Treatments for colorectal liver metastases: A new focus on a familiar concept
Data up to Jan 2025
Total Citations Per Year
Abstract
References (91)
Leucovorin and Fluorouracil With or Without Oxaliplatin as First-Line Treatment in Advanced Colorectal Cancer
2000 • 3,785 citations
Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial
2002 • 3,356 citations
Rescue Surgery for Unresectable Colorectal Liver Metastases Downstaged by Chemotherapy
2004 • 1,441 citations
Perioperative FOLFOX4 chemotherapy and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC 40983): long-term results of a randomised, controlled, phase 3 trial
2013 • 1,128 citations
Actual 10-Year Survival After Resection of Colorectal Liver Metastases Defines Cure
2007 • 1,089 citations
Tumor Progression While on Chemotherapy
2004 • 985 citations
Cancer Research UK
2002 • 967 citations
Hepatic Arterial Infusion of Chemotherapy after Resection of Hepatic Metastases from Colorectal Cancer
1999 • 923 citations
Tumour response and secondary resectability of colorectal liver metastases following neoadjuvant chemotherapy with cetuximab: the CELIM randomised phase 2 trial
2009 • 915 citations
Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11.
1991 • 855 citations
Complications of radiofrequency coagulation of liver tumours
2002 • 679 citations
Intrahepatic or Systemic Infusion of Fluorodeoxyuridine in Patients with Liver Metastases from Colorectal Carcinoma
1987 • 643 citations
A Prospective Randomized Trial of Regional Versus Systemic Continuous 5-Fluorodeoxyuridine Chemotherapy in the Treatment of Colorectal Liver Metastases
1987 • 572 citations
Multicenter Randomized Trial of Adjuvant Fluorouracil and Folinic Acid Compared With Surgery Alone After Resection of Colorectal Liver Metastases: FFCD ACHBTH AURC 9002 Trial
2006 • 560 citations
Image-Guided Tumor Ablation: Standardization of Terminology and Reporting Criteria—A 10-Year Update
2014 • 472 citations
Randomised phase 2 trial of SIR‐Spheres® plus fluorouracil/leucovorin chemotherapy versus fluorouracil/leucovorin chemotherapy alone in advanced colorectal cancer
2004 • 433 citations
American Society of Clinical Oncology 2009 Clinical Evidence Review on Radiofrequency Ablation of Hepatic Metastases From Colorectal Cancer
2009 • 432 citations
Metastatic pattern in colorectal cancer is strongly influenced by histological subtype
2014 • 424 citations
Systemic chemotherapy with or without cetuximab in patients with resectable colorectal liver metastasis: the New EPOC randomised controlled trial
2014 • 404 citations
Phase III Trial Comparing Protracted Intravenous Fluorouracil Infusion Alone or With Yttrium-90 Resin Microspheres Radioembolization for Liver-Limited Metastatic Colorectal Cancer Refractory to Standard Chemotherapy
2010 • 388 citations
Combined-Modality Treatment for Resectable Metastatic Colorectal Carcinoma to the Liver: Surgical Resection of Hepatic Metastases in Combination With Continuous Infusion of Chemotherapy—An Intergroup Study
2002 • 370 citations
Irreversible Electroporation for Nonthermal Tumor Ablation in the Clinical Setting: A Systematic Review of Safety and Efficacy
2014 • 359 citations
Randomized Trial of Surgery Versus Surgery Followed by Adjuvant Hepatic Arterial Infusion With 5-Fluorouracil and Folinic Acid for Liver Metastases of Colorectal Cancer
1998 • 357 citations
Selection of Patients for Resection of Hepatic Colorectal Metastases: Expert Consensus Statement
2006 • 341 citations
SIRFLOX: Randomized Phase III Trial Comparing First-Line mFOLFOX6 (Plus or Minus Bevacizumab) Versus mFOLFOX6 (Plus or Minus Bevacizumab) Plus Selective Internal Radiation Therapy in Patients With Metastatic Colorectal Cancer
2016 • 319 citations
Radioembolization of Liver Metastases From Colorectal Cancer Using Yttrium-90 Microspheres With Concomitant Systemic Oxaliplatin, Fluorouracil, and Leucovorin Chemotherapy
2007 • 308 citations
Randomized, Multicenter Trial of Fluorouracil Plus Leucovorin Administered Either Via Hepatic Arterial or Intravenous Infusion Versus Fluorodeoxyuridine Administered Via Hepatic Arterial Infusion in Patients With Nonresectable Liver Metastases From Colorectal Carcinoma
2000 • 306 citations
Intra-arterial infusion of irinotecan-loaded drug-eluting beads (DEBIRI) versus intravenous therapy (FOLFIRI) for hepatic metastases from colorectal cancer: final results of a phase III study.
