The Excitotoxic Concept

Glutamate neurotoxicity and diseases of the nervous system

1988 • 7,257 citations

Cloned Glutamate Receptors

1994 • 3,989 citations

Elevation of the Extracellular Concentrations of Glutamate and Aspartate in Rat Hippocampus During Transient Cerebral Ischemia Monitored by Intracerebral Microdialysis

1984 • 2,884 citations

Excitotoxic cell death

1992 • 2,307 citations

Brain Lesions, Obesity, and Other Disturbances in Mice Treated with Monosodium Glutamate

1969 • 1,802 citations

Calcium Fluxes, Calcium Antagonists, and Calcium-Related Pathology in Brain Ischemia, Hypoglycemia, and Spreading Depression: A Unifying Hypothesis

1989 • 1,237 citations

Excitotoxity and the NMDA receptor

1987 • 1,053 citations

Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress

1989 • 987 citations

Glutamate becomes neurotoxic via the N-methyl-d-aspartate receptor when intracellular energy levels are reduced

1988 • 972 citations

Possible Therapeutic Applications of Antagonists of Excitatory Amino acid Neurotransmitters

1985 • 558 citations

Glutamate receptor channels: novel properties and new clones

1992 • 427 citations

Switch in glutamate receptor subunit gene expression in CA1 subfield of hippocampus following global ischemia in rats.

1992 • 399 citations

Hundred-fold increase in neuronal vulnerability to glutamate toxicity in astrocyte-poor cultures of rat cerebral cortex

1989 • 390 citations

Methods for antagonizing glutamate neurotoxicity.

1990 • 277 citations