A conserved secondary structural motif in 23S rRNA defines the site of interaction of amicetin, a universal inhibitor of peptide bond formation.

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

The origin of the genetic code

1968 • 2,226 citations

Structure, Function, and Genetics of Ribosomes

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Interaction of tRNA with 23S rRNA in the ribosomal A, P, and E sites

1989 • 492 citations

RIBOSOMAL RNA AND TRANSLATION

1991 • 489 citations

Molecular Mechanisms of Protein Biosynthesis

1977 • 472 citations

Transformation methods for halophilic archaebacteria

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FURTHER CHARACTERIZATION OF PARTICULATE FRACTIONS FROM LYSED CELL ENVELOPES OF HALOBACTERIUM HALOBIUM AND ISOLATION OF GAS VACUOLE MEMBRANES

1968 • 238 citations

Ribosomes and protein synthesis, a practical approach

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What are antibiotics? Archaic functions for modern activities

1990 • 146 citations

Effects of some inhibitors of protein synthesis on the binding of aminoacyl tRNA to ribosomal subunits

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Inhibitors of protein synthesis by ribosomes of the 80-S type

1971 • 99 citations

Functional interactions within 23S rRNA involving the peptidyltransferase center

1992 • 95 citations

Defining the Structural Requirements for a Helix in 23 S Ribosomal RNA that Confers Erythromycin Resistance

1989 • 87 citations

Movement of tRNA but not the nascent peptide during peptide bond formation on ribosomes

1990 • 86 citations

Studies on the Formation of Transfer Ribonucleic Acid-Ribosome Complexes

1972 • 73 citations

Chloramphenicol resistance mutations in the single 23S rRNA gene of the archaeon Halobacterium halobium

1991 • 72 citations

Studies on the Formation of Transfer Ribonucleic Acid-Ribosome Complexes

1973 • 48 citations

Inhibitors of Protein Synthesis

1979 • 43 citations

Site-directed cross-linking studies on theE.colitRNA ribosome complex: determination of sites labelled with an aromatic azide attached to the variable loop or aminoacyl group of tRNA

1993 • 42 citations

Introducing mutations into the single-copy chromosomal 23S rRNA gene of the archaeon Halobacterium halobium by using an rRNA operon-based transformation system.

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BINDING OF BLASTICIDIN S TO RIBOSOMES

1970 • 30 citations

Synthetic studies on nucleoside antibiotics. 13. Inhibitors of protein synthesis. 4. Structure-activity relation of gougerotin and some of its analogs

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Evidence for RNA in the peptidyl transferase center of Escherichia coli ribosomes as indicated by fluorescence

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