2012 • 303 citations
Stereotactic body radiotherapy for colorectal liver metastases
2011 • 289 citations
Conversion to Resectability Using Hepatic Artery Infusion Plus Systemic Chemotherapy for the Treatment of Unresectable Liver Metastases From Colorectal Carcinoma
2009 • 283 citations
Predictors of Survival After Radiofrequency Thermal Ablation of Colorectal Cancer Metastases to the Liver: A Prospective Study
2005 • 263 citations
Five-year survival in 309 patients with colorectal liver metastases treated with radiofrequency ablation
2009 • 259 citations
A prospective, randomized evaluation of the treatment of colorectal cancer metastatic to the liver.
1990 • 249 citations
Clinical pharmacology of hepatic arterial chemotherapy.
1983 • 243 citations
Intrahepatic arterial versus intravenous fluorouracil and folinic acid for colorectal cancer liver metastases: a multicentre randomised trial
2003 • 235 citations
Radiation lobectomy: Time-dependent analysis of future liver remnant volume in unresectable liver cancer as a bridge to resection
2013 • 235 citations
Hepatic Arterial Oxaliplatin Infusion Plus Intravenous Chemotherapy in Colorectal Cancer With Inoperable Hepatic Metastases: A Trial of the Gastrointestinal Group of the Fédération Nationale des Centres de Lutte Contre le Cancer
2005 • 229 citations
Microwave coagulation therapy for multiple hepatic metastases from colorectal carcinoma
2000 • 226 citations
Microwave Ablation for Hepatic Malignancies
2013 • 223 citations
Multi-centre phase II clinical trial of yttrium-90 resin microspheres alone in unresectable, chemotherapy refractory colorectal liver metastases
2010 • 221 citations
Yttrium-90 microsphere radioembolization for the treatment of liver malignancies: a structured meta-analysis
2008 • 213 citations
Phase I Trial of Systemic Oxaliplatin Combination Chemotherapy With Hepatic Arterial Infusion in Patients With Unresectable Liver Metastases From Colorectal Cancer
2005 • 212 citations
Phase I Dose-Escalation Study of Stereotactic Body Radiotherapy in Patients With Hepatic Metastases
2010 • 203 citations
Local recurrence rates after radiofrequency ablation or resection of colorectal liver metastases. Analysis of the European Organisation for Research and Treatment of Cancer #40004 and #40983
2014 • 201 citations
Phase II trial of chemoembolization for the treatment of metastatic colorectal carcinoma to the liver and review of the literature
1998 • 196 citations
Radiofrequency thermal ablationof hepatic metastases
2001 • 194 citations
Irinotecan drug eluting beads for use in chemoembolization: In vitro and in vivo evaluation of drug release properties
2006 • 184 citations
Phase I Study of Hepatic Arterial Infusion of Floxuridine and Dexamethasone With Systemic Irinotecan for Unresectable Hepatic Metastases From Colorectal Cancer
2001 • 181 citations
Hepatic Arterial Infusion of Oxaliplatin and Intravenous LV5FU2 in Unresectable Liver Metastases from Colorectal Cancer after Systemic Chemotherapy Failure
2007 • 180 citations
Meta-Analysis of Hepatic Arterial Infusion for Unresectable Liver Metastases From Colorectal Cancer: The End of an Era?
2007 • 165 citations
Radiofrequency Ablation versus Resection for Resectable Colorectal Liver Metastases: Time for a Randomized Trial?
2008 • 163 citations
‘Liver First’ Approach in the Treatment of Colorectal Cancer with Synchronous Liver Metastases
2008 • 159 citations
Hepatic Parenchymal Preservation Surgery: Decreasing Morbidity and Mortality Rates in 4,152 Resections for Malignancy
2014 • 154 citations
Left-liver hypertrophy after therapeutic right-liver radioembolization is substantial but less than after portal vein embolization
2013 • 153 citations
Treatment of Fluorouracil-Refractory Patients With Liver Metastases From Colorectal Cancer by Using Yttrium-90 Resin Microspheres Plus Concomitant Systemic Irinotecan Chemotherapy
2009 • 152 citations
Adjuvant Chemotherapy Improves Survival after Resection of Hepatic Colorectal Metastases: Analysis of Data from Two Continents
2008 • 145 citations
Repeated Transarterial Chemoembolization in the Treatment of Liver Metastases of Colorectal Cancer: Prospective Study
2008 • 135 citations
Phase I/II Study of Hepatic Arterial Therapy With Floxuridine and Dexamethasone in Combination With Intravenous Irinotecan As Adjuvant Treatment After Resection of Hepatic Metastases From Colorectal Cancer
2003 • 133 citations
Chemoembolization of colorectal liver metastases with cisplatin, doxorubicin, mitomycin C, ethiodol, and polyvinyl alcohol
2010 • 130 citations
Metastatic colorectal cancer
2001 • 130 citations
Prolonged Survival of Initially Unresectable Hepatic Colorectal Cancer Patients Treated With Hepatic Arterial Infusion of Oxaliplatin Followed by Radical Surgery of Metastases
2010 • 124 citations
A prospective evaluation of treatment with Selective Internal Radiation Therapy (SIR-spheres) in patients with unresectable liver metastases from colorectal cancer previously treated with 5-FU based chemotherapy
2005 • 119 citations
Selective chemoembolization in the management of hepatic metastases in refractory colorectal carcinoma
1997 • 115 citations
Colorectal metastases to the liver: selective chemoembolization.
