Variability of integrin alpha 2 beta 1 activity on human platelets

High resolution two-dimensional electrophoresis of proteins.

1975 • 19,515 citations

Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

1991 • 2,981 citations

[2] Preparation and characterization of the different types of collagen

1982 • 758 citations

Integrin adhesion molecules in the human endometrium. Correlation with the normal and abnormal menstrual cycle.

1992 • 643 citations

Amino acid sequence of the human fibronectin receptor.

1987 • 596 citations

Purification of fibronectin from human plasma by affinity chromatography under non-denaturing conditions

1979 • 553 citations

Human blood platelets showing no response to collagen fail to express surface glycoprotein Ia

1985 • 518 citations

A patient with platelets deficient in glycoprotein VI that lack both collagen-induced aggregation and adhesion.

1989 • 468 citations

Identification of a tetrapeptide recognition sequence for the alpha 2 beta 1 integrin in collagen.

1991 • 401 citations

Effect of shear rate on platelet interaction with subendothelium in citrated and native blood. I. Shear rate--dependent decrease of adhesion in von Willebrand's disease and the Bernard-Soulier syndrome.

1978 • 368 citations

Monoclonal antibodies to ligand-occupied conformers of integrin alpha IIb beta 3 (glycoprotein IIb-IIIa) alter receptor affinity, specificity, and function.

1991 • 367 citations

The primary structure of the VLA-2/collagen receptor alpha 2 subunit (platelet GPIa): homology to other integrins and the presence of a possible collagen-binding domain.

1989 • 343 citations

Selective inhibition of integrin function by antibodies specific for ligand-occupied receptor conformers.

1990 • 328 citations

Collagen-platelet interactions: evidence for a direct interaction of collagen with platelet GPIa/IIa and an indirect interaction with platelet GPIIb/IIIa mediated by adhesive proteins

1989 • 305 citations

Affinity modulation of the alpha IIb beta 3 integrin (platelet GPIIb-IIIa) is an intrinsic property of the receptor.

1990 • 285 citations

Occupancy of an adhesive glycoprotein receptor modulates expression of an antigenic site involved in cell adhesion.

1988 • 280 citations

The human fibroblast class II extracellular matrix receptor mediates platelet adhesion to collagen and is identical to the platelet glycoprotein Ia-IIa complex.

1988 • 258 citations

Extracellular matrix receptors, ECMRII and ECMRI, for collagen and fibronectin correspond to VLA-2 and VLA-3 in the VLA family of heterodimers

1988 • 218 citations

Deficiency of platelet membrane glycoprotein Ia associated with a decreased platelet adhesion to subendothelium: a defect in platelet spreading

1986 • 211 citations

Deficiency of intact thrombospondin and membrane glycoprotein Ia in platelets with defective collagen-induced aggregation and spontaneous loss of disorder

1988 • 194 citations

A conformation-dependent epitope of human platelet glycoprotein IIIa

1990 • 162 citations

Use of the monoclonal antibody 12F1 to characterize the differentiation antigen VLA-2.

1987 • 154 citations

Isolation and characterization of a platelet surface collagen binding complex related to VLA-2

1988 • 152 citations

Platelet-collagen adhesion: inhibition by a monoclonal antibody that binds glycoprotein IIb.

1984 • 148 citations

Multiple functional forms of the integrin VLA-2 can be derived from a single alpha 2 cDNA clone: interconversion of forms induced by an anti-beta 1 antibody.

1993 • 141 citations

The alpha 2 beta 1 integrin cell surface collagen receptor binds to the alpha 1 (I)-CB3 peptide of collagen.

1990 • 137 citations

Glycoprotein Ic-IIa functions as an activation-independent fibronectin receptor on human platelets.

1988 • 137 citations

Platelet glycoproteins Ia, Ic, and IIa are physicochemically indistinguishable from the very late activation antigens adhesion-related proteins of lymphocytes and other cell types.

1988 • 127 citations

An alternative form of the integrin beta 1 subunit with a variant cytoplasmic domain.

1992 • 120 citations

A human integrin β1 subunit with a unique cytoplasmic domain generated by alternative mRNA processing

1990 • 106 citations

Lack of Platelet Response to Collagen Associated with an Autoantibody against Glycoprotein Ia: A Novel Cause of Acquired Qualitative Platelet Dysfunction

1990 • 106 citations

The Bra/Brb alloantigen system on human platelets

1989 • 96 citations

Na+-independent Cl(-)-HCO-3- exchange in Madin-Darby canine kidney cells. Role in intracellular pH regulation.

1987 • 94 citations

The Arg-Gly-Asp (RGD) recognition site of platelet glycoprotein IIb- IIIa on nonactivated platelets is accessible to high-affinity macromolecules

1992 • 77 citations

Platelet aggregation by basement membrane - associated collagens

1980 • 63 citations

Characterization of the gamma chain platelet binding site on fibrinogen fragment D

1992 • 44 citations

Synthesis of analogs of human platelet membrane glycoprotein IIb-IIIa complex by chicken peripheral blood thrombocytes.

1985 • 37 citations

Effect of a collagen derived octapeptide on different steps of the platelet / collagen interaction

1983 • 28 citations

Human Platelet Glycoprotein Ia

1989 • 24 citations

Deficiency of platelet membrane glycoprotein Ia associated with a decreased platelet adhesion to subendothelium: a defect in platelet spreading

1986 • 14 citations

The Platelet Reactivity of Collagen Type VI

1985 • 11 citations

ROLE OF PLATELET MEMBRANE GLYCOPROTEIN IV IN PLATELET-COLLAGEN INTERACTION: A MICROTITER ASSAY TO STUDY PLATELET ADHERENCE

1987 • 4 citations