Positive inotropic effects of phenylephrine in the isolated rabbit papillary muscle mediated both by ?-and ?-adrenoceptors

SOME QUANTITATIVE USES OF DRUG ANTAGONISTS

1959 • 3,948 citations

Cumulative dose-response curves. II. Technique for the making of dose-response curves in isolated organs and the evaluation of drug parameters.

1963 • 1,214 citations

Some Aspects of the Biological Role of Adenosine 3',5'-monophosphate (Cyclic AMP)

1968 • 976 citations

The Classification of Adrenoceptors (Adrenergic Receptors). An Evaluation from the Standpoint of Receptor Theory

1972 • 812 citations

pA, A NEW SCALE FOR THE MEASUREMENT OF DRUG ANTAGONISM

1947 • 759 citations

Alpha sympathomimetic inhibition of adrenergic and cholinergic transmission in the rabbit heart

1972 • 293 citations

Inhibition of cyclic-3?,5?-nucleotide-phosphodiesterase as a possible mode of action of papaverine and similarly acting drugs

1970 • 252 citations

Myocardial alpha adrenergic receptors and their role in the production of a positive inotropic effect by sympathomimetic agents.

1968 • 146 citations

The potentiation of cardiac inotropic responses to norepinephrine by theophylline.

1963 • 139 citations

A positive inotropic effect of phenylephrine mediated through adrenergic receptors

1967 • 97 citations

Interactions between sympathomimetic amines and blocking agents on the rat ventricle strip.

1966 • 87 citations

INTERACTIONS OF SYMPATHOMIMETIC DRUGS, PROPRANOLOL AND PHENTOLAMINE, ON ATRIAL REFRACTORY PERIOD AND CONTRACTILITY

1967 • 82 citations

Role of Cyclic AMP and Ca⁺⁺ in Mechanical and Metabolic Events in Isometrically Contracting Vascular Smooth Muscle

1973 • 76 citations

Effect of catecholamines, histamine and oxyfedrine on isotonic contraction and cyclic AMP in the guinea-pig heart

1973 • 67 citations

Characterization of α‐adrenoceptors in the myocardium

1973 • 52 citations

Stimulation by phenylephrine of adrenergic alpha- and beta-receptors in the isolated perfused rabbit heart

1974 • 47 citations

Analysis of the adrenergic receptors of pacemaker and myocardial cells

1972 • 47 citations

Lack of relationship between myocardial cyclic AMP concentrations and inotropic effects of sympathomimetic amines

1971 • 45 citations

Sodium-angiotensin synergism in central regulation of water and salt metabolism.

1970 • 42 citations

Metabolic Actions in Intestinal Smooth Muscle Associated with Relaxation Mediated by Adrenergic α‐ and β‐Receptors

1970 • 41 citations

Characterization of the adrenoceptors mediating the positive ino- and chronotropic effect of phenylephrine on isolated atria from guinea pigs and rabbits by means of adrenolytic drugs

1974 • 40 citations

Effect of Phenylephrine on Cardiac Contractility and Adenyl Cyclase Activity

1971 • 40 citations

Effects of isoprenaline and phenylephrine on energy‐rich phosphate compounds and glucose‐6‐phosphate in smooth and cardiac muscle

1971 • 26 citations

The effects of theophylline, diazoxide and imidazole on isoproterenol-induced inhibition of the rabbit ileum.

1969 • 24 citations

MECHANISM OF CARDIAC ACTIVITIES SYMPATHOMIMETIC AMINES ON ISOLATED AURICLES OF RABBITS.

1964 • 20 citations

Blockade of the cardiac action of phenylephrine by bretylium or cocaine.

1970 • 19 citations

The adrenergic receptors of the coronary circulation in the isolated dog heart.

1969 • 15 citations

Phenylephrine effects on cardiac contractility adenyl cyclase, and phosphorylase.

1972 • 12 citations

Proceedings: Beta-and-or alpha-adrenoceptors in the ventricular muscle of the rabbit?

1974 • 8 citations