Demonstration of a human epsilon-globin gene silencer with studies in transgenic mice

Position-independent, high-level expression of the human β-globin gene in transgenic mice

1987 • 1,955 citations

The "beta-like-globin" gene domain in human erythroid cells.

1985 • 634 citations

A developmentally stable chromatin structure in the human beta-globin gene cluster.

1986 • 391 citations

Developmental regulation of human fetal-to-adult globin gene switching in transgenic mice

1990 • 364 citations

A dominant control region from the human β-globin locus conferring integration site-independent gene expression

1989 • 346 citations

The β-globin dominant control region activates homologous and heterologous promoters in a tissue-specific manner

1989 • 302 citations

Human gamma- to beta-globin gene switching in transgenic mice.

1990 • 291 citations

A single erythroid-specific DNase I super-hypersensitive site activates high levels of human beta-globin gene expression in transgenic mice.

1989 • 269 citations

Rapid reprogramming of globin gene expression in transient heterokaryons

1986 • 246 citations

The primary structure of the human ε-globin gene

1980 • 195 citations

Identification of a transcriptional silencer in the 5'-flanking region of the human epsilon-globin gene.

1989 • 158 citations

The human beta-globin locus activation region alters the developmental fate of a human fetal globin gene in transgenic mice.

1989 • 112 citations

Multiple origins of transcription in the 4.5 Kb upstream of the ϵ-globin gene

1983 • 98 citations

High-level, erythroid-specific expression of the human alpha-globin gene in transgenic mice and the production of human hemoglobin in murine erythrocytes.

1989 • 83 citations

Developmentally regulated and erythroid-specific expression of the human embryonic β-globin gene in transgenic mice

1990 • 68 citations

An immunoassay to detect human embryonic epsilon globin chains by a murine monoclonal antibody

1988 • 16 citations