1993 • 114 citations
Randomized Phase II Trial of Adjuvant Hepatic Arterial Infusion and Systemic Chemotherapy With or Without Bevacizumab in Patients With Resected Hepatic Metastases From Colorectal Cancer
2010 • 114 citations
Debunking Dogma: Surgery for Four or More Colorectal Liver Metastases Is Justified
2006 • 108 citations
Comparison of Adjuvant Systemic Chemotherapy With or Without Hepatic Arterial Infusional Chemotherapy After Hepatic Resection for Metastatic Colorectal Cancer
2011 • 105 citations
Simultaneous resection for rectal cancer with synchronous liver metastasis is a safe procedure
2014 • 98 citations
Long-term Outcomes Following Tumor Ablation for Treatment of Bilateral Colorectal Liver Metastases
2013 • 95 citations
Phase I trial of adjuvant hepatic arterial infusion (HAI) with floxuridine (FUDR) and dexamethasone plus systemic oxaliplatin, 5-fluorouracil and leucovorin in patients with resected liver metastases from colorectal cancer
2009 • 90 citations
Locoregional surgical and interventional therapies for advanced colorectal cancer liver metastases: expert consensus statements
2013 • 90 citations
Radiofrequency ablation (RFA) combined with chemotherapy for unresectable colorectal liver metastases (CRC LM): Long-term survival results of a randomized phase II study of the EORTC-NCRI CCSG-ALM Intergroup 40004 (CLOCC).
2015 • 87 citations
Trans-arterial chemoembolization of metastatic colorectal carcinoma to the liver adopting DC Bead®, drug-eluting bead loaded with irinotecan: results of a phase II clinical study.
2011 • 86 citations
Alternating Systemic and Hepatic Artery Infusion Therapy for Resected Liver Metastases From Colorectal Cancer: A North Central Cancer Treatment Group (NCCTG)/ National Surgical Adjuvant Breast and Bowel Project (NSABP) Phase II Intergroup Trial, N9945/CI-66
2010 • 84 citations
Hepatic Toxicity After Radioembolization of the Liver Using 90Y-Microspheres: Sequential Lobar Versus Whole Liver Approach
2011 • 83 citations
Limited but definite efficacy of prophylactic hepatic arterial infusion chemotherapy after curative resection of colorectal liver metastases
2000 • 77 citations
Prospective randomised trial on adjuvant hepatic-artery infusion chemotherapy after R0 resection of colorectal liver metastases
1999 • 64 citations
Resection versus resection combined with adjuvant pre- and post-operative chemotherapy--immunotherapy for metastatic colorectal liver cancer. A new look at an old problem.
1995 • 64 citations
Transarterial Treatment of Colorectal Cancer Liver Metastases with Irinotecan-Loaded Drug-Eluting Beads: Technical Recommendations
2014 • 54 citations
Conversion to Complete Resection and/or Ablation Using Hepatic Artery Infusional Chemotherapy in Patients with Unresectable Liver Metastases from Colorectal Cancer: A Decade of Experience at a Single Institution
2013 • 52 citations
Treatment strategies for colorectal carcinoma with synchronous liver metastases: Which way to go?
2015 • 51 citations
Small Versus Large-Sized Drug-Eluting Beads (DEBIRI) for the Treatment of Hepatic Colorectal Metastases: A Propensity Score Matching Analysis
2014 • 42 citations
O-018 Radiofrequency ablation (RFA) combined with chemotherapy for unresectable colorectal liver metastases (CRC LM): Long-term survival results of a randomised phase II study of the EORTC-NCRI CCSG-ALM Intergroup 40004 (CLOCC)
2015 • 40 citations
Hepatic arterial infusion pump chemotherapy for colorectal liver metastases: an old technology in a new era
2013 • 35 citations
Trends in Nontherapeutic Laparotomy Rates in Patients Undergoing Surgical Therapy for Hepatic Colorectal Metastases
2008 • 35 citations
The effect of radiofrequency ablation vs. liver resection on survival outcome of colorectal liver metastases (CRLM): a meta-analysis.
2015 • 26 citations
COP1, the negative regulator of ETV1, influences prognosis in triple-negative breast cancer
2015 • 24 citations
Postoperative irinotecan in resected stage II–III rectal cancer: final analysis of the French R98 Intergroup trial
2015 • 10 citations
Ablative and Catheter-Directed Therapies for Colorectal Liver and Lung Metastases
2014 • 9 citations
Disease-Free Survival after Simultaneous or Delayed Resection of Synchronous Colorectal Liver Metastasis and Primary Cancer.
2014 • 9 citations
Hepatic intra-arterial chemotherapy using a percutaneous catheter in pretreated patients with metastatic colorectal carcinoma.
2004 • 8 citations
Cited By (0)
No citing papers found in database