Maturation of cellular Fe-S proteins: an essential function of mitochondria

Friedreich's Ataxia: Autosomal Recessive Disease Caused by an Intronic GAA Triplet Repeat Expansion

1996 • 2,667 citations

The genome sequence of Rickettsia prowazekii and the origin of mitochondria

1998 • 1,675 citations

Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress.

1996 • 1,311 citations

Aconitase and mitochondrial iron–sulphur protein deficiency in Friedreich ataxia

1997 • 975 citations

Regulation of Mitochondrial Iron Accumulation by Yfh1p, a Putative Homolog of Frataxin

1997 • 914 citations

The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins

1999 • 686 citations

Assembly of Iron-Sulfur Clusters

1998 • 632 citations

Cysteine desulfurase activity indicates a role for NIFS in metallocluster biosynthesis.

1993 • 579 citations

Copper coordination in blue proteins

2000 • 469 citations

Mutation of a Putative Mitochondrial Iron Transporter Gene (ABC7) in X-Linked Sideroblastic Anemia and Ataxia (XLSA/A)

1999 • 406 citations

Mechanism for the Desulfurization of L-Cysteine Catalyzed by the nifS Gene Product

1994 • 394 citations

Deletion of the yeast homologue of the human gene associated with Friedreich's ataxia elicits iron accumulation in mitochondria

1997 • 384 citations

NifS-directed assembly of a transient [2Fe-2S] cluster within the NifU protein

2000 • 316 citations

Evidence for a conserved system for iron metabolism in the mitochondria of Saccharomyces cerevisiae

1999 • 286 citations

The ABC transporter Atm1p is required for mitochondrial iron homeostasis

1997 • 278 citations

Human ABC7 transporter: gene structure and mutation causing X-linked sideroblastic anemia with ataxia with disruption of cytosolic iron-sulfur protein maturation

2000 • 268 citations

The State and Function of Copper in Biological Systems

1970 • 246 citations

Iron-sulfur clusters as biosensors of oxidants and iron.

1996 • 239 citations

Functional Assignment of the ORF2-iscS-iscU-iscA-hscB-hscA-fdx-0RF3 Gene Cluster Involved in the Assembly of Fe-S Clusters in Escherichia coli

1999 • 238 citations

Nitrogenase metalloclusters: structures, organization, and synthesis

1993 • 217 citations

An ABC transporter in the mitochondrial inner membrane is required for normal growth of yeast.

1995 • 200 citations

Saccharomyces cerevisiae ISU1 and ISU2: members of a well-conserved gene family for iron-sulfur cluster assembly

1999 • 192 citations

Yeast Mitochondrial Protein, Nfs1p, Coordinately Regulates Iron-Sulfur Cluster Proteins, Cellular Iron Uptake, and Iron Distribution

1999 • 192 citations

Steroidogenic electron transport in adrenal cortex mitochondria

1982 • 191 citations

Suppressors of Superoxide Dismutase (SOD1) Deficiency in Saccharomyces cerevisiae

1998 • 183 citations

NITROGENASE STRUCTURE AND FUNCTION: A Biochemical-Genetic Perspective

1995 • 178 citations

Targeting of a Human Iron–Sulfur Cluster Assembly Enzyme, nifs, to Different Subcellular Compartments Is Regulated through Alternative AUG Utilization

1998 • 177 citations

Mt-Hsp70 Homolog, Ssc2p, Required for Maturation of Yeast Frataxin and Mitochondrial Iron Homeostasis

1998 • 174 citations

Role of Saccharomyces cerevisiae ISA1and ISA2 in Iron Homeostasis

2000 • 168 citations

The Essential Role of Mitochondria in the Biogenesis of Cellular Iron-Sulfur Proteins

1999 • 158 citations

Low iron concentration and aconitase deficiency in a yeast frataxin homologue deficient strain

1999 • 147 citations

Crystal structure of a NifS-like protein from Thermotoga maritima: implications for iron sulphur cluster assembly

2000 • 142 citations

Identification of a human mitochondrial ABC transporter, the functional orthologue of yeast Atm1p

1998 • 140 citations

nifU Gene Product from Azotobacter vinelandii Is a Homodimer That Contains Two Identical [2Fe-2S] Clusters

1994 • 139 citations

Isa1p Is a Component of the Mitochondrial Machinery for Maturation of Cellular Iron-Sulfur Proteins and Requires Conserved Cysteine Residues for Function

2000 • 122 citations

Modular organization and identification of a mononuclear iron-binding site within the NifU protein

2000 • 119 citations

Structure of a NifS Homologue: X-ray Structure Analysis of CsdB, an Escherichia coli Counterpart of Mammalian Selenocysteine Lyase^,

2000 • 93 citations

POSTTRANSLATIONAL ASSEMBLY OF PHOTOSYNTHETIC METALLOPROTEINS

1998 • 81 citations

Mitochondrial Isa2p plays a crucial role in the maturation of cellular iron–sulfur proteins

2000 • 81 citations

The cold sensitivity of a mutant of Saccharomyces cerevisiae lacking a mitochondrial heat shock protein 70 is suppressed by loss of mitochondrial DNA.

1996 • 80 citations

Spectroscopic studies of Rhus vernicifera and Polyporus versicolor laccase. Electronic structures of the copper sites

1979 • 66 citations

Crystal structure of the cystine C-S lyase from Synechocystis : Stabilization of cysteine persulfide for FeS cluster biosynthesis

2000 • 65 citations

YAH1 of Saccharomyces cerevisiae: a new essential gene that codes for a protein homologous to human adrenodoxin

1999 • 63 citations

ARH1 ofSaccharomyces cerevisiae: A new essential gene that codes for a protein homologous to the human adrenodoxin reductase

1998 • 58 citations

A Novel l-Cysteine/Cystine C-S-Lyase Directing [2Fe-2S] Cluster Formation of SynechocystisFerredoxin

1997 • 54 citations

Characterization of Recombinant Adrenodoxin Reductase Homologue (Arh1p) from Yeast

1998 • 53 citations

cDNA cloning and characterization of mouse nifS‐like protein, m‐Nfs1: mitochondrial localization of eukaryotic NifS‐like proteins

1998 • 52 citations

Mitochondrial Iron Metabolism in the Yeast Saccharomyces cerevisiae

1999 • 44 citations

Evidence for Cysteine Persulfide as Reaction Product of l-Cyst(e)ine C-S-Lyase (C-DES) fromSynechocystis

1999 • 43 citations

Role of a NifS-like Protein from the Cyanobacterium Synechocystis PCC 6803 in the Maturation of FeS Proteins

2000 • 37 citations