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Simultaneous measurement of tyrosine and tryptophan hydroxylase activities in brain in Vivo using an inhibitor of the aromatic amino acid decarboxylase

Data up to Jan 2025

Published1972
Citations649
References25

Total Citations Per Year

Abstract

References (25)

Application of steady state kinetics to the estimation of synthesis rate and turnover time of tissue catecholamines.

1966 • 709 citations

A Fluorimetric Method for the Determination of Dopamine (3‐Hydroxytyramine.)

1958 • 622 citations

B. TYROSINE HYDROXYLASE

1966 • 493 citations

APPLICATION OF STEADY STATE KINETICS TO THE SYNTHESIS RATE AND TURNOVER TIME OF SEROTONIN IN THE BRAIN OF NORMAL AND RESERPINE-TREATED RATS

1966 • 311 citations

A method for the determination of 3,4-dihydroxyphenylalanine (DOPA) in brain

1972 • 273 citations

Individual elution of noradrenaline (together with adrenaline), dopamine, 5-hydroxytryptamine and histamine from a single, strong cation exchange column, by means of mineral acid-organic solvent mixtures

1970 • 243 citations

Selective release of newly synthesized norepinephrine from the cat spleen during sympathetic nerve stimulation.

1968 • 242 citations

A simple procedure for calculating the synthesis rate of norepinephrine, dopamine and serotonin in rat brain.

1971 • 183 citations

The rate of norepinephrine synthesis measured in vivo during short intervals; influence of adrenergic nerve impulse activity.

1968 • 172 citations

Inhibition of dopa decarboxylase by the hydrazino analog of α-methyldopa

1962 • 166 citations

DYNAMIC CHARACTERISTICS OF THE 'FUNCTIONAL COMPARTMENT' OF DOPAMINE IN DOPAMINERGIC TERMINALS OF THE RAT STRIATUM

1971 • 164 citations

Effect of a transverse cerebral hemisection on 5-hydroxytryptamine metabolism in the rat brain

1972 • 133 citations

The effect of L-tryptophan and some psychotropic drugs on the formation of 5-hydroxytryptophan in the mouse brain in vivo

1972 • 89 citations

Hydroxytryptamine turnover decreased by the antidepressant drug chlorimipramine

1970 • 82 citations

In vivo measurement of 5-hydroxytryptamine turnover rate in the rat brain from the conversion of C14-tryptophan to C14-5-hydroxytryptamine.

1969 • 77 citations

Quantitative Estimation of 5-Hydroxy-3-Indole Acetic Acid and 5-Hydroxytryptophan in the Brain Following Isolation by Means of a Strong Cation Exchange Column

1971 • 75 citations

Calculation of the rate of catecholamine synthesis from the rate of conversion of tyrosine-14C to catecholamines. Effect of adrenal demedullation on synthesis rates.

1969 • 50 citations

L-dopa-induced accumulation of 3-O-methyldopa in brain and heart

1970 • 45 citations

Regional effects of L-dihydroxyphenylalanine (L-dopa) on norepinephrine metabolism in rat brain.

1972 • 36 citations

Accumulation of 5-hydroxytryptophan in mouse brain after decarboxylase inhibition

1970 • 31 citations

Tyrosine hydroxylase.

1966 • 30 citations

Origin of 5-hydroxytryptophan and L-dopa accumulating in brain following decarboxylase inhibition

1971 • 29 citations

Mechanism of release of α-methylated noradrenaline analogues by monoamine oxidase inhibitors

1968 • 10 citations

Effect of decarboxylase inhibition and neuroleptic drugs on the DOPA level in rat brain.

1970 • 6 citations

Inhibition of tyrosine degradation in vivo by the dopa decarboxylase blocking agent NSD-1034

1968 • 3 citations

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Simultaneous measurement of tyrosine and tryptophan hydroxylase activities in brain in… (1972) – Naunyn-Schmiedeberg s Archives of Pharmacology | Metascience Observatory Explorer