DOPAMINE AND HUNTINGTON'S DISEASE: ASSESSMENT USING THE KAINIC ACID MODEL

Nonparametric Statistical Methods.

1974 • 2,964 citations

Brain dopamine and the syndromes of Parkinson and Huntington Clinical, morphological and neurochemical correlations

1973 • 2,615 citations

Verteilung Von Noradrenalin Und Dopamin (3-Hydroxytyramin) Im Gehirn Des Menschen Und Ihr Verhalten Bei Erkrankungen Des Extrapyramidalen Systems

1960 • 1,863 citations

Lesion of striatal neurons with kainic acid provides a model for Huntington's chorea

1976 • 1,247 citations

Huntington's Chorea

1973 • 845 citations

Duplication of biochemical changes of Huntington's chorea by intrastriatal injections of glutamic and kainic acids

1976 • 832 citations

CATECHOLAMINES IN FETAL AND NEWBORN RAT BRAIN

1973 • 785 citations

Immunohistochemical studies using antibodies to leucine-enkephalin: Initial observations on the nervous system of the rat

1976 • 767 citations

The distribution of enkephalin-immunoreactive cell bodies in the rat central nervous system

1977 • 690 citations

Simultaneous measurement of tyrosine and tryptophan hydroxylase activities in brain in Vivo using an inhibitor of the aromatic amino acid decarboxylase

1972 • 649 citations

HUNTINGTON'S CHOREA

1974 • 527 citations

Striatal lesions with kainic acid: neurochemical characteristics

1977 • 461 citations

ENZYMES ASSOCIATED WITH THE METABOLISM OF CATECHOLAMINES, ACETYLCHOLINE AND GABA IN HUMAN CONTROLS AND PATIENTS WITH PARKINSON'S DISEASE AND HUNTINGTON'S CHOREA

1976 • 452 citations

Dopamine receptors localised on cerebral cortical afferents to rat corpus striatum

1978 • 401 citations

Metabolism of amines in the brain.

1969 • 321 citations

Enkephalin receptors on dopaminergic neurones in rat striatum

1977 • 312 citations

A method for the determination of 3,4-dihydroxyphenylalanine (DOPA) in brain

1972 • 273 citations

Direct evidence for presynaptic and postsynaptic dopamine receptors in brain

1978 • 210 citations

Huntington's Chorea

1976 • 180 citations

A Pharmacologic Analysis of Huntington’s Chorea

1970 • 146 citations

Evidence for a decrease in substance P content of substantia nigra in Huntington's chorea

1977 • 130 citations

Clinical, neuropathologic and pharmacologic aspects of Huntington's disease: Correlates with a new animal model

1977 • 121 citations

Microfluorimetric quantitation of catecholamine fluorescence in rat median eminence. II. Turnover changes in hormonal states.

1976 • 107 citations

On the locaticn of methicnine enkephalin neurons in rat striatum

1977 • 93 citations

Alterations in dopaminergic receptors in Huntington's disease

1977 • 89 citations

GABA receptor binding in rat striatum: Localization and effects of denervation

1977 • 58 citations

Alterations in 3H-GABA binding in Huntington's chorea

1977 • 56 citations

Apomorphine Hydrochloride-Induced Improvement in Huntington's Chorea

1978 • 56 citations

Changes in striatal specific 3H-atropine binding after unilateral 6-hydroxydopamine lesions of nigrostriatal dopaminergic neurones

1978 • 52 citations

The regulation of the kinetic state of striatal tyrosine hydroxylase and the role of postsynaptic dopamine receptors

1975 • 31 citations

Athetoid and choreiform hyperkinesias produced by caudate application of dopamine in cats

1972 • 29 citations

POSSIBLE PATHOGENESIS OF HUNTINGTON'S CHOREA AND A NEW APPROACH TO TREATMENT

2009 • 29 citations

TREATMENT OF HUNTINGTON'S CHOREA WITH BROMOCRIPTINE

2009 • 28 citations

A pharmacologic model of Huntington's chorea

1976 • 6 citations