Regulation of human embryonic globin genes zeta 2 and epsilon in stably transformed mouse erythroleukemia cells

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Evidence for a locus activation region: the formation of developmentally stable hypersensitive sites in globin-expressing hybrids

1987 • 440 citations

Developmental regulation of human fetal-to-adult globin gene switching in transgenic mice

1990 • 364 citations

A dominant control region from the human β-globin locus conferring integration site-independent gene expression

1989 • 346 citations

Definition of the minimal requirements within the human beta-globin gene and the dominant control region for high level expression.

1990 • 322 citations

The β-globin dominant control region activates homologous and heterologous promoters in a tissue-specific manner

1989 • 302 citations

A single erythroid-specific DNase I super-hypersensitive site activates high levels of human beta-globin gene expression in transgenic mice.

1989 • 269 citations

Rapid reprogramming of globin gene expression in transient heterokaryons

1986 • 246 citations

Haemoglobin switching in human embryos: asynchrony of ζ → α and ε → γ-globin switches in primitive and definitive erythropoietic lineage

1985 • 218 citations

An embryonic pattern of expression of a human fetal globin gene in transgenic mice

1986 • 204 citations

Human globin locus activation region (LAR): role in temporal control

1990 • 189 citations

Identification of a transcriptional silencer in the 5'-flanking region of the human epsilon-globin gene.

1989 • 158 citations

Autonomous Developmental Control of Human Embryonic Globin Gene Switching in Transgenic Mice

1990 • 151 citations

Demonstration of a human epsilon-globin gene silencer with studies in transgenic mice

1992 • 79 citations

Developmentally regulated and erythroid-specific expression of the human embryonic β-globin gene in transgenic mice

1990 • 68 citations

A factor binding GATAAG confers tissue specificity on the promoter of the humanζ-globin gene

1990 • 47 citations

Coexpression of embryonic, fetal, and adult globins in erythroid cells of human embryos: Relevance to the cell-lineage models of globin switching

1987 • 41 citations

Regulation of human fetal and adult globin genes in mouse erythroleukemia cells

1991 • 33 citations

Developmental regulation of the human zeta globin gene in transgenic mice

1990 • 25 citations