The positive inotropic effect of phenylephrine in the presence of propranolol. Increase in time to peak force and in relaxation time without increase in c-AMP

A Protein Binding Assay for Adenosine 3′:5′-Cyclic Monophosphate

1970 • 3,269 citations

Alpha sympathomimetic inhibition of adrenergic and cholinergic transmission in the rabbit heart

1972 • 293 citations

Cyclic AMP and contractile activity in heart.

1977 • 291 citations

Relaxing effects of catecholamines on mammalian heart

1972 • 205 citations

Cyclic AMP and contractile activity in heart.

1977 • 195 citations

Myocardial alpha adrenergic receptors and their role in the production of a positive inotropic effect by sympathomimetic agents.

1968 • 146 citations

Positive inotropic effects of phenylephrine in the isolated rabbit papillary muscle mediated both by ?-and ?-adrenoceptors

1974 • 135 citations

The time course of the effects of ?-and ?-adrenoceptor stimulation by isoprenaline and methoxamine on the contractile force and cAMP level of the isolated rabbit papillary muscle

1975 • 130 citations

Control of calcium transport in the myocardium by the cyclic AMP-Protein kinase system.

1975 • 102 citations

A positive inotropic effect of phenylephrine mediated through adrenergic receptors

1967 • 97 citations

STUDIES ON THE POSITIVE INOTROPIC EFFECT OF PHENYLEPHRINE: A COMPARISON WITH ISOPRENALINE

1975 • 90 citations

Interactions between sympathomimetic amines and blocking agents on the rat ventricle strip.

1966 • 87 citations

INTERACTIONS OF SYMPATHOMIMETIC DRUGS, PROPRANOLOL AND PHENTOLAMINE, ON ATRIAL REFRACTORY PERIOD AND CONTRACTILITY

1967 • 82 citations

Qualitative Differences between β‐Adrenergic and α‐Adrenergic Inotropic Effects in Rat Heart Muscle

1978 • 69 citations

alpha-Adrenergic reduction of cyclic adenosine monophosphate concentrations in rat myocardium.

1977 • 61 citations

Relationship between cyclic AMP metabolism and inotropic response of perfused rat hearts to phenylephrine and other adrenergic amines.

1975 • 54 citations

Characterization of α‐adrenoceptors in the myocardium

1973 • 52 citations

Analysis of the adrenergic receptors of pacemaker and myocardial cells

1972 • 47 citations

Effectiveness of theophylline to increase cyclic AMP levels and force of contraction in electrically paced guinea-pig auricles. Comparison with isoprenaline, calcium and ouabain

1977 • 46 citations

Possible role of cyclic AMP in the relaxation process of mammalian heart: Effects of dibutyryl cyclic AMP and theophylline on potassium contractures in cat papillary muscles

1976 • 43 citations

Characterization of the adrenoceptors mediating the positive ino- and chronotropic effect of phenylephrine on isolated atria from guinea pigs and rabbits by means of adrenolytic drugs

1974 • 40 citations

Relationship between the level of cAMP and the contractile force under stimulation of ?- and ?-adrenoceptors by phenylephrine in the isolated rabbit papillary muscle

1976 • 40 citations

Positive Inotropic Effect without Cyclic AMP Elevation after α–Adrenergic Stimulation of Perfused Hearts from Hypothyroid Rats

1976 • 32 citations

Drugs and Heart Muscle

1972 • 29 citations

Effects of isoprenaline and phenylephrine on energy‐rich phosphate compounds and glucose‐6‐phosphate in smooth and cardiac muscle

1971 • 26 citations

Biochemical and mechanical effects of phenylephrine on the heart

1976 • 24 citations

Phenylephrine-induced increases in cardiac contractility, cyclic adenosine monophosphate and phosphorylase a.

1973 • 22 citations

MECHANISM OF CARDIAC ACTIVITIES SYMPATHOMIMETIC AMINES ON ISOLATED AURICLES OF RABBITS.

1964 • 20 citations

Blockade of the cardiac action of phenylephrine by bretylium or cocaine.

1970 • 19 citations

THEOPHYLLINE AND PHENYLEPHRINE EFFECTS ON CARDIAC RELAXATION

1977 • 17 citations

The adrenergic receptors of the coronary circulation in the isolated dog heart.

1969 • 15 citations

Cyclic AMP and the positive inotropic effect of norepinephrine and phenylephrine

1977 • 11 citations

Role of adenylate cyclase-cyclic AMP in cardiac actions of adrenergic amines.

1973 • 10 citations