: its role in lung disease.

1993 • 141 citations

Gene encoding a novel murine tissue inhibitor of metalloproteinases (TIMP), TIMP‐3, is expressed in developing mouse epithelia, cartilage, and muscle, and is located on mouse chromosome 10

1994 • 135 citations

Profiles of steady state levels of messenger RNAs coding for type I procollagen, elastin, and fibronectin in hamster lungs undergoing bleomycin-induced interstitial pulmonary fibrosis.

1985 • 131 citations

Cloning and sequencing of mouse collagenase cDNA Divergence of mouse and rat collagenases from the other mammalian collagenases

1992 • 120 citations

Transforming growth factor beta 1 and cAMP inhibit transcription of epidermal growth factor- and oncogene-induced transin RNA.

1988 • 107 citations

Differential regulation of TIMP-1 and TIMP-2 mRNA expression in normal and Ha-ras-transformed murine fibroblasts

1992 • 96 citations

Temporal expression of tissue inhibitors of metalloproteinases in mouse reproductive tissues during gestation

1993 • 89 citations

The role of cytokines in human lung fibrosis.

1996 • 77 citations

Production of Collagenase and Tissue inhibitor of Metalloproteinases by Fibroblasts Derived from Normal and Fibrotic Human Lungs

1992 • 73 citations

Susceptibility to experimental interstitial lung disease is modified by immune- and non-immune-related genes.

1987 • 63 citations

In situ hybridization analysis of rat lung alpha 1(I) and alpha 2(I) collagen gene expression in pulmonary fibrosis induced by endotracheal bleomycin injection.

1994 • 55 citations

Enhanced type III collagen gene expression during bleomycin induced lung fibrosis.

1993 • 40 citations

Cloning and expression of the cDNA encoding mouse neutrophil gelatinase: demonstration of coordinate secondary granule protein gene expression during terminal neutrophil maturation

1993 • 40 citations

Increased type I procollagen mRNA transcripts in the lungs of mice during the development of bleomycin-induced fibrosis

1994 • 23 citations

Gene Expression of Metalloproteinases and Their Inhibitor in Renal Tissue of New Zealand Black/White F1 Mice

1993 • 22 citations

Alveolar macrophage secretion of a 92-kDa gelatinase in response to bleomycin

1993 • 11 citations