Clinical, neuropathologic and pharmacologic aspects of Huntington's disease: Correlates with a new animal model

Brain dopamine and the syndromes of Parkinson and Huntington Clinical, morphological and neurochemical correlations

1973 • 2,615 citations

Postsynaptic Supersensitivity after 6‐Hydroxy‐dopamine Induced Degeneration of the Nigro‐striatal Dopamine System

1971 • 1,922 citations

Lesion of striatal neurons with kainic acid provides a model for Huntington's chorea

1976 • 1,247 citations

Huntington's Chorea

1973 • 845 citations

Duplication of biochemical changes of Huntington's chorea by intrastriatal injections of glutamic and kainic acids

1976 • 832 citations

Psychiatric Aspects of Neurologic Disease

1976 • 674 citations

Striatal lesions with kainic acid: neurochemical characteristics

1977 • 461 citations

ENZYMES ASSOCIATED WITH THE METABOLISM OF CATECHOLAMINES, ACETYLCHOLINE AND GABA IN HUMAN CONTROLS AND PATIENTS WITH PARKINSON'S DISEASE AND HUNTINGTON'S CHOREA

1976 • 452 citations

GLUTAMATE—INDUCED RETINAL DEGENERATION IN NEONATAL MICE. ELECTRON MICROSCOPY OF THE ACUTELY EVOLVING LESION

1969 • 352 citations

Antagonism of cortical excitation of striatal neurons by glutamic acid diethyl ester: Evidence for glutamic acid as an excitatory transmitter in the rat striatum

1976 • 343 citations

Morphometric studies of the neuropathological changes in choreatic diseases

1976 • 319 citations

BINDING OF [³H]KAINIC ACID, AN ANALOGUE OF <scp>l</scp>‐GLUTAMATE, TO BRAIN MEMBRANES

1976 • 308 citations

On the source of gaba-containing terminals in the substantia nigra. Electron microscopic autoradiographic and biochemical studies

1973 • 286 citations

Caudate nucleus neurones: correlation of the effects of substantia nigra stimulation with iontophoretic dopamine

1970 • 271 citations

Excitation of mammalian central neurones by acidic amino acids

1972 • 239 citations

Excitatory nature of dopamine in the nigro-caudate pathway

1976 • 212 citations

Huntington's Chorea

1976 • 180 citations

Electrophysiological evidence for involvement of cyclic adenosine monophosphate in dopamine responses of caudate neurons

1974 • 162 citations

Central cholinergic‐anticholinergic antagonism in Huntington's chorea

1972 • 150 citations

A Pharmacologic Analysis of Huntington’s Chorea

1970 • 146 citations

Neurochemical sequelae of kainate injections in corpus striatum and substantia nigra of the rat

1977 • 144 citations

Brain mechanisms in mental retardation

1976 • 133 citations

Alterations of brain neurotransmitter receptor binding in Huntington's chorea

1976 • 132 citations

Light- and electron-microscopic changes in central nervous tissue after electrophoretic injection of glutamate

1971 • 112 citations

Use of L-Dopa in the Detection of Presymptomatic Huntington's Chorea

1972 • 102 citations

GABA CONTENT AND GLUTAMIC ACID DECARBOXYLASE ACTIVITY IN BRAIN OF HUNTINGTON'S CHOREA PATIENTS AND CONTROL SUBJECTS¹

1975 • 94 citations

Regional distribution of choline acetyltransferase in the human brain: changes in Huntington's chorea.

1975 • 90 citations

Huntington's Disease

1975 • 82 citations

In vivo actions of clozapine and haloperidol on the turnover rate of acetylcholine in rat striatum.

1976 • 82 citations

Huntington's disease

1976 • 74 citations

Modification of striatal acetylcholine concentration by dopamine receptor agonists and antagonists.

1974 • 74 citations

Water uptake and energy metabolism in brain slices from the rat

1970 • 70 citations

Huntington's Disease: Regional alteration in muscarinic cholinergic receptor binding in human brain

1976 • 65 citations

Loss of striatal serotonin synaptic receptor binding induced by kainic acid lesions: correlations with Huntington's Disease¹

1977 • 63 citations

GABA receptor binding in rat striatum: Localization and effects of denervation

1977 • 58 citations

A sex related factor in the inheritance of Huntington's chorea

1974 • 57 citations

Relationship between animal models and clinical parkinsonism.

1975 • 52 citations

Receptors for amino acids in excitable tissues

1976 • 51 citations

Fibroblasts in Huntington's Disease

1975 • 42 citations

Fibroblast Cultures in Huntington's Disease

1973 • 42 citations

Mutation in Huntington's chorea.

1969 • 36 citations

DIMETHYL AMINOETHANOL IN HUNTINGTON'S CHOREA

1973 • 26 citations

Biochemistry and Neurology

1976 • 18 citations

Effects of Caudate Nuclei Removal in Cats. Comparison with Effects of Frontal Cortex Ablation

1975 • 17 citations

Huntington’s Disease of Young People

1970 • 16 citations

Huntington's chorea. A study of liver function and histology.

1973 • 15 citations