Temporal expression of tissue inhibitors of metalloproteinases in mouse reproductive tissues during gestation

Matrix metalloproteinases and their inhibitors in connective tissue remodeling

1991 • 3,309 citations

Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation

1991 • 2,774 citations

Metalloproteinases and their inhibitors in matrix remodeling

1990 • 1,627 citations

A Method for Isolation of Intact, Translationally Active Ribonucleic Acid

1983 • 1,469 citations

Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor.

1987 • 1,243 citations

SV40-transformed Human Lung Fibroblasts Secrete a 92-kDa Type IV Collagenase Which Is Identical to That Secreted by Normal Human Macrophages

1989 • 1,122 citations

H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen.

1988 • 1,050 citations

Tissue Inhibitor of Metalloproteinase (TIMP-2)

1989 • 899 citations

Tumor invasion through the human amniotic membrane: Requirement for a proteinase cascade

1986 • 764 citations

Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity

1985 • 702 citations

Independent Regulation of Collagenase, 72-kDa Progelatinase, and Metalloendoproteinase Inhibitor Expression in Human Fibroblasts by Transforming Growth Factor-β

1989 • 649 citations

Human 72-kilodalton type IV collagenase forms a complex with a tissue inhibitor of metalloproteases designated TIMP-2.

1989 • 594 citations

Antisense RNA-Induced Reduction in Murine TIMP Levels Confers Oncogenicity on Swiss 3T3 Cells

1989 • 459 citations

TGF-β1 inhibition of transin/stromelysin gene expression is mediated through a fos binding sequence

1990 • 444 citations

Inhibition of invasion and metastasis in cells transfected with an inhibitor of metalloproteinases.

1992 • 429 citations

Tissue inhibitor of metalloproteinases-2 (TIMP-2) mRNA expression in tumor cell lines and human tumor tissues.

1990 • 428 citations

Tumor Cell Invasion Inhibited by TIMP-2

1991 • 324 citations

Inhibition by human recombinant tissue inhibitor of metalloproteinases of human amnion invasion and lung colonization by murine B16-F10 melanoma cells.

1988 • 312 citations

Genes for extracellular-matrix-degrading metalloproteinases and their inhibitor, TIMP, are expressed during early mammalian development.

1989 • 284 citations

Mechanisms of trophoblast invasiveness and their control: the role of proteases and protease inhibitors

1990 • 267 citations

The mRNA coding for the secreted protease transin is expressed more abundantly in malignant than in benign tumors.

1986 • 260 citations

Human skin fibroblast collagenase inhibitor. Comparative studies in human connective tissues, serum, and amniotic fluid.

1983 • 231 citations

Metalloproteinases mediate extracellular matrix degradation by cells from mouse blastocyst outgrowths

1992 • 221 citations

Normal nonmetastatic human trophoblast cells share in vitro invasive properties of malignant cells

1988 • 202 citations

cDNA cloning and expression of a metalloproteinase inhibitor related to tissue inhibitor of metalloproteinases.

1990 • 202 citations

An inhibitor of collagenase from human amniotic fluid. Purification, characterization and action on metalloproteinases

1981 • 171 citations

Optimized Hybridization of DNA Blotted and Fixed to Nitrocellulose and Nylon Membranes

1987 • 159 citations

A growth-responsive gene (16C8) in normal mouse fibroblasts homologous to a human collagenase inhibitor with erythroid-potentiating activity: evidence for inducible and constitutive transcripts

1986 • 155 citations

Mechanism of mammalian ovulation

1989 • 150 citations

Regulation of the expression of tissue inhibitor of metalloproteinases and collagenase by retinoids and glucocorticoids in human fibroblasts.

1987 • 146 citations

Suppression of Invasion by Inducible Expression of Tissue Inhibitor of Metalloproteinase-1 (TIMP-1) in B 16-F10 Melanoma Cells

1992 • 137 citations

Hormonal regulation of collagenolysis in uterine cervical fibroblasts. Modulation of synthesis of procollagenase, prostromelysin and tissue inhibitor of metalloproteinases (TIMP) by progesterone and oestradiol-17 β

1991 • 135 citations

Involvement of AP1 and PEA3 binding sites in the regulation of murine tissue inhibitor of metalloproteinases-1 (TIMP-1) transcription

1992 • 122 citations

Studies of the mechanism(s) of mammalian ovulation

1987 • 114 citations

Developmental expression of tissue inhibitor of metalloproteinase (TIMP) RNA

1989 • 114 citations

Targeted disruption of the tissue inhibitor of metalloproteinases gene increases the invasive behavior of primitive mesenchymal cells derived from embryonic stem cells in vitro.

1992 • 109 citations

Differential regulation of TIMP-1 and TIMP-2 mRNA expression in normal and Ha-ras-transformed murine fibroblasts

1992 • 96 citations

Hormonal Regulation of Matrix Metalloproteinase Inhibitors in Rat Granulosa Cells and Ovaries*

1991 • 91 citations

Developmental expression of the endogenous TIMP gene and a TIMP-lacZ fusion gene in transgenic mice.

1990 • 86 citations

Monocyte procollagenase and tissue inhibitor of metalloproteinases. Identification, characterization, and regulation of secretion.

1987 • 79 citations

Up-regulation of TIMP-1 expression in B16-F10 melanoma cells suppresses their metastatic ability in chick embryo

1992 • 76 citations

A study of mitochondrial and nuclear transcription with cloned cDNA probes

1985 • 73 citations

Regulated temporal and spatial expression of the calcium‐binding proteins calcyclin and opn (osteopontin) in mouse tissues during pregnancy

1992 • 56 citations

Localization of Preovulatory Expression of Plasminogen Activator Inhibitor Type-1 and Tissue Inhibitor of Metalloproteinase Type-1 mRNAs in the Rat Ovary1

1992 • 49 citations

Biochemical Evidence of Collagenase-Mediated Collagenolysis as a Mechanism of Cervical Dilatation at Parturition in the Guinea Pig1

1991 • 43 citations

Presence of transcription regulatory elements within an intron of the virus-inducible murine TIMP gene.

1988 • 42 citations

Differentiation of a human leukemia cell line and expression of collagenase inhibitor.

1985 • 36 citations

Collagen concentrations in dissected tissue compartments of rat uterus on Days 6, 7 and 8 of pregnancy

1992 • 21 citations

Textbook of Rheumatology. Ed. 3.

1989 • 15 citations

Normal Bone Remodelling and Its Disruption in Metastatic Bone Disease

1991 • 10 citations