A Prospective Randomized Trial of Regional Versus Systemic Continuous 5-Fluorodeoxyuridine Chemotherapy in the Treatment of Colorectal Liver Metastases

Evaluation of survival data and two new rank order statistics arising in its consideration.

1966 • 7,595 citations

The blood supply of neoplasms in the liver.

1954 • 1,280 citations

A clinical-pharmacological evaluation of hepatic arterial infusions of 5-fluoro-2'-deoxyuridine and 5-fluorouracil.

1978 • 516 citations

Pharmacologic rationale for regional drug delivery.

1984 • 451 citations

Regional chemotherapy of colorectal cancer metastatic to the liver

1984 • 254 citations

A Prospective Phase II Clinical Trial of Continuous FUDR Regional Chemotherapy for Colorectal Metastases to the Liver

1983 • 211 citations

Hepatic artery pump infusion: toxicity and results in patients with metastatic colorectal carcinoma.

1984 • 198 citations

Results of a prospective randomized study of hepatic artery infusion with 5-fluorouracil versus intravenous 5-fluorouracil in patients with hepatic metastases from colorectal cancer: A Central Oncology Group study.

1979 • 184 citations

A simplified plan for follow-up of patients with colon and rectal cancer supported by prospective studies of laboratory and radiologic test results.

1987 • 175 citations

Biliary sclerosis in patients receiving hepatic arterial infusions of floxuridine.

1985 • 173 citations

The blood supply of experimental liver metastases. II. A microcirculatory study of the normal and tumor vessels of the liver with the use of perfused silicone rubber.

1970 • 173 citations

Chemotherapy of Metastatic Liver Cancer by Prolonged Hepatic-Artery Infusion

1964 • 170 citations

Sclerosing Cholangitis after Continuous Hepatic Artery Infusiori of FUDR

1985 • 156 citations

Intraarterial infusion chemotherapy for hepatic carcinoma using a totally implantable infusion pump

1980 • 148 citations

Lymphatic dissemination of hepatic metastases. Implications for the follow-up and treatment of patients with colorectal cancer

1985 • 131 citations

Long-term hepatic arterial infusion of 5-fluorodeoxyuridine for liver metastases using an implantable infusion pump.

1983 • 127 citations

Intra-arterial chemotherapy using an implantable infusion pump and liver irradiation for the treatment of hepatic metastases

1982 • 116 citations

Therapy for metastatic colorectal cancer with hepatic artery infusion chemotherapy using a subcutaneous implanted pump.

1985 • 112 citations

Surgical considerations in the management of hepatic neoplasia.

1983 • 100 citations

Multivariate Analysis of a Personal Series of 247 Patients with Liver Metastases from Colorectal Cancer

1984 • 95 citations

The design and initial testing of an implantable infusion pump.

1972 • 94 citations

Regional hepatic chemotherapy using an implantable drug infusion pump

1983 • 84 citations

A phase i study of intravenous iododeoxyuridine as a clinical radiosensitizer

1985 • 81 citations

Hepatic arterial infusion with floxuridine and cisplatin: overriding importance of antitumor effect versus degree of tumor burden as determinants of survival among patients with colorectal cancer.

1986 • 30 citations

Regional Management of Liver Metastases. II

1983 • 20 citations

Preliminary Results of a Randomized Study of Intrahepatic Infusion Versus Systemic Infusion of 5-Fluoro-2′ -deoxyuridine for Metastatic Colorectal Carcinoma

1986 • 17 citations

Regional Management of Liver Metastases. I

1983 • 15 citations