Gangliosides as modulators of cell function

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid.

1980 • 1,997 citations

Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ER

1989 • 1,685 citations

Terminal differentiation of human promyelocytic leukemia cells induced by dimethyl sulfoxide and other polar compounds.

1978 • 1,624 citations

RECEPTORS FOR EPIDERMAL GROWTH FACTOR AND OTHER POLYPEPTIDE MITOGENS

1987 • 1,274 citations

Demonstration by monoclonal antibodies that carbohydrate structures of glycoproteins and glycolipids are onco-developmental antigens

1985 • 1,184 citations

Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets.

1986 • 1,150 citations

Bifunctional role of glycosphingolipids. Modulators for transmembrane signaling and mediators for cellular interactions.

1990 • 889 citations

Ganglioside-mediated modulation of cell growth. Specific effects of GM3 on tyrosine phosphorylation of the epidermal growth factor receptor.

1986 • 702 citations

Progress in Unraveling Pathways of Golgi Traffic

1985 • 615 citations

Lysosphingolipids Inhibit Protein Kinase C: Implications for the Sphingolipidoses

1987 • 593 citations

Topoinhibition and Serum Requirement of Transformed and Untransformed Cells

1970 • 444 citations

Induction of monocytic differentiation and bone resorption by 1,25-dihydroxyvitamin D3.

1983 • 424 citations

Role of membrane gangliosides in the binding and action of bacterial toxins

1982 • 396 citations

Biology of gangliosides: Neuritogenic and neuronotrophic properties

1984 • 314 citations

Über die Ganglioside, eine neue Gruppe von zuckerhaltigen Gehirnlipoiden

1942 • 301 citations

Intracellular translocation of fluorescent sphingolipids in cultured fibroblasts: endogenously synthesized sphingomyelin and glucocerebroside analogues pass through the Golgi apparatus en route to the plasma membrane.

1985 • 297 citations

A multivalent lacto-N-fucopentaose III-lysyllysine conjugate decompacts preimplantation mouse embryos, while the free oligosaccharide is ineffective.

1984 • 291 citations

Ganglioside inhibition of fibronectin-mediated cell adhesion to collagen.

1979 • 259 citations

Extracellular Matrix Assembly

1988 • 250 citations

Gangliosides enhance neurite outgrowth in PC12 cells

1983 • 249 citations

Compartmentation of the Golgi complex: brefeldin-A distinguishes trans-Golgi cisternae from the trans-Golgi network.

1990 • 222 citations

Ganglioside Biosynthesis

1974 • 218 citations

Activation of (Na⁺, K⁺)‐ATPase by Nanomolar Concentrations of GM₁ Ganglioside

1981 • 212 citations

Oligosaccharides containing fucose linked α(1–3) and α(1–4) to N-acetylglucosamine cause decompaction of mouse morulae

1984 • 193 citations

Cell Density-Dependent Changes of Glycolipid Concentrations in Fibroblasts, and Loss of This Response in Virus-Transformed Cells

1970 • 190 citations

A cell surface molecule distributed in a dorsoventral gradient in the perinatal rat retina

1986 • 188 citations

COMPOSITION OF GANGLIOSIDES AND PHOSPHOLIPIDS OF NEURONAL AND GLIAL CELL ENRICHED FRACTIONS¹

1971 • 188 citations

Glycoconjugate expression during embryogenesis and its biological significance

1990 • 186 citations

A novel ganglioside, de-N-acetyl-GM3 (II3NeuNH2LacCer), acting as a strong promoter for epidermal growth factor receptor kinase and as a stimulator for cell growth.

1988 • 183 citations

Calcium/Ganglioside‐Dependent Protein Kinase Activity in Rat Brain Membrane

1985 • 170 citations

Exogenous glycosphingolipids suppress growth rate of transformed and untransformed 3T3 mouse cells

1975 • 135 citations

Glycolipids and transmembrane signaling: antibodies to galactocerebroside cause an influx of calcium in oligodendrocytes.

1990 • 131 citations

Induction of differentiation of cultured human promyelocytic leukemia cells by retinoids

1980 • 119 citations

Cell density dependent glycolipids in NIL2 hamster cells, derived malignant and transformed cell lines

1973 • 106 citations

Transmembrane signaling by the B subunit of cholera toxin: increased cytoplasmic free calcium in rat lymphocytes.

1987 • 96 citations

STUDIES ON BRAIN GANGLIOSIDES: III. EVIDENCE FOR THE LOCATION OF GANGLIOSIDES SPECIFICALLY IN NEURONES

1964 • 92 citations

Ganglioside biosynthesis in mouse cells: Glycosyltransferase activities in normal and virally-transformed lines

1972 • 87 citations

Distribution of gangliosides among subcellular fractions from rat liver and bovine mammary gland

1972 • 79 citations

Gangliosides inhibit phospholipid‐sensitive Ca²⁺‐dependent kinase phosphorylation of rat myelin basic proteins

1986 • 74 citations

[44] Gangliosides that modulate membrane protein function

1989 • 72 citations

Gangliosides as Receptors for Bacterial Toxins and Sendai Virus

1980 • 65 citations

Ganglioside-modulated protein phosphorylation in myelin.

1987 • 64 citations

Synergism between membrane gangliosides and Arg-Gly-Asp-directed glycoprotein receptors in attachment to matrix proteins by melanoma cells.

1988 • 61 citations

Reevaluation of the Role of Gangliosides as Receptors for Tetanus Toxin

1986 • 60 citations

Modified ganglioside as a possible modulator of transmembrane signaling mechanism through growth factor receptors: A preliminary note

1987 • 59 citations

The Lipid Composition of Rat CNS Axolemma‐enriched Fractions

1980 • 53 citations

Gangliosides and their cell density-dependent changes in control and chemically transformed C3H/10T1/2 cells

1978 • 52 citations

Glycolipid glycosyltransferases in human embryonal carcinoma cells during retinoic acid induced differentiation

1989 • 50 citations

Biosynthesis of Brain Gangliosides

1976 • 48 citations

Botulinum A neurotoxin unlike tetanus toxin acts via a neuraminidase sensitive structure

1986 • 48 citations

Ganglioside biosynthesis in rat liver

1986 • 46 citations

Stage-specific embryonic antigen 3 as a marker of visceral extraembryonic endoderm

1984 • 44 citations

Ganglioside Composition of Normal and Mutant Mouse Embryos

1989 • 41 citations

Ganglioside biosynthesis in rat liver characterization of cytidine-5′-monophospho-n-acetylneuraminic acid: Hematoside (Gm3) sialyltransferase

1980 • 39 citations

A role of carbohydrate-carbohydrate interaction in the process of specific cell recognition during embryogenesis and organogenesis: A preliminary note

1989 • 39 citations

Subcellular distribution of glycolipids in a hamster cell line

1973 • 37 citations

Glycosphingolipids of normal and leukemic human leukocytes

1982 • 37 citations

Altered Expression of the D1.1 Ganglioside in the Cerebellum of the Weaver Mouse

1988 • 20 citations

Effect of bacterial toxins on human B cell activation. II. Mitogenic activity of the B subunit of cholera toxin

1991 • 18 citations

Glycolipid glycosyl transferases of a hamster cell line in culture II. Subcellular distribution and the effect of culture age and density

1976 • 18 citations

Glycosphingolipids in Secondary Lysosomes Prepared from Rat Liver

1974 • 12 citations

Characterization of a soluble glycolipid galactosyltransferase which occurs in bovine milk

1979 • 10 citations

Increased sialylation of complex glycopeptides during differentiation of mouse embryonal carcinoma cells

1985 • 9 citations

IDENTIFICATION OF GANGLIOSIDES AS CONSTITUENTS OF EGG YOLK

1973 • 5 citations